Results 41 to 50 of about 22,526 (176)

Differential expression of CXCL1, CXCL9, CXCL10 and CXCL12 chemokines in alopecia areata.

Iranian journal of immunology : IJI, 2013
Alopecia Areata (AA) is a non-scarring, autoimmune disorder which causes hair loss. Inflammatory reactions are involved in hair loss of the scalp and/or body. The involvement of chemokine receptors in the pathogenesis of AA is well defined among which, CXCL1 acts on neutrophils and CXCL9, CXCL10 and CXCL12 serve as T lymphocytes recruiters.To study the
Zainodini, Nahid, Hassanshahi, Gholamhossein, Kazemi Arababadi, Mohammad, Khorramdelazad, Hossein, Mirzaei, Afshin   +4 more
openaire   +2 more sources

CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation - A target for novel cancer therapy. [PDF]

, 2018
Chemokines are proteins which induce chemotaxis, promote differentiation of immune cells, and cause tissue extravasation. Given these properties, their role in anti-tumor immune response in the cancer environment is of great interest.
Puccini, Alberto, Madiha Naseem, Hideo Baba, Martin D Berger, Zhang, Wu, McSkane, Michelle, Soni, Shivani, Tokunaga, Ryuma, Ryuma Tokunaga, Alberto Puccini, Michelle McSkane, Naseem, Madiha, Lenz, Heinz-Josef, Wu Zhang, Baba, Hideo, Heinz-Josef Lenz, Berger, Martin Dave, Shivani Soni   +17 more
core   +1 more source

Interleukin-1β induces CXCR3-mediated chemotaxis to promote umbilical cord mesenchymal stem cell transendothelial migration

Stem Cell Research & Therapy, 2018
Background Mesenchymal stem cells (MSCs) are known to home to injured and inflamed regions via the bloodstream to assist in tissue regeneration in response to signals of cellular damage.
Yu-Chien Guo, Yun-Hsuan Chiu, Chie-Pein Chen, Hwai-Shi Wang   +3 more
doaj   +1 more source

Chemokine MCP1/CCL2 and RANTES/CCL5 gene polymorphisms influence Henoch-Schonlein purpura susceptibility and severity [PDF]

, 2017
Background/Purpose: Henoch-Schonlein purpura (HSP) is the most common small vessel vasculitis in children. It is considered to be an IgA-containing immune complex-mediated disease.
王麗潔;李志鴻;俞欣慧;江伯倫;楊曜旭;陳為堅, Yu, Hsin-Hui;Liu, Pi-Hua;Yang, Yao-Hsu;Lee, Jyh-Hong;Wang, Li-Chieh;Chen, Wei-J.;Chiang, Bor-Luen   +1 more
core   +1 more source

Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans [PDF]

, 2009
BACKGROUND & AIMS: Fibrosis is the hallmark of chronic liver diseases, yet many aspects of its mechanism remain to be defined. Chemokines are ubiquitous chemotactic molecules that mediate many acute and chronic inflammatory conditions, and CXC chemokine ...
Gaßler, Nikolaus, Dahl, Edgar, Berres, Marie-Luise, Moreno Zaldivar, Mirko, Streetz, Konrad Ludwig, Tacke, Frank, Wasmuth, Hermann E., Keppeler, Hildegard, Zimmermann, Henning, Weiskirchen, Ralf, Schmitz, Petra, Berg, Thomas, Lammert, Frank, Streetz, Konrad L., Zimmermann, Henning Wolfgang, Zaldivar, Mirko Moreno, Hillebrandt, Sonja, Trautwein, Christian, Friedman, Scott L., Scholten, David, Hellerbrand, Claus   +20 more
core   +1 more source

Exploring Immune Development in Infants With Moderate to Severe Atopic Dermatitis

