Results 11 to 20 of about 5,044 (221)

When starvation therapy meets chemodynamic therapy

ChemPhysMater, 2022
: In recent years, starvation-primed chemodynamic therapies (ST–CDT) have become a hot topic in the wake of many discoveries related to the aberrant metabolism of cancer cells and their resistance to traditional chemotherapies, as well as altered redox ...
Nicholas Thomas Blum, Lianhua Fu, Jing Lin, Peng Huang   +3 more
doaj   +2 more sources

Strategies for enhancing cancer chemodynamic therapy performance [PDF]

Exploration, 2022
Chemodynamic therapy (CDT) has emerged to be a frontrunner amongst reactive oxygen species‐based cancer treatment modalities. CDT utilizes endogenous H2O2 in tumor microenvironment (TME) to produce cytotoxic hydroxyl radicals (•OH) via Fenton or Fenton ...
Deblin Jana, Yanli Zhao
doaj   +3 more sources

Mitochondria-Targeting Chemodynamic Therapy Nanodrugs for Cancer Treatment [PDF]

Frontiers in Pharmacology, 2022
Mitochondria, as one of the most critical subcellular organelles of cancer cells, are very vulnerable and often on the verge of oxidative stress. The classic chemodynamic therapy (CDT) directly employs endogenous chemical energy to trigger reactive ...
Qiaohui Chen, Qiaohui Chen, Niansheng Li, Niansheng Li, Xiaoyuan Wang, Xiaoyuan Wang, Yuqi Yang, Yuqi Yang, Yuting Xiang, Yuting Xiang, Xingyu Long, Xingyu Long, Jinping Zhang, Jinping Zhang, Jia Huang, Jia Huang, Li Chen, Li Chen, Qiong Huang, Qiong Huang   +19 more
doaj   +3 more sources

Dihydroartemisinin-Loaded Magnetic Nanoparticles for Enhanced Chemodynamic Therapy [PDF]

Frontiers in Pharmacology, 2020
Recently, chemodynamic therapy (CDT) has represented a new approach for cancer treatment with low toxicity and side effects. Nonetheless, it has been a challenge to improve the therapeutic effect through increasing the amount of reactive oxygen species ...
Shengdi Guo, Xianxian Yao, Qin Jiang, Kuang Wang, Yuanying Zhang, Haibao Peng, Jing Tang, Wuli Yang   +7 more
doaj   +4 more sources

DNA nanomachine‐driven chemodynamic therapy against glioblastoma

Aggregate
Chemodynamic therapy (CDT) has shown promising antitumor effects in various malignant tumors. However, its application for glioblastoma (GBM) is significantly hindered by the challenge of delivering CDT agents across the blood‐brain barrier (BBB) and ...
Xiaodie Li, Yufei Lan, Xin Fu, Xin Luo, Jie Chen, Wenxin Zhang, Boming Zuo, Tao Yang, Boyang Liu, Chao Zhang, Hongbo Guo   +10 more
doaj   +2 more sources

Tumor microenvironment-oriented MOFs for chemodynamic therapy

Coordination Chemistry Reviews, 2023
Xiaojiao Di, Zhichao Pei, Yuxin Pei, Tony D. James   +3 more
openaire   +3 more sources

An NIR-II Responsive Nanoplatform for Cancer Photothermal and Oxidative Stress Therapy

Frontiers in Bioengineering and Biotechnology, 2021
Chemodynamic therapy as an emerging therapeutic strategy has been implemented for oncotherapy. However, the reactive oxygen species can be counteracted by the exorbitant glutathione (GSH) produced by the tumor cells before exerting the antitumor effect ...
Bin Huang, Yuanpeng Huang, Han Han, Qiuyue Ge, Dongliang Yang, Yanling Hu, Meng Ding, Yanqing Su, Yanbin He, Yanbin He, Jinjun Shao, Jianfeng Chu, Jianfeng Chu   +12 more
doaj   +1 more source

Tumor microenvironment responsive Mn3O4 nanoplatform for in vivo real-time monitoring of drug resistance and photothermal/chemodynamic synergistic therapy of gastric cancer

Journal of Nanobiotechnology, 2022
Background Postoperative chemotherapy for gastric cancer often causes multidrug resistance (MDR), which has serious consequences for therapeutic effects.
Hanrui Li, Xiaoxia Cai, Tong Yi, Yun Zeng, Jingwen Ma, Lei Li, Liaojun Pang, Na Li, Hao Hu, Yonghua Zhan   +9 more
doaj   +1 more source

Nanosystems for chemodynamic based combination therapy: Strategies and recent advances

Frontiers in Pharmacology, 2022
Chemodynamic therapy (CDT), a newly developed approach for cancer treatment, can convert hydrogen peroxide (H2O2) into toxic hydroxyl radicals (•OH) by using Fenton/Fenton-like reaction to kill tumor cells.
Minghui Li, Wen Zhang, Xiaopeng Xu, Guoying Liu, Mengfei Dong, Kaoxiang Sun, Peng Zhang   +6 more
doaj   +1 more source

A tumor microenvironment-responsive poly(amidoamine) dendrimer nanoplatform for hypoxia-responsive chemo/chemodynamic therapy

Journal of Nanobiotechnology, 2022
Background Chemodynamic therapy is a promising cancer treatment with specific therapeutic effect at tumor sites, as toxic hydroxyl radical (·OH) could only be generated by Fenton or Fenton-like reaction in the tumor microenvironment (TME) with low pH and
Yingchao Hao, Yue Gao, Yu Fan, Changchang Zhang, Mengsi Zhan, Xueyan Cao, Xiangyang Shi, Rui Guo   +7 more
doaj   +1 more source