Results 11 to 20 of about 41,400 (225)

Radiological Loco-Regional Treatments for Cholangiocarcinoma: A Systematic Review of the Literature. [PDF]

Liver Int
ABSTRACT Cholangiocarcinoma (CCA) is the second most common primary liver cancer and is being diagnosed with increasing frequency worldwide. We performed a systematic review on radiofrequency (RFA), microwave (MWA), irreversible electroporation (IRE), trans‐arterial chemoembolization (TACE) and selective internal radiation therapy (SIRT) in CCA. Thirty‐
Pallas D, Campani C, Sutter O, Nahon P, Ganne-Carrié N, Seror O, Nault JC.   +6 more
europepmc   +2 more sources

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Liver resection or combined chemoembolization and radiofrequency ablation improve survival in patients with hepatocellular carcinoma [PDF]

, 2007
Background/ Aims: To evaluate the long-term outcome of surgical and non-surgical local treatments of patients with hepatocellular carcinoma (HCC). Methods: We stratified a cohort of 278 HCC patients using six independent predictors of survival according ...
Angelika Schrader, Bloomston M, Bosch FX, Burkhard Göke, Castells A, Christian Graeb, Christoph Jüngst, Curley SA, Dieter Jüngst, Florian Löhe, Franco D, Goldberg SN, Gundula Straub, Horst-Günter Rau, Karl-Walter Jauch, Kotoh K, Livraghi T, Livraghi T, Livraghi T, Maximilian Reiser, Qian J, Ralf-Thorsten Hoffmann, Rolf Schauer, Rossi S, Rossi S, Ryder SD, Sasaki Y, Selin Dogan, Takenaka K, Thomas Helmberger, Tobias Jakobs, Tobias Waggershauser, Wolfgang H. Caselmann   +32 more
core   +1 more source

Polyethylene Glycol Epirubicin-Loaded Transcatheter Arterial Chemoembolization Procedures Utilizing a Combined Approach with 100 and 200 μm Microspheres: A Promising Alternative to Current Standards [PDF]

, 2019
PURPOSE:To report clinical effectiveness, toxicity profile, and prognostic factors of combined 100 μm ± 25 and 200 μm ± 50 epirubicin-loaded polyethylene glycol (PEG) microsphere drug-eluting embolic transcatheter arterial chemoembolization protocol in ...
Argirò, Renato, Bezzi, M., Catalano, C, Corona, M, Corradini, Sg, Corsi, A, De Rubeis, G, Fiorentino, F, Lucatelli, Pierleone, Mennini, G, Nardis, Pg, Rocco, Bianca, Saba, Luca   +12 more
core   +1 more source

TREATMENT OUTCOMES OF COLORECTAL CANCER WITH BILATERAL LIVER METASTASES

Сибирский онкологический журнал, 2017
The purpose of the research: to develop an effective treatment regimen for patients with synchronous liver metastases from colorectal cancer. Material and methods. The study included 126 patients with colon cancer and synchronous liver metastases.
A. S. Zagainov, A. V. Shelekhov, V. V. Dvornichenko, R. I. Rasulov, R. A. Zubkov   +4 more
doaj   +1 more source

Transarterial RAdioembolization versus ChemoEmbolization for the treatment of hepatocellular carcinoma (TRACE) : study protocol for a randomized controlled trial [PDF]

, 2012
Background: Hepatocellular carcinoma is a primary malignant tumor of the liver that accounts for an important health problem worldwide. Only 10 to 15% of hepatocellular carcinoma patients are suitable candidates for treatment with curative intent, such ...
Al Younis, Imad, Coenraad, Minneke J, Defreyne, Luc, Lam, Marnix GEH, Lambert, Bieke, Seinstra, Beatrijs A, van den Bosch, Maurice AAJ, van Erkel, Arian R, van Erpecum, Karel J, van Hoek, Bart, Van Vlierberghe, Hans, Verkooijen, Helena M   +11 more
core   +1 more source

A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma. [PDF]

, 2015
Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver ...
Busuttil, Ronald W, Faltermeier, Claire, Zarrinpar, Ali   +2 more
core   +2 more sources

Chemoembolizing hepatocellular carcinoma with microsphere cored with arsenic trioxide microcrystal

Drug Delivery, 2020
Chemoembolization for hepatocellular carcinoma (HCC) is often suboptimal due to multiple involved signaling and lack of effective drugs. Arsenic trioxide (ATO) is a potent chemotherapeutic agent, which can target multiple signaling and have substantial ...
Degang Kong, Tao Jiang, Jian Liu, Xinyi Jiang, Bei Liu, Cheng Lou, Baobing Zhao, Steven L. Carroll, Gong Feng   +8 more
doaj   +1 more source

Low Psoas-Muscle index is associated with decreased survival in hepatocellular carcinoma treated with transarterial chemoembolization

Annals of Medicine, 2022
Purpose Skeletal muscle index (SMI) is a promising predictor of clinical outcomes in patients with malignant diseases. As a simpler surrogate of sarcopenia-psoas muscle index (PMI), its predict value for overall survival (OS) after transarterial ...
Jin-Xing Zhang, Hai-Tao Yan, Ye Ding, Jin Liu, Sheng Liu, Qing-Quan Zu, Hai-Bin Shi   +6 more
doaj   +1 more source

Yttrium-90 Selective Internal Radiation Therapy with Glass Microspheres for Hepatocellular Carcinoma: Current and Updated Literature Review. [PDF]

, 2016
Hepatocellular carcinoma is the most common primary liver cancer and it represents the majority of cancer-related deaths in the world. More than 70% of patients present at an advanced stage, beyond potentially curative options.
Alanis, Lourdes, Cho, Sung-Ki, Lee, Edward Wolfgang, Saab, Sammy   +3 more
core   +1 more source