Results 61 to 70 of about 22,526 (176)

Circulatory Levels of C-X-C Motif Chemokine Ligands 1, 9, and 10 Are Elevated in Patients with Ischemic Stroke

Eurasian Journal of Medicine, 2019
Objective: Inflammation plays a significant role in the development of ischemic stroke. CXC chemokines play pleiotropic roles in prolonged leukocyte locomotion, astrocyte migration/activation, and neural attachment/sprouting in response to focal stroke ...
Masoud Amin, Alireza Vakilian, Mohammad Hossein Mahmoodi, Gholamhossein Hassanshahi, Soudeh Khanamani Falahati-pour, Maryam Rafiei Dolatabadi, Ali Esmaeili Nadimi   +6 more
doaj   +1 more source

Patients with Mixed Cryoglobulinemia and HCV Infection, in Presence or Absence of Autoimmune Thyroiditis, Have High Serum Levels of (CXC MOTIF) Ligand (CXCL)9 and CXCL11 Chemokines

European Journal of Inflammation, 2012
No data are present in the literature regarding chemokine (CXC motif) ligand (CXCL)9 and CXCL11 circulating levels in cryoglobulinemia associated with hepatitis C (MC+HCV), in presence/absence of autoimmune thyroiditis (AT).
A. Antonelli, P. Fallahi, S.M. Ferrari, S. Frascerra, A. Corrado, M. Colaci, A. Manfredi, M. Maccheroni, D. Sansonno, A.L. Zignego, M. Centanni, C. Ferri   +11 more
doaj   +1 more source

Overproduction of CXC chemokines CXCL1, CXCL9, CXCL10 and CXCL12 in β-thalassemia major or patients

Annals of Saudi Medicine, 2014
B-thalassemia major is one of the most frequent hematological genetic disorders, worldwide. Chemokines are the main components of the immune system and play fundamental roles in pathogenesis of inflammatory disorders. Therefore, the present study aimed to examine whether serum CXC chemokines are altered in b-thalassemia major patients.We enrolled 63 b ...
Hamid Najmaddini, Gholamhossein Hassanshahi, Hamid Ostadebrahimi, Hoda Barkhordari, Habibeh Mashayekhi, Mina Nazari, Mozhgan Moogooei, Yassin Safari Arababadi, Fatemeh Peighambari, Mojgan Noroozi Karimabad   +9 more
openaire   +3 more sources

Antimicrobial activity and regulation of CXCL9 and CXCL10 in oral keratinocytes [PDF]

, 2016
Chemokine (C-X-C motif) ligand (CXCL)9 and CXCL10 are dysregulated in oral inflammatory conditions, and it is not known if these chemokines target microorganisms that form oral biofilm.
Celentano, A, Porter, Stephen, Cirillo, N, Alison Marshall, MIGNOGNA, MICHELE DAVIDE, Antonio Celentano, Cirillo, Nicola, Michael McCullough, Mignogna, MD, Nicola Cirillo, Marshall, A, Marshall, Alison, Porter, S, McCullough, M, Stephen Porter, Celentano, Antonio, Mccullough, Michael, Michele D. Mignogna   +17 more
core   +1 more source

Defining a non-eosinophilic inflammatory subtype in COPD: the role of CXCL9 and type 1 immune responses

Frontiers in Immunology
BackgroundC–X–C motif chemokine ligand 9 (CXCL9) is induced by the interferon-γ response, and its receptor, C–X–C motif chemokine receptor 3, is a well-established marker of T-helper 1 (Th1) cells, which play an essential role in type 1 immune responses.
Yin Chengsheng, Song Jiacui, Takehiro Hasegawa, Ling Yao, Takami Kondo, Li Huiping   +5 more
doaj   +1 more source

The Antibacterial Chemokine MIG/CXCL9 Is Constitutively Expressed in Epithelial Cells of the Male Urogenital Tract and Is Present in Seminal Plasma. [PDF]

, 2008
The integrity of the urogenital tract against potentially invasive pathogens is important for the health of the individual, fertilization, and continuance of species.
Mattias Collin, Linge, Helena, Collin, Mattias, Bjartell, Anders, Giwercman, Aleksander, Anders Bjartell, Malm, Johan, Arne Egesten, Egesten, Arne, Helena M. Linge, Aleksander Giwercman, Johan Malm   +11 more
core   +1 more source

Quantifying spatial CXCL9 distribution with image analysis predicts improved prognosis of triple-negative breast cancer

Frontiers in Genetics
Background: The C-X-C motif chemokine ligand 9 (CXCL9) plays a pivotal role in tumor immunity by recruiting and activating immune cells. However, the relationship between CXCL9 expression and prognosis in triple-negative breast cancer (TNBC) is unclear ...
Xi Cao, Yu Song, Huanwen Wu, Xinyu Ren, Qiang Sun, Zhiyong Liang   +5 more
doaj   +1 more source

Inhibition of renal fibrosis with a human CXCL9‐derived glycosaminoglycan‐binding peptide

Clinical & Translational Immunology, 2022
Objectives Renal fibrosis accompanies all chronic kidney disorders, ultimately leading to end‐stage kidney disease and the need for dialysis or even renal replacement.
Fariba Poosti, Mohammad Ayodhia Soebadi, Helena Crijns, Alexandra De Zutter, Mieke Metzemaekers, Nele Berghmans, Vincent Vanheule, Maarten Albersen, Ghislain Opdenakker, Jo Van Damme, Ben Sprangers, Paul Proost, Sofie Struyf   +12 more
doaj   +1 more source

Urinary Chemokines CXCL9 and CXCL10 Are Non-Invasive Biomarkers of Kidney Transplant Rejection

Annals of Transplantation
BACKGROUND Rejection is the main cause of kidney allograft failure, and kidney biopsy is the criterion standard method to diagnose it. However, non-invasive techniques to detect kidney transplant rejection are necessary. This study aimed to evaluate urinary chemokines CXCL9 and CXCL10 as potential biomarkers of kidney transplant rejection and to ...
Mačionienė, Ernesta, Simanavičius, Martynas, Vitkauskaitė, Monika, Vickienė, Alvita, Staučė, Roberta, Vinikovas, Artūras, Miglinas, Marius   +6 more
openaire   +2 more sources

Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cells

Oncology Letters, 2017
Cathepsin B (CTSB) is a lysosomal cysteine protease that has been linked to the progression of breast cancer, for example by activation of other proteases and tumor-promoting cytokines, thereby supporting tumor invasion and metastasis. Previously, it was shown that CTSB cleaves and inactivates C-X-C motif chemokine receptor 3 (CXCR3) chemokines.
Bronger, Holger, Karge, Anne, Dreyer, Tobias, Zech, Daniela, Kraeft, Sara, Avril, Stefanie, Kiechle, Marion, Schmitt, Manfred   +7 more
openaire   +3 more sources