Results 71 to 80 of about 22,526 (176)

The positively charged COOH-terminal glycosaminoglycan-binding CXCL9(74-103) peptide inhibits CXCL8-induced neutrophil extravasation and monosodium urate Crystal-induced Gout in Mice [PDF]

, 2015
The ELR(-)CXC chemokine CXCL9 is characterized by a long, highly positively charged COOH-terminal region, absent in most other chemokines. Several natural leukocyte- and fibroblast-derived COOH-terminally truncated CXCL9 forms missing up to 30 amino ...
Janssens, Rik, Kungl, Andreas J., Ronsse, Isabelle, Van Damme, Jo, Berghmans, Nele, Boff, Daiane, Proost, Paul, Vanheule, Vincent, Mortier, Anneleen, Amaral, Flavio Almeida, Kitic, Nikola, Teixeira, Mauro Martins   +11 more
core   +1 more source

The Chemokines CXCL9 and CXCL10 Promote a Protective Immune Response but Do Not Contribute to Cardiac Inflammation following Infection with Trypanosoma cruzi [PDF]

, 2006
The expression of chemokines within the heart during experimental infection of susceptible mice with the Colombiana strain of Trypanosoma cruzi was characterized in an attempt to determine a functional role for these molecules in both host defense and ...
Jerry E. Manning, Ruth A. Wrightsman, Manning, Jerry E, Thomas E. Lane, Hardison, Jenny L, Lane, Thomas E, Philip M. Carpenter, Wrightsman, Ruth A, Carpenter, Philip M, Jenny L. Hardison   +9 more
core   +1 more source

Sequential activation of conventional and plasmacytoid dendritic cells in autoimmune pancreatitis and systemic lupus erythematosus: similarities and dissimilarities

Frontiers in Immunology
Type 1 autoimmune pancreatitis (AIP) and systemic lupus erythematosus (SLE) are caused by type I IFNs secreted by plasmacytoid dendritic cells (pDCs).
Akane Hara, Tomohiro Watanabe, Kosuke Minaga, Ken Kamata, Warren Strober, Masatoshi Kudo   +5 more
doaj   +1 more source

SufA of the opportunistic pathogen Finegoldia magna modulates actions of the antibacterial chemokine MIG/CXCL9, promoting bacterial survival during epithelial inflammation. [PDF]

, 2009
The anaerobic bacterium Finegoldia magna is part of the human commensal microbiota, but is also an important opportunistic pathogen. This bacterium expresses a subtilisin-like serine-proteinase, SufA, which partially degrade the antibacterial chemokine ...
Olin, Anders I, Matthias Mörgelin, Mörgelin, Matthias, Karlsson, Christofer, Karlsson, Anna,, Olin, Anders, Christofer Karlsson, Malmsten, Martin, Karlsson, Christofer,, Eliasson, Mette, Karlsson, Anna, Eliasson, Mette,, Martin Malmsten, Frick, Inga-Maria,, Olin, Anders,, Arne Egesten, Egesten, Arne, Anna Karlsson, Mette Eliasson, Mörgelin, Matthias,, Anders I. Olin, Frick, Inga-Maria, Egesten, Arne,, Malmsten, Martin,, Inga-Maria Frick, Lund University.   +25 more
core   +1 more source

Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells. [PDF]

PLoS ONE, 2015
CD8+ T-cells are located in the small airways of COPD patients and may contribute to pathophysiology. CD8+ cells express the chemokine receptor, CXCR3 that binds CXCL9, CXCL10 and CXCL11, which are elevated in the airways of COPD patients.
Peter S Fenwick, Patricia Macedo, Iain C Kilty, Peter J Barnes, Louise E Donnelly   +4 more
doaj   +1 more source

Serum inflammatory mediators as markers of human Lyme disease activity. [PDF]

PLoS ONE, 2014
Chemokines and cytokines are key signaling molecules that orchestrate the trafficking of immune cells, direct them to sites of tissue injury and inflammation and modulate their states of activation and effector cell function.
Mark J Soloski, Lauren A Crowder, Lauren J Lahey, Catriona A Wagner, William H Robinson, John N Aucott   +5 more
doaj   +1 more source

Non-invasive Chemokine Detection: Improved Prediction of Antibody-Mediated Rejection in Donor-Specific Antibody-Positive Renal Allograft Recipients

Frontiers in Medicine, 2020
Background: Screening for donor-specific antibodies (DSA) has limited diagnostic value in patients with late antibody-mediated rejection (ABMR). Here, we evaluated whether biomarkers reflecting microcirculation inflammation or tissue injury—as an adjunct
Jakob Mühlbacher, Konstantin Doberer, Nicolas Kozakowski, Heinz Regele, Sümeyra Camovic, Susanne Haindl, Gregor Bond, Helmuth Haslacher, Farsad Eskandary, Jeff Reeve, Georg A. Böhmig, Markus Wahrmann   +11 more
doaj   +1 more source

Cure of chronic viral infection and virus-induced type 1 diabetes by neutralizing antibodies [PDF]

, 2009
The use of neutralizing antibodies is one of the most successful methods to interfere with receptor–ligand interactions in vivo. In particular blockade of soluble inflammatory mediators or their corresponding cellular receptors was proven an effective ...
Christen, Urs, Ejrnaes, Mette, Herrath, Matthias G. von   +2 more
core   +1 more source

A meta-analysis of chemokines in alopecia areata: recruiting immune cells toward the hair follicle

Frontiers in Immunology
A deeper understanding of the immune-based pathogenesis of alopecia areata is essential for the development of novel targeted therapies. Compared to cytokines, chemokines exhibit substantially higher serum concentrations, offering a more robust approach ...
Elise Van Caelenberg, Elise Van Caelenberg, Arno Belpaire, Arno Belpaire, Nanja van Geel, Nanja van Geel, Reinhart Speeckaert, Reinhart Speeckaert   +7 more
doaj   +1 more source

Association between CXCL9 and CXCL10 chemokine gene polymorphisms and acute graft rejection after liver transplantation [PDF]

, 2019
Akutno stanično odbacivanje (ASO) klinički je vrlo značajan događaj koji ugrožava preživljenje i presatka i primatelja jetre. Kemokini CXCL9/10 imaju ključnu ulogu u regrutiranju T-limfocita u presadak te su njihove povišene serumske vrijednosti povezane
Ostojić, Ana
core   +4 more sources