Results 91 to 100 of about 6,653 (267)

Layered double hydroxides‐based nanozymes for effective biomedical applications: A review and future perspectives

BMEMat, EarlyView.
In this review, we introduced the preparation methods of LDHzymes and discussed their catalytic activity and mechanisms. Subsequently, the applications of LDHzymes in biomedical were discussed. Finally, potential future work on LDHzymes was proposed to better design these new types of nanozymes.
Jiawei Cui, Lu Zhang, Junyi Li, Yue Chen, Sheng Dai, Manfred F. Maitz, Ansha Zhao, Ping Yang   +7 more
wiley   +1 more source

Self-assembled copper-based nanoparticles for enzyme catalysis-enhanced chemodynamic/photodynamic/antiangiogenic tritherapy against hepatocellular carcinoma

Journal of Nanobiotechnology
As an emerging cancer treatment strategy, reactive oxygen species-based tumor catalytic therapies face enormous challenges due to hypoxia and the overexpression of glutathione (GSH) in the tumor microenvironment.
Yaping Wang, Xun Zhang, Yunfeng Ma, Xiaobo Zhou, Weijun Xu, Sida Qin, Chengcheng Yang   +6 more
doaj   +1 more source

Recyclable Endogenous H2S Activation of Self‐Assembled Nanoprobe with Controllable Biodegradation for Synergistically Enhanced Colon Cancer‐Specific Therapy

Advanced Science, 2022
Excessive production of hydrogen sulfide (H2S) plays a crucial role in the progress of colon cancer. Construction of tumor‐specific H2S‐activated smart nanoplatform with controllable biodegradation is of great significance for precise and sustainable ...
Junqing Huang, Zhiming Deng, Shenghui Bi, Xingwang Wen, Songjun Zeng   +4 more
doaj   +1 more source

Tumor-Targeted Conjugated Polymer Nanoparticles with Encapsulated Iron and Its Biomedical Application for In Vitro Killing of Melanoma Cell Lines Through Ferroptosis Assisted Chemodynamic Therapy (CDT) [PDF]

, 2019
Melanoma represents one of the most aggressive and lethal forms of skin cancer, with annually rising incidences throughout the world. Although chemotherapy modalities remain the mainstay of treatment, the therapeutic potential of chemotherapy typically ...
Jasim, Khalaf
core   +1 more source

Multifunctional nano-bomb based on Fe-COF for targeted tumor dual chemodynamic therapy and bioimaging with enhanced ferroptosis and H2O2 self-supply [PDF]

, 2023
Pan Zhao, Liyang Gong, Le Chang, Meijuan Geng, Huiping Du, Siyu Meng, Liangliang Dai   +6 more
openalex   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

PDGFB targeting biodegradable FePt alloy assembly for MRI guided starvation-enhancing chemodynamic therapy of cancer

Journal of Nanobiotechnology, 2022
The application of chemodynamic therapy (CDT) for cancer is a serious challenge owing to the low efficiency of the Fenton catalyst and insufficient H2O2 expression in cells.
Caiyun Zhang, Zhiguo Leng, Yinfeng Wang, Lang Ran, Xia Qin, Huan Xin, Xiaotong Xu, Guilong Zhang, Zhaowei Xu   +8 more
doaj   +1 more source

Multivariate Metal-Organic Frameworks based pH-responsive dual-drug delivery system for chemotherapy and chemodynamic therapy [PDF]

, 2023
Muhammad Usman Akbar, Arslan Akbar, Umair Ali Khan Saddozai, Malik Ihsan Ullah Khan, Muhammad Zaheer, Muhammad Badar   +5 more
openalex   +1 more source

Theranostic nanoplatform for high‐performance dual‐modal magnetic resonance imaging‐guided therapy of orthotopic hepatocellular carcinoma

BMEMat, EarlyView.
This article introduces a biomimetic Mn‐doped polydopamine nanoplatform (HAMM NPs) coated with cancer cell membranes. It enables targeted hepatocellular carcinoma theranostics via T1/T2 dual‐mode magnetic resonance imaging and tumor microenvironment‐triggered sonodynamic therapy/chemodynamic therapy, achieving potent antitumor efficacy in subcutaneous ...
Jiayin Lin, Wenbo Chen, Xiuqi Hou, Kai Wang, Fan Liu, Ruling Zhang, Zhong Cao, Jian Zheng   +7 more
wiley   +1 more source

Ternary NiCoTi-layered double hydroxide nanosheets as a pH-responsive nanoagent for photodynamic/chemodynamic synergistic therapy

Fundamental Research
Combining photodynamic therapy (PDT) with chemodynamic therapy (CDT) has been proven to be a promising strategy to improve the treatment efficiency of cancer, because of the synergistic therapeutic effect arising between the two modalities.
Tingting Hu, Zhan Zhou, Jiajia Zha, Gareth R. Williams, Zhikang Wu, Wei Zhao, Weicheng Shen, Hai Li, Xisheng Weng, Ruizheng Liang, Chaoliang Tan   +10 more
doaj   +1 more source