Results 21 to 30 of about 6,653 (267)

Hollow Mesoporous CeO₂-Based Nanoenzymes Fabrication for Effective Synergistic Eradication of Malignant Breast Cancer via Photothermal–Chemodynamic Therapy

Pharmaceutics, 2022
CeO2-based nanoenzymes present a very promising paradigm in cancerous therapy, as H2O2 can be effectively decomposed under the electron transmit between Ce3+ and Ce4+. However, the limitations of endogenous H2O2 and intracellular low Fenton-like reaction
Huaxin Tan, Yongzhen Li, Jiaying Ma, Peiyuan Wang, Qiaoling Chen, Lidan Hu   +5 more
doaj   +1 more source

Recent advances in Fenton and Fenton-like reaction mediated nanoparticle in cancer therapy [PDF]

, 2023
Fenton and Fenton like reaction have been well clarified as efficient reactive oxygen species (ROS) sources in tumor, and have been widely developed into a cancer treatment method.
Han, Huijie, Li, Jiachen, Santos, Hélder A.   +2 more
core   +1 more source

Co-Loading of Inorganic Nanoparticles and Natural Oil in the Electrospun Janus Nanofibers for a Synergetic Antibacterial Effect [PDF]

, 2022
Side-by-side electrospinning is a powerful but challenging technology that can be used to prepare Janus nanofibers for various applications. In this work, cellulose acetate (CA) and polycaprolactone (PCL) were used as polymer carriers for silver ...
Bligh, Sim Wan Annie, Wang, Menglong, Williams, Gareth R, Yu, Deng-Guang   +3 more
core   +1 more source

An NIR-II Responsive Nanoplatform for Cancer Photothermal and Oxidative Stress Therapy

Frontiers in Bioengineering and Biotechnology, 2021
Chemodynamic therapy as an emerging therapeutic strategy has been implemented for oncotherapy. However, the reactive oxygen species can be counteracted by the exorbitant glutathione (GSH) produced by the tumor cells before exerting the antitumor effect ...
Bin Huang, Yuanpeng Huang, Han Han, Qiuyue Ge, Dongliang Yang, Yanling Hu, Meng Ding, Yanqing Su, Yanbin He, Yanbin He, Jinjun Shao, Jianfeng Chu, Jianfeng Chu   +12 more
doaj   +1 more source

Nanosystems for chemodynamic based combination therapy: Strategies and recent advances

Frontiers in Pharmacology, 2022
Chemodynamic therapy (CDT), a newly developed approach for cancer treatment, can convert hydrogen peroxide (H2O2) into toxic hydroxyl radicals (•OH) by using Fenton/Fenton-like reaction to kill tumor cells.
Minghui Li, Wen Zhang, Xiaopeng Xu, Guoying Liu, Mengfei Dong, Kaoxiang Sun, Peng Zhang   +6 more
doaj   +1 more source

A tumor microenvironment-responsive poly(amidoamine) dendrimer nanoplatform for hypoxia-responsive chemo/chemodynamic therapy

Journal of Nanobiotechnology, 2022
Background Chemodynamic therapy is a promising cancer treatment with specific therapeutic effect at tumor sites, as toxic hydroxyl radical (·OH) could only be generated by Fenton or Fenton-like reaction in the tumor microenvironment (TME) with low pH and
Yingchao Hao, Yue Gao, Yu Fan, Changchang Zhang, Mengsi Zhan, Xueyan Cao, Xiangyang Shi, Rui Guo   +7 more
doaj   +1 more source

Synergistic Radiosensitization Mediated by Chemodynamic Therapy via a Novel Biodegradable Peroxidases Mimicking Nanohybrid

Frontiers in Oncology, 2022
PurposeReactive oxygen species (ROS) are practically essential in radiotherapy to damage cancer cells; however, they are always inadequate for some malignant entities.
Jun Zhang, Dazhen Jiang, Meng Lyu, Shiqi Ren, Yunfeng Zhou, Zhen Cao   +5 more
doaj   +1 more source

Manganese Sulfate Nanocomposites Fabricated by Hot-Melt Extrusion for Chemodynamic Therapy of Colorectal Cancer

Pharmaceutics, 2023
The development of metal salts-based nanocomposites is highly desired for the Fenton or Fenton-like reaction-based chemodynamic therapy of cancer. Manganese sulfate (MnSO4)-dispersed nanoparticles (NPs) were fabricated with a hot-melt extrusion (HME ...
Da In Jeong, Sungyun Kim, Ja Seong Koo, Song Yi Lee, Minju Kim, Kwang Yeol Kim, Md Obyedul Kalam Azad, Mrinmoy Karmakar, Seongnam Chu, Byung-Jo Chae, Wie-Soo Kang, Hyun-Jong Cho   +11 more
doaj   +1 more source

Utilizing Iron for Targeted Lipid Peroxidation as Anticancer Option of Integrative Biomedicine: A Short Review of Nanosystems Containing Iron [PDF]

, 2020
Traditional concepts of life sciences consider oxidative stress as a fundamental process of aging and various diseases including cancer, whereas traditional medicine recommends dietary intake of iron to support physiological functions of the organism ...
Borović Šunjić, Suzana, Jaganjac, Morana, Žarković, Neven   +2 more
core   +1 more source

GSH/ROS Dual-Responsive Supramolecular Nanoparticles Based on Pillar[6]arene and Betulinic Acid Prodrug for Chemo–Chemodynamic Combination Therapy

Molecules, 2021
Chemodynamic therapy (CDT) based on intracellular Fenton reactions is attracting increasing interest in cancer treatment. A simple and novel method to regulate the tumor microenvironment for improved CDT with satisfactory effectiveness is urgently needed.
Peng Zhu, Weidan Luo, Jianqiang Qian, Chi Meng, Wenpei Shan, Zhongyuan Xu, Wei Zhang, Xin Liu, Yong Ling   +8 more
doaj   +1 more source