Chemodynamic Therapy of Glioblastoma Multiforme and Perspectives [PDF]
PharmaceuticsGlioblastoma multiforme (GBM), a potential public health issue, is a huge challenge for the advanced scientific realm to solve. Chemodynamic therapy (CDT) based on the Fenton reaction emerged as a state-of-the-art therapeutic modality to treat GBM ...
Zia Ullah +6 more
doaj +6 more sources
Antibacterial Chemodynamic Therapy: Materials and Strategies [PDF]
BME Frontiers, 2023 The wide and frequent use of antibiotics in the treatment of bacterial infection can cause the occurrence of multidrug-resistant bacteria, which becomes a serious health threat.
Chenyang Jia, Fu-Gen Wu
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When starvation therapy meets chemodynamic therapy
ChemPhysMater, 2022 : In recent years, starvation-primed chemodynamic therapies (ST–CDT) have become a hot topic in the wake of many discoveries related to the aberrant metabolism of cancer cells and their resistance to traditional chemotherapies, as well as altered redox ...
Nicholas Thomas Blum +3 more
doaj +2 more sources
Strategies for enhancing cancer chemodynamic therapy performance [PDF]
Exploration, 2022 Chemodynamic therapy (CDT) has emerged to be a frontrunner amongst reactive oxygen species‐based cancer treatment modalities. CDT utilizes endogenous H2O2 in tumor microenvironment (TME) to produce cytotoxic hydroxyl radicals (•OH) via Fenton or Fenton ...
Deblin Jana, Yanli Zhao
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Cu^{2+}-Chelating Mesoporous Silica Nanoparticles for Synergistic Chemotherapy/Chemodynamic Therapy [PDF]
Pharmaceutics, 2022 In this study, a pH-responsive controlled-release mesoporous silica nanoparticle (MSN) formulation was developed. The MSNs were functionalized with a histidine (His)-tagged targeting peptide (B3int) through an amide bond, and loaded with an anticancer ...
Chen, Wenling +8 more
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Mitochondria-Targeting Chemodynamic Therapy Nanodrugs for Cancer Treatment [PDF]
Frontiers in Pharmacology, 2022 Mitochondria, as one of the most critical subcellular organelles of cancer cells, are very vulnerable and often on the verge of oxidative stress. The classic chemodynamic therapy (CDT) directly employs endogenous chemical energy to trigger reactive ...
Qiaohui Chen +19 more
doaj +3 more sources
Dihydroartemisinin-Loaded Magnetic Nanoparticles for Enhanced Chemodynamic Therapy [PDF]
Frontiers in Pharmacology, 2020 Recently, chemodynamic therapy (CDT) has represented a new approach for cancer treatment with low toxicity and side effects. Nonetheless, it has been a challenge to improve the therapeutic effect through increasing the amount of reactive oxygen species ...
Shengdi Guo +7 more
doaj +4 more sources
Single-atom nanozyme-mediated dihydroartemisinin delivery for self-enhanced chemodynamic therapy and ferroptosis [PDF]
Materials Today BioChemodynamic therapy (CDT), leveraging intracellular iron ions (Fe2+) and hydrogen peroxide (H2O2), is a highly selective therapeutic strategy with significant potential.
Yuanlong Zhang +7 more
doaj +2 more sources
Intelligent gold nanocluster for effective treatment of malignant tumor via tumor-specific photothermal-chemodynamic therapy with AIE guidance. [PDF]
Natl Sci RevPrecise and efficient therapy of malignant tumors is always a challenge. Herein, gold nanoclusters co-modified by aggregation-induced-emission (AIE) molecules, copper ion chelator (acylthiourea) and tumor-targeting agent (folic acid) were fabricated to ...
Chang, Xiaowei +8 more
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Intraparticle Electron Transfer for Long-Lasting Tumor Chemodynamic Therapy. [PDF]
Adv Sci (Weinh)Abstract Chemodynamic therapy (CDT) is a novel tumor treatment method by using hydroxyl radicals ( • OH) to kill cancer cells. However, its therapeutic effects are strictly confined by the short lifespan of • OH and reduced
Yu J +9 more
europepmc +4 more sources