Results 61 to 70 of about 6,653 (267)
Implantable composite fibres with Self-supplied H2O2 for localized chemodynamic therapy [PDF]
, 2020 The anticancer efficacy of chemodynamic therapy (CDT) is considerably restrained by the inadequate content of H2O2 within tumor microenvironment (TME), unexpected oxidation of Fenton agents and low targeting efficiency of particulate therapeutic ...
Fu, Y +6 more
core
Trace minerals in human health: iron, zinc, copper, manganese and fluorine [PDF]
, 2019 Trace elements exist in the environment in small amounts but play an essential part in sustaining various physiological and metabolic processes occurring within living tissues, as enzymes structure and function, bone and blood maintenance, immune ...
Ferreira da Vinha, Ana +3 more
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Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects
Advanced Healthcare Materials, EarlyView.Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt +7 more
wiley +1 more source
Results in ChemistryTumor microenvironment (TME) is characterized by low pH, high hydrogen peroxide (H2O2) concentration and severe hypoxia, which lead to tumor progression, metastasis and drug resistance.
Yunji Sun +6 more
doaj +1 more source
Recent advances in nanomaterial-based drug delivery systems for melanoma therapy [PDF]
, 2023 Background and Purpose Safe and effective drug delivery is crucial for the treatment of cancer, which is quite impossible to achieve through traditional methods.
Jena, Goutam Kumar +2 more
core +2 more sources
Precise Chemodynamic Therapy of Cancer by Trifunctional Bacterium-Based Nanozymes
ACS Nano, 2021 Chemodynamic therapy (CDT) destroys cancer cells by converting H2O2 or O2 into reactive oxygen species (ROS), but its therapeutic efficacy is restricted by the antioxidant capacity of tumor. Previous solutions focused on strengthening the nanodrugs with the ability to increase ROS production or weaken the antioxidant capacity of cancer cells ...
Weiyun Zhang +9 more
openaire +4 more sources
Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Nature Communications, 2020 The supply of oxygen species for dynamic therapy is a major limitation. Here, the authors report on a complex of calcium peroxide with photo/chemo dynamic agents, where NIR heating causes the release of calcium peroxide to generate oxygen and hydrogen ...
Conghui Liu +7 more
doaj +1 more source
Design of a two-dimensional interplanar heterojunction for catalytic cancer therapy
Nature Communications, 2022 Chemodynamic therapy relies on Fenton or Fenton-like reactions to produce hydroxyl radical in the tumor region. Here the authors design a two-dimensional interplanar heterojunction with in situ hydroxyl radical generation under ultrasound irradiation ...
Yong Kang +7 more
doaj +1 more source
Acta Pharmaceutica Sinica B, 2022 Carrier-free multi-component self-assembled nano-systems have attracted widespread attention owing to their easy preparation, high drug-loading efficiency, and excellent therapeutic efficacy.
Xiaojie Chen +9 more
doaj +1 more source