Results 41 to 50 of about 189,065 (308)

[Expression and clinical significance of chemokine CXCL10 and its receptor CXCR3 in hepatocellular carcinoma]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban, 2019
Zhang J, Chen J, Guan GW, Zhang T, Lu FM, Chen XM.   +5 more
europepmc   +2 more sources

CXCR3 and Heparin Binding Sites of the Chemokine IP-10 (CXCL10) [PDF]

Journal of Biological Chemistry, 2003
The chemokine IP-10 (interferon-inducible protein of 10 kDa, CXCL10) binds the G protein-coupled receptor CXCR3, which is found mainly on activated T cells and NK cells, and plays an important role in Th1-type inflammatory diseases. IP-10 also binds to glycosaminoglycans (GAGs), an interaction thought to be important for its sequestration on ...
Gabriele S V, Campanella, Elizabeth M J, Lee, Jieti, Sun, Andrew D, Luster   +3 more
openaire   +2 more sources

Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue [PDF]

, 2014
Five-year survival for patients with oral cancer has been disappointingly stable during the last decades, creating a demand for new biomarkers and treatment targets.
Philip John Coates, Torben Wilms, Laurell, Göran,, Rentoft, Matilda,, Coates, Philip John, Matilda Rentoft, Lotta Loljung, Göran Laurell, Karin Nylander, Rentoft, Matilda, Laurell, Göran, Wilms, Torben, Loljung, Lotta, Nylander, Karin, Loljung, Lotta,, Wilms, Torben,, Nylander, Karin,, Coates, Philip John,   +17 more
core   +1 more source

Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration

Nature Communications, 2021
The chemokine CXCL10 is associated with pathogenesis of cerebral malaria in Plasmodium falciparum infection. Here the authors show that P. falciparum produces extracellular vesicles laden with RNAs that are taken up by monocytes resulting in a RIG-I and ...
Yifat Ofir-Birin, Hila Ben Ami Pilo, Abel Cruz Camacho, Ariel Rudik, Anna Rivkin, Or-Yam Revach, Netta Nir, Tal Block Tamin, Paula Abou Karam, Edo Kiper, Yoav Peleg, Reinat Nevo, Aryeh Solomon, Tal Havkin-Solomon, Alicia Rojas, Ron Rotkopf, Ziv Porat, Dror Avni, Eli Schwartz, Thomas Zillinger, Gunther Hartmann, Antonella Di Pizio, Neils Ben Quashie, Rivka Dikstein, Motti Gerlic, Ana Claudia Torrecilhas, Carmit Levy, Esther N. M. Nolte-‘t Hoen, Andrew G. Bowie, Neta Regev-Rudzki   +29 more
doaj   +1 more source

New perspectives in vitiligo treatment [PDF]

Farmacja Polska, 2020
Vitiligo is a chronic depigmentation disease. It is characterized by damage or destruction of melanocytes (melanin-producing cells). The desease affects about 2% of population. The pathogenesis is complex and not fully understood.
Alicja Konieczna, Andrzej Winnicki, Jerzy Krysiński   +2 more
doaj   +1 more source

Mechanistic insights into SARS-CoV-2 spike protein induction of the chemokine CXCL10. [PDF]

Sci Rep
During a SARS-CoV-2 infection, macrophages recognize viral components resulting in cytokine production. While this response fuels virus elimination, overexpression of cytokines can lead to severe COVID-19. Previous studies suggest that the spike protein (
Ghazanfari D, Courreges MC, Belinski LE, Hogrell MJ, Lloyd J, C Bergmeier S, McCall KD, Goetz DJ.   +7 more
europepmc   +2 more sources

Lethal Nipah virus infection induces rapid overexpression of CXCL10. [PDF]

PLoS ONE, 2012
Nipah virus (NiV) is a recently emerged zoonotic Paramyxovirus that causes regular outbreaks in East Asia with mortality rate exceeding 75%. Major cellular targets of NiV infection are endothelial cells and neurons.
Cyrille Mathieu, Vanessa Guillaume, Amélie Sabine, Kien Chai Ong, Kum Thong Wong, Catherine Legras-Lachuer, Branka Horvat   +6 more
doaj   +1 more source

Data on the expression of CXCR3 ligands and pro-inflammatory cytokines in macrophages and CD4+ T cells after stimuli of CXCR3 ligands

Data in Brief, 2018
C-X-C motif chemokine receptor 3 (CXCR3) is a G protein-coupled receptor for three ligands which are C-X-C motif chemokine 9 (CXCL9), CXCL10, and CXCL11 [1]. Previously we have reported that CXCL10 promotes pro-inflammatory cytokine expression, and forms
Bongjun Kim, Jong-Ho Lee, Won Jong Jin, Hong-Hee Kim, Hyunil Ha, Zang Hee Lee   +5 more
doaj   +1 more source

Variation in Leishmania chemokine suppression driven by diversification of the GP63 virulence factor.

PLoS Neglected Tropical Diseases, 2021
Leishmaniasis is a neglected tropical disease with diverse outcomes ranging from self-healing lesions, to progressive non-healing lesions, to metastatic spread and destruction of mucous membranes.
Alejandro L Antonia, Alyson B Barnes, Amelia T Martin, Liuyang Wang, Dennis C Ko   +4 more
doaj   +1 more source

Technical Considerations and Confounders for Urine CXCL10 Chemokine Measurement

Transplantation Direct, 2019
Background. The urine C-X-C motif chemokine 10 (CXCL10) is a promising screening biomarker for renal allograft rejection. The aim of the study was to investigate important technical and biological aspects as well as potential confounders when measuring urine CXCL10. Methods.
Handschin J, Hirt-Minkowski P, Hönger G, Mitrovic S, Savic Prince S, Ho J, Nickerson P, Schaub S   +7 more
openaire   +3 more sources