Results 51 to 60 of about 22,526 (176)

CXCL9, but not CXCL10, promotes CXCR3-dependent immune-mediated kidney disease [PDF]

, 2008
Chemokines are instrumental in macrophage- and T cell-dependent diseases. The chemokine CCL2 promotes kidney disease in two models of immune-mediated nephritis (MRL.-Faslpr mice and the nephrotoxic serum nephritis model), but evidence suggests that ...
Huang, XR, Lu, B, Kelley, VR, J. Menke, B. Lu, Luster, AD, Zeller, GC, V. R. Kelley, Menke, J, J. Farber, Kikawada, E, Farber, J, G. C. Zeller, X. R. Huang, A. D. Luster, H. Y. Lan, Lan, HY, E. Kikawada, T. K. Means, Means, TK   +19 more
core   +1 more source

CXCL9 is differentially expressed in central nervous system metastasis. [PDF]

, 2023
Metastasis to the brain occurs in a significant fraction of patients with breast cancer and lung cancer (1-3). We mined published RNA-sequencing and multiplexed gene expression data (4, 5), comparing primary and brain metastatic tumor transcriptomes for ...
Shahan Mamoor
core   +1 more source

CXCL9 as a key biomarker of vitiligo activity and prediction of the success of cultured melanocyte transplantation

Scientific Reports, 2021
This study aimed to investigate the potential biomarkers of vitiligo by evaluating the disease activity and curative effect of autologous cultured pure melanocyte transplantation (CMT) on patients. Altogether, 36patients with stable vitiligo were treated
Fuquan Lin, Wenting Hu, Wen Xu, Miaoni Zhou, Ai‑E. Xu   +4 more
doaj   +1 more source

The role of CXCL9, CXCL10, and CXCL13 chemokines in patients with Sjögren’s syndrome

Clinical Rheumatology
Sjögren's syndrome (SS) is a chronic, systemic, and autoimmune disease characterized by lymphocytic infiltration of all exocrine glands, primarily the lacrimal and salivary glands. Chemokines play a key role in many inflammatory diseases. They play a fundamental role in recruitment, transport, and activation of immune cells.
Hakbilen, Selda, Tezcan, Dilek, Eryavuz, Onmaz Duygu, Yılmaz, Sema, Körez, Muslu Kazım, Ünlü, Ali, Eryavuz Onmaz, Duygu   +6 more
openaire   +3 more sources

Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria [PDF]

Proceedings of the National Academy of Sciences, 2008
Cerebral malaria is a significant cause of global mortality, causing an estimated two million deaths per year, mainly in children. The pathogenesis of this disease remains incompletely understood. Chemokines have been implicated in the development of cerebral malaria, and the IFN-inducible CXCR3 chemokine ligand IP-10 (CXCL10) was recently
Gabriele S V, Campanella, Andrew M, Tager, Joseph K, El Khoury, Seddon Y, Thomas, Tabitha A, Abrazinski, Lindsay A, Manice, Richard A, Colvin, Andrew D, Luster   +7 more
openaire   +2 more sources

Negative regulation of eosinophil recruitment to the lung by the chemokine monokine induced by IFN-γ (Mig, CXCL9) [PDF]

Proceedings of the National Academy of Sciences, 2004
Experimental analysis of allergic airway inflammation (AAI) in animals and humans is associated with coordinate gene induction. Using DNA microarray analysis, we have identified a large panel of AAI signature genes. Unexpectedly, the allergen-challenged lung (a T helper 2 microenvironment) was found to be associated with the expression of T helper 1 ...
Fulkerson, Patricia C., Zimmermann, Nives, Yang, Ming, Foster, Paul S., Rothenberg, Marc E., Brandt, Eric B., Muntel, Emily E., Doepker, Matthew P., Kavanaugh, Jessica L., Mishra, Anil, Witte, David P., Zhang, Hongwei, Farber, Joshua M.   +12 more
openaire   +3 more sources

Urinary Chemokines CXCL9 and CXCL10 Are Noninvasive Markers of Renal Allograft Rejection and BK Viral Infection [PDF]

American Journal of Transplantation, 2011
Renal transplant recipients require periodic surveillance for immune-based complications such as rejection and infection. Noninvasive monitoring methods are preferred, particularly for children, for whom invasive testing is problematic. We performed a cross-sectional analysis of adult and pediatric transplant recipients to determine whether a urine ...
J A, Jackson, E J, Kim, B, Begley, J, Cheeseman, T, Harden, S D, Perez, S, Thomas, B, Warshaw, A D, Kirk   +8 more
openaire   +2 more sources

Identification of immune-related biomarkers associated with tumorigenesis and prognosis in cutaneous melanoma patients

Cancer Cell International, 2020
Background Skin cutaneous melanoma (SKCM) is one of the most malignant and aggressive cancers, causing about 72% of deaths in skin carcinoma. Although extensive study has explored the mechanism of recurrence and metastasis, the tumorigenesis of cutaneous
Biao Huang, Wei Han, Zu-Feng Sheng, Guo-Liang Shen   +3 more
doaj   +1 more source

Atorvastatin therapy reduces interferon-regulated chemokine CXCL9 plasma levels in patients with systemic lupus erythematosus [PDF]

, 2010
A recent study showed transcriptional levels of interferon-inducible chemokines in peripheral blood cells were associated with disease activity and organ damage in systemic lupus erythematosus, and may be useful in monitoring disease activity and ...
Teixeira, A. L., Ferreira, G. A., Sato, E. I. [UNIFESP]   +2 more
core   +1 more source

Association of the CXCL9-CXCR3 and CXCL13-CXCR5 axes with B-cell trafficking in giant cell arteritis and polymyalgia rheumatica [PDF]

, 2021
OBJECTIVE: B-cells are present in the inflamed arteries of giant cell arteritis (GCA) patients and a disturbed B-cell homeostasis is reported in peripheral blood of both GCA and the overlapping disease polymyalgia rheumatica (PMR).
Maria Sandovici, Abdulahad, Wayel; id_orcid, van der Geest, Kornelis S M, van der Geest, Kornelis S M; id_orcid, Graver, Jacoba C, Heeringa, Peter; id_orcid, Brouwer, Elisabeth, Peter Heeringa, Wayel Abdulahad, Kornelis S.M. van der Geest, Elisabeth Brouwer, Heeringa, Peter, Boots, Annemieke M H, Sandovici, Maria; id_orcid, Jacoba C. Graver, Annemieke M.H. Boots, Abdulahad, Wayel, Sandovici, Maria, Graver, Jacoba C; id_orcid   +18 more
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