Frontiers in Immunology, 2018
BackgroundAtopic dermatitis (AD) is the most common chronic inflammatory skin disease in infancy with a complex pathology. In adults, the clinical severity of AD has been associated with increases in T helper cell type (Th) 2, Th22, and Th17 serum ...
Lies Hulshof, Saskia A. Overbeek, Saskia A. Overbeek, Anne L. Wyllie, Mei Ling J. N. Chu, Debby Bogaert, Wilco de Jager, Leon M. J. Knippels, Leon M. J. Knippels, Elisabeth A. M. Sanders, Wim M. C. van Aalderen, Johan Garssen, Johan Garssen, Belinda van’t Land, Belinda van’t Land, Aline B. Sprikkelman, Aline B. Sprikkelman, The Clinical Study Group, A. Blauw, B. Dontje, Y. C. M. Duijvestein, W. H. C. de Boom, I. Groot, M. Boks, Y. van Kooyk, D. H. H. Fandri, D. Hijnen, M. A. Middelkamp-Hup, B. Papi, M. Roelofs, A. Rijnierse, D. Veening, Clinical Trial Support, B. J. Prakken, G. W. Ten Tusscher, R. A. Tupker, L. E. M. Willemsen   +36 more
doaj   +1 more source

Plasma chemokines CXCL10 and CXCL9 as potential diagnostic markers of drug-sensitive and drug-resistant tuberculosis

Scientific Reports, 2023
AbstractTuberculosis (TB) diagnosis still remains to be a challenge with the currently used immune based diagnostic methods particularly Interferon Gamma Release Assay due to the sensitivity issues and their inability in differentiating stages of TB infection.
Sampath, Pavithra, Rajamanickam, Anuradha, Kannan, T, Natarajan, Alangudi Palaniappan, Syeed Hissar, S., Dhanapal, Madhavan, Thangavelu, Bharathiraja, Jayabal, Lavanya, Murugesan, Ramesh P., Ranganathan, Uma Devi, Babu, Subash, Bethunaickan, Ramalingam   +11 more
openaire   +3 more sources

CXCL9 and CXCL10 predict survival and are regulated by cyclooxygenase inhibition in advanced serous ovarian cancer. [PDF]

, 2016
Tumour-infiltrating lymphocytes (TILs) are associated with improved survival in several epithelial cancers. The two chemokines CXCL9 and CXCL10 facilitate chemotactic recruitment of TILs, and their intratumoral accumulation is a conceivable way to ...
Bronger, Holger;Singer, Judith;Windmüller, Claudia;Reuning, Ute;Zech, Daniela;Delbridge, Claire;Dorn, Julia;Kiechle, Marion;Schmalfeldt, Barbara;Schmitt, Manfred;Avril, Stefanie
core   +1 more source

Highly Sensitive Immuno-CRISPR Assay for CXCL9 Detection [PDF]

, 2021
CRISPR-based detection of target DNA or RNA exploits a dual function, including target sequence-specific recognition followed by trans-cleavage activity of a collateral ssDNA linker between a fluorophore (F) and a quencher (Q), which amplifies a ...
Seok-Joon Kwon (16891), Seok-Joon Kwon, Mirco Sorci (351082), Mirco Sorci, Jonathan S. Dordick, Jonathan S. Dordick (62693), Peter S. Heeger, Peter S. Heeger (11792518), Inseon Lee (3951521), Inseon Lee   +9 more
core   +1 more source

CXCL9/10/11, a regulator of PD-L1 expression in gastric cancer

BMC Cancer, 2018
Background Programmed death-ligand 1 (PD-L1) is an immunosuppressor that plays an important role in cancer treatments. Although majority of the studies demonstrated that PD-L1 expression was regulated by cellular intrinsic and extrinsic controls, and IFN-
Chenlu Zhang, Zhi Li, Ling Xu, Xiaofang Che, Ti Wen, Yibo Fan, Ce Li, Shuo Wang, Yu Cheng, Xiaoxun Wang, Xiujuan Qu, Yunpeng Liu   +11 more
doaj   +1 more source