Results 21 to 30 of about 142,491 (231)

Chemical Methods for Peptide and Protein Production

open access: yesMolecules, 2013
Since the invention of solid phase synthetic methods by Merrifield in 1963, the number of research groups focusing on peptide synthesis has grown exponentially. However, the original step-by-step synthesis had limitations: the purity of the final product
Istvan Toth   +2 more
doaj   +1 more source

Revival of Zeolite‐Templated Nanocarbon Materials: Recent Advances in Energy Storage and Conversion

open access: yesAdvanced Science, 2020
Nanocarbon materials represent one of the hottest topics in physics, chemistry, and materials science. Preparation of nanocarbon materials by zeolite templates has been developing for more than 20 years.
Jun Miao   +7 more
doaj   +1 more source

Chemical insights into the synthetic chemistry of five-membered saturated heterocycles—a transition metal–catalyzed approach

open access: yesFrontiers in Chemistry, 2023
Drug design and delivery is primarily based on the hunt for new potent drug candidates and novel synthetic techniques. Recently, saturated heterocycles have gained enormous attention in medicinal chemistry as evidenced by the medicinal drugs listed in ...
Sunbal   +6 more
doaj   +1 more source

Experimentação em química de compostos organometálicos: preparação do cloreto de dicarbonilciclopentadienilferro(II) Practical in organometallic chemistry: preparation of dicarbonylcyclopentadienyliron(II) chloride

open access: yesQuímica Nova, 2007
In this work, we describe a new method for obtaining [Fe(CO)2[(eta5-C5H5)Cl] employing simple techniques and low-cost reagents. It is worth mentioning that this method is faster than others reported in the literature. It was applied in laboratory classes
Zaine Teixeira   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Covalent Organic Frameworks (COFS): A Review

open access: yesJournal of Applied Sciences and Environmental Management, 2022
The search for supramolecular promising porous crystalline materials with diverse applications such as gas storage, catalysis, chemo-sensing, energy storage, and optoelectronic have led to the design and construction of Covalent Organic Frameworks (COFs)
O.S. Bull   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Recent Advances in Indazole-Derived Heterocycles: Synthetic Strategies, Functionalization, and Therapeutic Potential

open access: yesJournal of Chemistry
Indazole-derived heterocycles have garnered significant attention in recent years due to their versatile chemical structures and wide-ranging biological activities. This review explores the recent progress in the synthesis of indazole-based heterocycles,
Uday V. Bhat   +3 more
doaj   +1 more source

Dendron-Functionalized Surface: Efficient Strategy for Enhancing the Capture of Microvesicles

open access: yesiScience, 2019
Summary: Microvesicles (MVs) are used by various types of cells in the human body for intercellular communication, making them biomarkers of great potential for the early and non-evasive diagnosis of a spectrum of diseases.
Jian-Qiao Jiang   +4 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

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