Results 31 to 40 of about 189,065 (308)

New pairings and deorphanization among the atypical chemokine receptor family — physiological and clinical relevance

open access: yesFrontiers in Immunology, 2023
Atypical chemokine receptors (ACKRs) form a small subfamily of receptors (ACKR1–4) unable to trigger G protein-dependent signaling in response to their ligands.
Martyna Szpakowska   +10 more
doaj   +1 more source

HIV-1 Tat co-operates with IFN-gamma and TNF-alpha to increase CXCL10 in human astrocytes. [PDF]

open access: yesPLoS ONE, 2009
HIV-associated neurological disorders (HAND) are estimated to affect 60% of the HIV infected population. HIV-encephalitis (HIVE), the pathological correlate of the most severe form of HAND is often characterized by glial activation, cytokine/chemokine ...
Rachel Williams   +3 more
doaj   +1 more source

CXCR3 chemokine receptor ligands in sarcoidosis

open access: yesМедицинская иммунология, 2021
Sarcoidosis is a polysystemic inflammatory disease of unknown etiology, morphologically related to the group of granulomatosis, with heterogeneous clinical manifestations and outcomes.
N. M. Lazareva   +7 more
doaj   +1 more source

Levels of CXCL10 Chemokine in Dengue Infected Hepatocyte Huh 7 it-1 Cell Line Co-cultured with Peripheral Blood Mononuclear Cells

open access: yesMicrobiology Indonesia, 2020
Dengue is a mosquito borne virus that spreads rapidly in the world. At present, it is estimated that more than 3.9 billion people are at risk of being infected with dengue virus (DENV) and there are 96 million clinical cases that have been reported ...
BETI ERNAWATI DEWI   +3 more
doaj   +1 more source

Role of the transcription factor Fli-1 on the CXCL10/CXCR3 Axis*

open access: yesFrontiers in Immunology, 2023
The transcription factor Fli-1, a member of the ETS family of transcription factors, is implicated in the pathogenesis of lupus disease. Reduced Fli-1 expression in lupus mice leads to decreased renal Cxcl10 mRNA levels and renal infiltrating CXCR3+ T ...
Xuan Wang   +7 more
doaj   +1 more source

Toxicity and Structure of Antimicrobial Peptides Derived from the Chemokine, CXCL10 [PDF]

open access: yesBiophysical Journal, 2019
Peter Bailer   +5 more
openaire   +2 more sources

Screening of CXC chemokines in the microenvironment of ovarian cancer and the biological function of CXCL10 [PDF]

open access: yesWorld Journal of Surgical Oncology, 2021
Abstract Background This study aims to screen and identify the biological functions and prognostic value of CXC chemokines in ovarian cancer (OC) through bioinformatics and molecular biology methods, and to provide data support for the selection of biomarkers and prognostic analysis of OC ...
Weiyuan Li   +3 more
openaire   +3 more sources

REGULATION OF THE CXCL10 EXPRESSION AND INVESTIGATION OF THE RELATIONSHIPS OF THE CXCL10 DNA SEQUENCE VARIATION AND DISEASE

open access: yesSabiad, 2023
Objective: Chemokine proteins are significantly effective in inflammation and immunity. Chemokines are from the family of the chemokine proteins and they organise the leukocyte trafficking through the formation of chemotactic activity in the cells that ...
Hayriye Şentürk Çiftçi   +4 more
doaj   +1 more source

CXCL10 ( ) and CCL2 ( ) chemokines in systemic sclerosis a longitudinal study [PDF]

open access: yesRheumatology, 2008
To measure serum levels of CXCL10 and CCL2 chemokines in patients with SSc, and relate the findings to clinical phenotype and disease progression.Serum CXCL10 and CCL2 were assayed in 72 consecutive newly diagnosed SSc patients and in 72 sex- and age-matched controls. In 37 SSc and 37 controls, serum CXCL10 and CCL2 were re-evaluated 5 yrs later.SSc at
ANTONELLI, ALESSANDRO   +10 more
openaire   +2 more sources

Mouse CD8+ T Cell Migration in vitro and CXCR3 Internalization Assays

open access: yesBio-Protocol, 2017
Chemokines are molecules that regulate the positioning of cells during homeostasis and inflammation. CXCL10 is an interferon-induced chemokine that attracts cells that express the chemokine receptor CXCR3 on their surface.
Rosa Barreira da Silva, Matthew Albert
doaj   +1 more source

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