Nanoparticle-driven Novel Cancer Therapeutics: Catalysis for Homeostasis Disruption [PDF]
, 2023 La terapia catalítica contra el cáncer tiene como objetivo inducir la muerte de las células tumorales mediante el uso de reacciones químicas perjudiciales, aprovechando las diferencias químicas existentes entre las células cancerosas y las células sanas.
Bonet Aletá, Javier +2 more
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Tumor microenvironment responsive metal nanoparticles in cancer immunotherapy [PDF]
, 2023 Malignant tumors have a unique tumor microenvironment (TME), which includes mild acidity, hypoxia, overexpressed reactive oxygen species (ROS), and high glutathione (GSH) levels, among others. Recently, TME regulation approaches have attracted widespread
Lijuan Zhang +6 more
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Journal of Nanobiotechnology, 2021 Lactate plays a critical role in tumorigenesis, invasion and metastasis. Exhausting lactate in tumors holds great promise for the reversal of the immunosuppressive tumor microenvironment (TME).
Ruiqing He +13 more
doaj +1 more source
Drug-loaded hybrid hydrogels for sonodynamic-chemodyanmic therapy and tumor metastasis suppression [PDF]
, 2023 Introduction: Although various therapies have been adopted to treat cancer, metastasis of tumor cells still is a big challenge that compromises therapeutic benefits.Methods: We herein report an injectable drug-loaded hybrid hydrogel that can achieve ...
Changcun Liu +5 more
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Intelligent gold nanocluster for effective treatment of malignant tumor via tumor-specific photothermal-chemodynamic therapy with AIE guidance. [PDF]
Precise and efficient therapy of malignant tumors is always a challenge. Herein, gold nanoclusters co-modified by aggregation-induced-emission (AIE) molecules, copper ion chelator (acylthiourea) and tumor-targeting agent (folic acid) were fabricated to ...
Chang, Xiaowei +8 more
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Implantable composite fibres with Self-supplied H2O2 for localized chemodynamic therapy [PDF]
, 2020 The anticancer efficacy of chemodynamic therapy (CDT) is considerably restrained by the inadequate content of H2O2 within tumor microenvironment (TME), unexpected oxidation of Fenton agents and low targeting efficiency of particulate therapeutic ...
Fu, Y +6 more
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Tumor Microenvironment-Adaptive Nanoplatform Synergistically Enhances Cascaded Chemodynamic Therapy
Bioactive Materials, 2023 Chemodynamic therapy (CDT), a noninvasive strategy, has emerged as a promising alternative to conventional chemotherapy for treating tumors. However, its therapeutic effect is limited by the amount of H2O2, pH value, the hypoxic environment of tumors, and it has suboptimal tumor-targeting ability.
Yuemin Wang +9 more
openaire +3 more sources
Construction of Novel Nanocomposites (Cu-MOF/GOD@HA) for Chemodynamic Therapy [PDF]
, 2021 The emerging chemodynamic therapy (CDT) has received an extensive attention in recent years. However, the efficiency of CDT is influenced due to the limitation of H2O2 in tumor. In this study, we designed and synthesized a novel core-shell nanostructure,
Chen, Wei +4 more
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Trace minerals in human health: iron, zinc, copper, manganese and fluorine [PDF]
, 2019 Trace elements exist in the environment in small amounts but play an essential part in sustaining various physiological and metabolic processes occurring within living tissues, as enzymes structure and function, bone and blood maintenance, immune ...
Ferreira da Vinha, Ana +3 more
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Biomimetic Copper-Doped Polypyrrole Nanoparticles For Enhanced Cancer Low-Temperature Photothermal therapy [PDF]
, 2023 INTRODUCTION: Photothermal therapy (PTT) has a significant potential for its application in precision tumour therapy. However, PTT-induced hyperthermia may damage healthy tissues and trigger the expression of heat shock proteins (HSPs), thereby ...
Cai, Wei +6 more
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