Results 31 to 40 of about 62,056 (139)

Chemokine receptor CCR1: A new target for progressive kidney disease [PDF]

, 2005
Infiltrating leukocytes are thought to contribute to the progression of kidney disease. Locally produced chemokines guide circulating leukocytes into the kidney, which renders therapeutic blockade of respective chemokine receptors on the leukocyte ...
Hans-Joachim Anders, Ninichuk, Volha, Anders, Hans-Joachim, Volha Ninichuk   +3 more
core   +1 more source

Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5)

Frontiers in Pharmacology, 2023
Atypical chemokine receptors (ACKRs) play pivotal roles in immune regulation by binding chemokines and regulating their spatial distribution without inducing G-protein activation.
Remy Bonnavion, Remy Bonnavion, Shangmin Liu, Haruya Kawase, Kenneth Anthony Roquid, Stefan Offermanns, Stefan Offermanns, Stefan Offermanns, Stefan Offermanns   +8 more
doaj   +1 more source

Cancer-Associated Fibroblasts Promote Tumor Aggressiveness in Head and Neck Cancer through Chemokine Ligand 11 and C-C Motif Chemokine Receptor 3 Signaling Circuit

, 2022
SIMPLE SUMMARY: Certain tumor aggressiveness-associated mediators from cancer-associated fibroblasts (CAFs) in tumor microenvironment have been reported.
Wen-Yen Huang, Yi-Ming Chang, Tsai-Yu Lee, Lin, Yu-Chun, Yaoh-Shiang Lin, Lee, Tsai-Yu, Su-Feng Chen, Chen, Su-Feng, Chang, Yi-Ming, Shin Nieh, Yang, Kuender D., Huang, Wen-Yen, Yu-Chun Lin, Kuender D. Yang, Lin, Yaoh-Shiang, Nieh, Shin   +15 more
core   +1 more source

Distinct CCL2, CCL5, CCL11, CCL27, IL-17, IL-6, BDNF serum profiles correlate to different job-stress outcomes

Neurobiology of Stress, 2018
Chronic psychosocial stress at workplace is an important factor in the development of physical and mental illness. Objective biological measures of chronic stress are still lacking, but inflammatory response and growth factors are increasingly considered
Alessio Polacchini, Damiano Girardi, Alessandra Falco, Nunzia Zanotta, Manola Comar, Nicola Alberto De Carlo, Enrico Tongiorgi   +6 more
doaj   +1 more source

Chemokine profile in women with moderate to severe anxiety and depression during pregnancy

BMC Pregnancy and Childbirth, 2021
Background Cytokine levels have been extensively described in pregnant subjects under normal and pathological conditions, including mood-related disorders. Concerning chemokines, very few studies have reported their association with psychiatric disorders
Ignacio Camacho-Arroyo, Mónica Flores-Ramos, Ismael Mancilla-Herrera, Fausto Moisés Coronel Cruz, Joselin Hernández-Ruiz, Gabriela Pellón Diaz, Blanca Farfán Labonne, María del Pilar Meza-Rodríguez, Philippe Leff Gelman   +8 more
doaj   +1 more source

Cholesterol Is a Dose-Dependent Positive Allosteric Modulator of CCR3 Ligand Affinity and G Protein Coupling

Frontiers in Molecular Biosciences, 2021
Cholesterol as an allosteric modulator of G protein-coupled receptor (GPCR) function is well documented. This quintessential mammalian lipid facilitates receptor–ligand interactions and multimerization states.
Evan van Aalst, Benjamin J. Wylie
doaj   +1 more source

Genetic ancestry and population differences in levels of inflammatory cytokines in women: Role for evolutionary selection and environmental factors. [PDF]

PLoS Genetics, 2018
Selection pressure due to exposure to infectious pathogens endemic to Africa may explain distinct genetic variations in immune response genes. However, the impact of those genetic variations on human immunity remains understudied, especially within the ...
Song Yao, Chi-Chen Hong, Edward A Ruiz-Narváez, Sharon S Evans, Qianqian Zhu, Beverly A Schaefer, Li Yan, Marie V Coignet, Kathryn L Lunetta, Lara E Sucheston-Campbell, Kelvin Lee, Elisa V Bandera, Melissa A Troester, Lynn Rosenberg, Julie R Palmer, Andrew F Olshan, Christine B Ambrosone   +16 more
doaj   +1 more source

The uterine-chemokine-brain axis: menstrual cycle-associated symptoms (MCAS) are in part mediated by CCL2, CCL5, CCL11, CXCL8 and CXCL10

, 2023
The uterine-chemokine-brain axis: menstrual cycle-associated symptoms (MCAS) are in part mediated by CCL2, CCL5, CCL11, CXCL8 and ...
C Roomruangwong (13330680), A F Carvalho (13330368), Michael Maes (13055841), S Sirivichayakul (13330596)   +3 more
core  

Influence of Chemokine N-Terminal Modification on Biased Agonism at the Chemokine Receptor CCR1 [PDF]

, 2019
Leukocyte migration, a hallmark of the inflammatory response, is stimulated by the interactions between chemokines, which are expressed in injured or infected tissues, and chemokine receptors, which are G protein-coupled receptors (GPCRs) expressed in ...
Canals, Meritxell, Lane, Robert, Stone, Martin J., Sanchez, Julie   +3 more
core   +1 more source

Elevated Plasma Chemokines for Eosinophils in Neuromyelitis Optica Spectrum Disorders during Remission

Frontiers in Neurology, 2018
BackgroundA prominent pathological feature of neuromyelitis optica spectrum disorders (NMOSD) is markedly greater eosinophilic infiltration than that seen in other demyelinating diseases, like multiple sclerosis (MS).
Yanping Tong, Yanping Tong, Tao Yang, Tao Yang, Jingwen Wang, Tianyou Zhao, Lei Wang, Yuezhi Kang, Cuicui Cheng, Yongping Fan, Yongping Fan   +10 more
doaj   +1 more source