Results 11 to 20 of about 62,056 (139)

Effect of storage time on the chemokine storage and chemokine scavenging function of erythrocyte atypical chemokine receptor 1

Zhongguo shuxue zazhi, 2022
Objective To determine the effect of storage time on the chemokine storage and chemokine scavenging function of erythrocyte atypical chemokine receptor 1(ACKR1). Methods Samples from six bags of red blood cells product, split into two gruoups(10 mL each),
Shihang ZHOU, Ni WANG, Ming LIU, Xiaohua LIANG   +3 more
doaj   +2 more sources

Expression of Ccl11 associates with immune response modulation and protection against neuroinflammation in rats. [PDF]

PLoS ONE, 2012
Multiple sclerosis (MS) is a polygenic disease characterized by inflammation and demyelination in the central nervous system (CNS), which can be modeled in experimental autoimmune encephalomyelitis (EAE).
Milena Z Adzemovic, Johan Öckinger, Manuel Zeitelhofer, Sonja Hochmeister, Amennai Daniel Beyeen, Atul Paulson, Alan Gillett, Melanie Thessen Hedreul, Ruxandra Covacu, Hans Lassmann, Tomas Olsson, Maja Jagodic   +11 more
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CCL11, a novel mediator of inflammatory bone resorption

Scientific Reports, 2017
Normal bone homeostasis, which is regulated by bone-resorbing osteoclasts and bone-forming osteoblasts is perturbed by inflammation. In chronic inflammatory disease with disturbed bone remodelling, e.g. rheumatoid arthritis, patients show increased serum
Elin Kindstedt, Cecilia Koskinen Holm, Rima Sulniute, Irene Martinez-Carrasco, Richard Lundmark, Pernilla Lundberg   +5 more
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SNPs in inflammatory genes CCL11, CCL4 and MEFV in a fibromyalgia family study.

PLoS ONE, 2018
BackgroundFibromyalgia (FM) is a chronic pain syndrome with a high incidence in females that may involve activation of the immune system. We performed exome sequencing on chemokine genes in a region of chromosome 17 identified in a genome-wide family ...
Zhifang Zhang, Jinong Feng, Allen Mao, Keith Le, Deirdre La Placa, Xiwei Wu, Jeffrey Longmate, Claudia Marek, R Paul St Amand, Susan L Neuhausen, John E Shively   +10 more
doaj   +2 more sources

Eotaxin-1/CCL11 promotes cellular senescence in human-derived fibroblasts through pro-oxidant and pro-inflammatory pathways [PDF]

Frontiers in Immunology, 2023
IntroductionEotaxin-1/CCL11 is a pivotal chemokine crucial for eosinophil homing to the lungs of asthmatic patients. Recent studies also suggest that CCL11 is involved in the aging process, as it is upregulated in elderly, and correlated with shorter ...
Patrícia Lavandoski, Vinícius Pierdoná, Rafael Moura Maurmann, Lucas Kich Grun, Fatima T. C. R. Guma, Florencia María Barbé-Tuana, Florencia María Barbé-Tuana   +6 more
doaj   +3 more sources

IL-4 Modulates CCL11 and CCL20 Productions from IL-1β-Stimulated Human Periodontal Ligament Cells [PDF]

Cellular Physiology and Biochemistry, 2016
Background/Aims: IL-4 is a multifunctional cytokine that is related with the pathological conditions of periodontal disease. However, it is uncertain whether IL-4 could control T cells migration in periodontal lesions.
Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki, Takashi Matsuo   +4 more
doaj   +4 more sources

Revisiting the Role of Eotaxin-1/CCL11 in Psychiatric Disorders [PDF]

Frontiers in Psychiatry, 2018
Eotaxin-1/CCL11 is a chemokine originally implicated in the selective recruitment of eosinophils into inflammatory sites during allergic reactions, being thoroughly investigated in asthma, allergic rhinitis, and other eosinophil-related conditions ...
Antonio L. Teixeira, Antonio L. Teixeira, Clarissa S. Gama, Natalia P. Rocha, Natalia P. Rocha, Mauro M. Teixeira   +5 more
doaj   +4 more sources

Suppressor of cytokine signalling (SOCS) 1 and 3 enhance cell adhesion and inhibit migration towards the chemokine eotaxin/CCL11 [PDF]

FEBS Letters, 2010
Suppressors of cytokine signalling (SOCS) proteins regulate signal transduction, but their role in responses to chemokines remains poorly understood. We report that cells expressing SOCS1 and 3 exhibit enhanced adhesion and reduced migration towards the chemokine CCL11.
Stevenson, N, McFarlane, C, Ong, S, Nahlik, K, Kelvin, A, Addley, MR, Long, A, Greaves, D, O'Farrelly, C, Johnston, J   +9 more
openaire   +6 more sources

Prognostic significance of chemokines CCL11 and CCL5 modulated by low-density lipoprotein cholesterol in colon cancer patients with normal body mass index [PDF]

Annals of Translational Medicine, 2021
Many studies have shown an elevated level of cholesterol in colon tumors as compared to normal tissue. Obesity and high low-density lipoprotein cholesterol (LDL-C) are known risk factors for colon cancer. However, the role of LDL-C in colon cancer patients with normal body mass index (BMI) remains elusive.Levels of serum cholesterol and oxysterols were
Wang, Caihua, Zou, Yi, Pan, Chi, Shao, Liming, Ding, Zonghui, Zhang, Yunzhu, Ye, Jun, Li, Peiwei, Ren, Yuezhong, Zhu, Chunpeng   +9 more
openaire   +2 more sources

Involvement of Eotaxins (CCL11, CCL24, CCL26) in Pathogenesis of Osteopenia and Osteoporosis

Iranian Journal of Public Health, 2020
Background: The purpose of this study was to investigate the role of eotaxin family members including C-C motif chemokine 11 (CCL11), C-C motif chemokine 24 (CCL24), and C-C motif chemokine 26 (CCL26) as the subgroups of CC-chemokine in patients affected
Hadis AHMADI, Hossein KHORRAMDELAZAD, Gholamhossein HASSANSHAHI, Mitra ABBASI FARD, Zahra AHMADI, Mojgan NOROOZI KARIMABAD, Majid MOLLAHOSSEINI   +6 more
doaj   +1 more source