Results 51 to 60 of about 189,065 (308)

Mediator MED23 regulates inflammatory responses and liver fibrosis.

PLoS Biology, 2019
Liver fibrosis, often associated with cirrhosis and hepatocellular carcinomas, is characterized by hepatic damage, an inflammatory response, and hepatic stellate cell (HSC) activation, although the underlying mechanisms are largely unknown. Here, we show
Zhichao Wang, Dan Cao, Chonghui Li, Lihua Min, Gang Wang   +4 more
doaj   +1 more source

The Opp (AmiACDEF) Oligopeptide Transporter Mediates Resistance of Serotype 2 Streptococcus pneumoniae D39 to Killing by Chemokine CXCL10 and Other Antimicrobial Peptides

Journal of Bacteriology, 2018
Antimicrobial peptides (AMPs), including chemokines, are produced during infections to kill pathogenic bacteria. To fill in gaps in knowledge about the sensitivities of Streptococcus pneumoniae and related Streptococcus species to chemokines and AMPs, we
K. Bruce, B. Rued, H. Tsui, M. Winkler
semanticscholar   +1 more source

CXCL10 levels in diagnosis and improved hemodynamics in patients with chronic thromboembolic pulmonary hypertension undergoing balloon pulmonary angioplasty

Pulmonary Circulation, 2022
Chronic thromboembolic pulmonary hypertension (CTEPH) is a progressive pulmonary vascular disease characterized by pulmonary artery stenosis or obstructions resulting from insufficient thrombus resolution.
Cheng Hong, Jianmin Lu, Riken Chen, Haimin Liu, Haiming Chen, Xiaofeng Wu, Wenliang Guo, Zijie Huang, Huizhao Liao   +8 more
doaj   +1 more source

CXCL10 in psoriasis [PDF]

, 2015
Chemokine (C-X-C motif) ligand (CXCL)10 is involved in the pathogenesis of psoriasis. It has been demonstrated that chemokine (C-X-C motif) receptors (CXCR)3 and CXCL10 were detected in keratinocytes and the dermal infiltrate obtained from active ...
Michele Colaci, FERRI, Clodoveo, Antonelli, Alessandro, COLACI, Michele, Ruffilli, Ilaria, Silvia Martina Ferrari, Clodoveo Ferri, Poupak Fallahi, Fallahi, Poupak, Alessandro Antonelli, FERRARI, Silvia Martina, Ilaria Ruffilli   +11 more
core   +1 more source

Spinal CXCL9 and CXCL11 are not involved in neuropathic pain despite an upregulation in the spinal cord following spinal nerve injury

Molecular Pain, 2018
Chemokines-mediated neuroinflammation in the spinal cord plays a critical role in the pathogenesis of neuropathic pain. Chemokine CXCL9, CXCL10, and CXCL11 have been identified as a same subfamily chemokine which bind to CXC chemokine receptor 3 to exert
Xiao-Bo Wu, Li-Na He, Bao-Chun Jiang, Hui Shi, Xue-Qiang Bai, Wen-Wen Zhang, Yong-Jing Gao   +6 more
doaj   +1 more source

Proinflammatory chemokine gene expression influences survival of patients with non-Hodgkin’s lymphoma

Folia Histochemica et Cytobiologica, 2011
The migration, survival and proliferation of cells is the basis for all physiologic and pathologic processes in the human body. All these reactions are regulated by a complex chemokine network that guides lymphocytes homing, chemotaxis, adhesion and ...
Kazimierz Kuliczkowski, Andrzej Lange, Tomasz Wróbel, Aleksandra Butrym, Dorota Dłubek, Ilona Kryczek, Emilia Jaskuła, Grzegorz Mazur   +7 more
doaj   +1 more source

Pancreatic Alpha-Cells Contribute Together With Beta-Cells to CXCL10 Expression in Type 1 Diabetes

Frontiers in Endocrinology, 2020
C-X-C Motif Chemokine Ligand 10 (CXCL10) is a pro-inflammatory chemokine specifically recognized by the ligand receptor CXCR3 which is mostly expressed in T-lymphocytes.
Laura Nigi, Laura Nigi, Noemi Brusco, Noemi Brusco, Giuseppina E. Grieco, Giuseppina E. Grieco, Giada Licata, Giada Licata, Lars Krogvold, Lars Krogvold, Lorella Marselli, Conny Gysemans, Lut Overbergh, Piero Marchetti, Chantal Mathieu, Knut Dahl Jørgensen, Knut Dahl Jørgensen, Guido Sebastiani, Guido Sebastiani, Francesco Dotta, Francesco Dotta, Francesco Dotta   +21 more
doaj   +1 more source

Interacting chemokine signals regulate dendritic cells in acute brain injury. [PDF]

PLoS ONE, 2014
Brain trauma is known to activate inflammatory cells via various chemokine signals although their interactions remain to be characterized. Mice deficient in Ccl3, Ccr2 or Cxcl10 were compared with wildtype mice after controlled cortical impact injury ...
Charlotte Israelsson, Annika Kylberg, Henrik Bengtsson, Lars Hillered, Ted Ebendal   +4 more
doaj   +1 more source

Assessment of CXCL10 Before and after narrow band UVB phototherapy in non-segmental vitiligo patients

Indian Journal of Dermatology, 2022
Background: Vitiligo is a common depigmenting skin disorder characterized by white macules and patches accompanied by local melanocyte loss, caused by autoimmune destruction.
Sherief M Hussein, Mohammed Abd El Hakim Sorour, Mahitab Samir, Shaimaa Ahmed Abd El Azim, Ahmed Hossain   +4 more
doaj   +1 more source

Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration

Molecular Neurodegeneration, 2017
Background Chemokine signalling is required for the homing of leukocytes during retinal inflammation, and is associated with pathogenesis of diseases such as age-related macular degeneration (AMD).
Riccardo Natoli, Nilisha Fernando, Michele Madigan, Joshua A. Chu-Tan, Krisztina Valter, Jan Provis, Matt Rutar   +6 more
doaj   +1 more source