Results 91 to 100 of about 22,526 (176)

Elevated level of some chemokines in plasma of gastric cancer patients

Central European Journal of Immunology, 2017
Introduction : Gastric cancer is one of the most common cancer-related causes of death. This is mainly due to the lack of good noninvasive method/biomarkers suitable for early-tumour diagnosis and planning of further therapy modalities.
Monika Baj-Krzyworzeka, Kazimierz Węglarczyk, Jarek Baran, Antoni Szczepanik, Mirosław Szura, Maciej Siedlar   +5 more
doaj   +1 more source

Serum IFN-γ-inducible chemokines CXCL9 and CXCL10 are elevated in nonimmediate drug hypersensitivity reactions

Asian Pacific Journal of Allergy and Immunology, 2016
The recruitment to the skin of drug-responsive T cells is responsible for the inflammatory profiles of non-immediate drug hypersensitivity reactions (niDHRs). Maculopapular exanthema (MPE) and Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) have quite distinct T cell infiltrating patterns.To investigate serum levels of CXCL9, CXCL10 and
Fang, Wang, Renxin, Cai, Dingyang, He, Yukun, Zhao, Yanting, Ye, Xingqi, Zhang   +5 more
openaire   +2 more sources

Rapid biolayer interferometry measurements of urinary CXCL9 to detect cellular infiltrates noninvasively after kidney transplantation [PDF]

, 2019
Introduction: measuring the chemokine CXCL9 in urine by enzyme-linked immunosorbent assay (ELISA) can diagnose acute cellular rejection (ACR) noninvasively after kidney transplantation, but the required 12- to 24-hour turnaround time is not ideal for ...
Gandolfini, Ilaria, Purroy, Carolina, Abecassis, Michael, Florman, Sander, Harris, Cynthia, Bestard Matamoros, Oriol, Friedewald, John, La Manna, Gaetano, Maggiore, Umberto, Cravedi, Paolo, Cremaschi, Elena, Jarque, Marta, Shapiro, Ron, Anderson, Lisa, Moran, Thomas, Piotti, Giovanni, Nair, Vinay, Duty, J. Andrew, Comai, Giorgia, Heeger, Peter S., Reid-Adam, Jessica   +20 more
core   +1 more source

Chemokine microenvironment in primary central nervous system lymphoma [PDF]

, 2010
Primary central nervous system lymphomas (PCNSL) are aggressive extranodal malignancies confined to the central nervous system (CNS), mostly of diffuse large B cell histotype.
Venetz, Daniel
core   +1 more source

Core signature of rejection-associated cytokines and chemokines in endomyocardial biopsies after heart transplantation

Frontiers in Cardiovascular Medicine
BackgroundRejection remains a limiting factor for survival after heart transplantation (HTx), and predictive biomarkers are still missing. Therefore, we aimed to define the cytokine/chemokine microenvironment in endomyocardial biopsies (EMB) and plasma ...
Lena M.-L. Radomsky, Jenny F. Kühne, Kerstin Beushausen, Jana Keil, Ludmilla Knigina, Yves Scheibner, Adelheid Görler, Arjang Ruhparwar, Fabio Ius, Christoph L. Bara, Christine S. Falk, Christine S. Falk   +11 more
doaj   +1 more source

Association of Chemokine Genes CXCL9 and CXCL10 Polymorphisms with Tuberculosis in Pakistani Population

Pakistan Journal of Zoology, 2022
Saleha Tabassum, Muneeza Zafar, Munazza Raza Mirza, Muhammad Iqbal Choudhary, Ikram ul Haq, Imran Riaz Malik, Ambreen Ansari, Mehtab Alam   +7 more
openaire   +1 more source

Development of DPP-4-resistant CXCL9-Fc and CXCL10-Fc chemokines for effective cancer immunotherapy

Proceedings of the National Academy of Sciences
CXCR3 is a chemokine receptor for three ligands: CXCL9, CXCL10, and CXCL11. Accumulating evidence, including data presented here, suggests that the interaction between CXCL9/CXCL10 and CXCR3 not only attracts CXCR3+ T cells but also promotes the induction of IFNγ- high effector/cytotoxic CD4+ and CD8+ T cells ...
Jennie Lugassy, Noor Abdala-Saleh, Ghada Jarrous, Abeer Turky, Daniel Saidemberg, Gabriela Ridner-Bahar, Nir Berger, Dana Bar-On, Tetsuya Taura, David Wilson, Nathan Karin   +10 more
openaire   +3 more sources

Active learning-guided mechanistic modeling of CXCL9 regulation in pancreatic cancer [PDF]

Cold tumors like pancreatic cancer suffer from poor immune infiltration, limiting effective anti-tumor responses. The chemokine CXCL9 promotes immune cell recruitment, but the signaling mechanisms regulating its expression in tumor cells remain poorly ...
Yelleswarapu, V.S.M.K., Wang, B.; id_orcid, Descamps, L., Eduati, F.   +3 more
core   +1 more source

Regulation of cytokine and chemokine expression by histone lysine methyltransferase MLL1 in rheumatoid arthritis synovial fibroblasts

Scientific Reports
Histone lysine methylation is thought to play a role in the pathogenesis of rheumatoid arthritis (RA). We previously reported aberrant expression of the gene encoding mixed-lineage leukemia 1 (MLL1), which catalyzes methylation of histone H3 lysine 4 ...
Keita Okamoto, Yasuto Araki, Yoshimi Aizaki, Shinya Tanaka, Yuho Kadono, Toshihide Mimura   +5 more
doaj   +1 more source

Adeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade

Nature Communications
There are numerous mechanisms by which glioblastoma cells evade immunological detection, underscoring the need for strategic combinatorial treatments to achieve appreciable therapeutic effects.
Christina A. von Roemeling, Jeet A. Patel, Savannah L. Carpenter, Oleg Yegorov, Changlin Yang, Alisha Bhatia, Bently P. Doonan, Rylynn Russell, Vrunda S. Trivedi, Kelena Klippel, Daniel H. Ryu, Adam Grippin, Hunter S. Futch, Yong Ran, Lan B. Hoang-Minh, Frances L. Weidert, Todd E. Golde, Duane A. Mitchell   +17 more
doaj   +1 more source