Results 81 to 90 of about 652,405 (298)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Current advances in solid-phase microextraction technique as a green analytical sample preparation approach

Green Chemistry Letters and Reviews
Conventional analytical techniques often rely on harmful chemicals, leading to significant environmental pollution, contamination, and waste generation.
Harshika Poojary, Keerthana Selvamuthukumar, Roshna Parveen, Gouri Illanad, Debsmita Mandal, Sophia Koo, Chiranjit Ghosh   +6 more
doaj   +1 more source

Spatial Analyses of Specialized Metabolites: The Key to Studying Function in Hosts

mSystems, 2018
Microbial communities contribute to a wide variety of biological functions in hosts and have the ability to specifically influence the health of those organisms through production of specialized metabolites.
Melissa M. Galey, Laura M. Sanchez
doaj   +1 more source

Food Physical Chemistry and Biophysical Chemistry [PDF]

, 2011
Food Physical Chemistry is considered to be a branch of Food Chemistry^1,2^ concerned with the study of both physical and chemical interactions in foods in terms of physical and chemical principles applied to food systems, as well as the applications of ...
I.C. Baianu
core   +1 more source

Genome-inspired molecular identification in organic matter via Raman spectroscopy

, 2016
Rapid, non-destructive characterization of molecular level chemistry for organic matter (OM) is experimentally challenging. Raman spectroscopy is one of the most widely used techniques for non-destructive chemical characterization, although it currently ...
Bryndzia, L. Taras, Ferralis, Nicola, Grossman, Jeffrey C., Liu, Yun   +3 more
core   +1 more source

Boron isotope ratio (delta B-11) measurements in water framework directive monitoring programs: comparison between double focusing sector field ICP and thermal ionization mass spectrometry [PDF]

, 2010
International audienceThe aim of our research was to compare delta B-11 measurements performed with thermal ionization mass spectrometry (TIMS) and sector field-inductively coupled plasma-mass spectrometry (SF-ICP-MS) and evaluate the feasibility of ...
Aggarwal, Aggarwal, Aggarwal, Agnès Bregnot, Al-Ammar, Allan, Barth, Barth, Bassett, Boulyga, Chetelat, Chetelat, Coetzee, Coplen, David Widory, Demuth, Dongmei Xue, Eisenhut, Eisenhut, Emmanuelle Petelet, Encinar, Gaillardet, Gonfiantini, Gregoire, Gregoire, Gäbler, Heumann, Ishikawa, Jan Bronders, Kasemann, Komor, Kristof Tirez, Lemarchand, Mather, Pascal Boeckx, Spivack, Spivack, Tonarini, Vanhaecke, Vengosh, Weiser, Widory, Widory, Wilfried Brusten, Xue   +44 more
core   +4 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Recent trends in microsampling and reduced-volume sample preparation procedures

Advances in Sample Preparation
The emergence of Green Chemistry (GC), Green Analytical Chemistry (GAC), and Green Sample Preparation (GSP) has significantly influenced the evolution of sample preparation techniques.
Miryam Perrucci, Erika Maria Ricci, Marcello Locatelli, Imran Ali, Fotou R. Mansour, Abuzar Kabir, Halil I. Ulusoy   +6 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source