Results 11 to 20 of about 26,247 (187)

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Comparative Analysis of Image Quality and Adverse Events between Iopamidol 250 and Ioversol 320 in Hepatic Angiography for Transcatheter Arterial Chemoembolization

대한영상의학회지, 2020
Purpose This study aimed to compare the image quality and adverse events between Iopamidol 250 and Ioversol 320 usage during transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC).
Min Jae Gu, Jae Hyuck Yi, Young Hwan Kim, Hee Jung Lee, Ung Rae Kang, Seung Woo Ji   +5 more
doaj   +1 more source

TREATMENT OUTCOMES OF COLORECTAL CANCER WITH BILATERAL LIVER METASTASES

Сибирский онкологический журнал, 2017
The purpose of the research: to develop an effective treatment regimen for patients with synchronous liver metastases from colorectal cancer. Material and methods. The study included 126 patients with colon cancer and synchronous liver metastases.
A. S. Zagainov, A. V. Shelekhov, V. V. Dvornichenko, R. I. Rasulov, R. A. Zubkov   +4 more
doaj   +1 more source

Low Psoas-Muscle index is associated with decreased survival in hepatocellular carcinoma treated with transarterial chemoembolization

Annals of Medicine, 2022
Purpose Skeletal muscle index (SMI) is a promising predictor of clinical outcomes in patients with malignant diseases. As a simpler surrogate of sarcopenia-psoas muscle index (PMI), its predict value for overall survival (OS) after transarterial ...
Jin-Xing Zhang, Hai-Tao Yan, Ye Ding, Jin Liu, Sheng Liu, Qing-Quan Zu, Hai-Bin Shi   +6 more
doaj   +1 more source

Chemoembolizing hepatocellular carcinoma with microsphere cored with arsenic trioxide microcrystal

Drug Delivery, 2020
Chemoembolization for hepatocellular carcinoma (HCC) is often suboptimal due to multiple involved signaling and lack of effective drugs. Arsenic trioxide (ATO) is a potent chemotherapeutic agent, which can target multiple signaling and have substantial ...
Degang Kong, Tao Jiang, Jian Liu, Xinyi Jiang, Bei Liu, Cheng Lou, Baobing Zhao, Steven L. Carroll, Gong Feng   +8 more
doaj   +1 more source

Balloon-occluded transarterial chemoembolization for hepatocellular carcinoma: History, background, and the roles

International Journal of Gastrointestinal Intervention, 2020
Super-selective lipiodol balloon-occluded transarterial chemoembolization (SSLB-TACE) increases lipiodol accumulation in the targeted nodule. To understand the mechanism of increased accumulation, it is necessary to understand intra-hepatic collateral ...
Toshiyuki Irie, Nobuyuki Takahashi, Sodai Hoshiai   +2 more
doaj   +1 more source

Development of cisplatin-loaded hydrogels for trans-portal vein chemoembolization in an orthotopic liver cancer mouse model

Drug Delivery, 2021
Transarterial chemoembolization is a standard treatment for intermediate-stage hepatocellular carcinoma (HCC). This study evaluated the anti-tumor effect of the semi-interpenetrating network (IPN) hydrogel as a novel embolic material for trans-portal ...
Xinxiang Yang, Wai-Ho Oscar Yeung, Kel Vin Tan, Tak-Pan Kevin Ng, Li Pang, Jie Zhou, Jinyang Li, Changxian Li, Xiangcheng Li, Chung Mau Lo, Weiyuan John Kao, Kwan Man   +11 more
doaj   +1 more source

Survival of patients with intermediate stage hepatocellular carcinoma treated with superselective transarterial chemoembolization using doxorubicin-loaded DC Bead under cone-beam computed tomography control

Radiology and Oncology, 2016
The purpose of this retrospective study was to evaluate treatment response, adverse events and survival rates of patients with intermediate stage HCC treated with superselective doxorubicin-loaded DC Bead transarterial chemoembolization (DEBDOX) under ...
Popovic Peter, Stabuc Borut, Jansa Rado, Garbajs Manca   +3 more
doaj   +1 more source

Variations in the Origins of Inferior Phrenic Arteries—An Evaluation with 256 Slice Multidetector Computed Tomography

Journal of Clinical Interventional Radiology ISVIR, 2020
Aim To evaluate the frequency and pattern of variations in the origins of right inferior phrenic artery (RIPA) and left inferior phrenic artery (LIPA) on 256 slice multidetector computed tomography (MDCT).
Chinmay Bhimaji Kulkarni, Sreekumar Karumathil Pullara, Nirmal Kumar Prabhu, Minnie Pillay, Srikanth Moorthy   +4 more
doaj   +1 more source

Evaluation of the effectiveness of transarterial chemoembolization irinotecan-loaded with drug-saturable microspheres for the treatment of patients with neuroendocrine tumors with liver metastases [PDF]

Клиническая практика, 2023
Background: Since 2021, transarterial chemoembolization of the hepatic arteries (TACE) has been included in the recommendations of professional communities for the treatment of metastases of neuroendocrine liver tumors (NEO).
Elena A. Zvezdkina, Anna G. Kedrova, Dmitry P. Lebedev, Sergey E. Krasilnicov, Oleg V. Krestyaninov, Tatevic A. Greyan, Dmitry N. Panchenkov, Yulia A. Stepanova   +7 more
doaj   +1 more source