Development of a new HISCL automated CXCL9 immunoassay [PDF]
Scientific Reports, 2023 C–X–C motif chemokine ligand 9 (CXCL9), a candidate biomarker, reflects type 1 (T1) inflammation pathology. Here, we report the analytical performance and clinical characteristics of a new CXCL9 reagent for a fully automated immunoassay device.
Takehiro Hasegawa +13 more
doaj +2 more sources
Non-invasive determination of disease activity in Crohn’s disease by serum luminex profiling [PDF]
Scientific ReportsCrohn’s disease (CD) is a type of inflammatory bowel disease (IBD), and treatment depends on disease activity assessment requiring invasive procedures. We aimed to identify serum cytokines/chemokines that differ between CD and controls, and by clinical ...
Gabriella A. Raffa +12 more
doaj +2 more sources
Homoeriodictyol, targeting the bitter taste receptor TAS2R14, lowers the secretion of pro-inflammatory chemokines upon treatment with SARS-CoV-2 peptide pools in human peripheral blood mononuclear cells [PDF]
Frontiers in ImmunologyExcessive cytokine production is a major complication in severe COVID-19. Treatment with antiviral drugs often elicits a bitter taste through activation of bitter taste receptors (TAS2Rs).
Barbara Danzer +5 more
doaj +2 more sources
Vagus nerve modulates acute-on-chronic liver failure progression via CXCL9 [PDF]
Chinese Medical Journal. Background:. Hepatic inflammatory cell accumulation and the subsequent systematic inflammation drive acute-on-chronic liver failure (ACLF) development. Previous studies showed that the vagus nerve exerts anti-inflammatory activity in many inflammatory
Li Wu +5 more
doaj +2 more sources
Frontiers in ImmunologyChemokines are cytokines that mediate leukocyte traffic between the lymphoid organs, the bloodstream, and the site of tissue damage, which is essential for an efficient immune response.
Natalia Valdés +7 more
doaj +4 more sources
Frontiers in Oncology, 2023 BackgroundThe C-X-C motif chemokine ligand-9 (CXCL9) is related to the progression of multiple neoplasms. Yet, its biological functions in uterine corpus endometrioid carcinoma (UCEC) remain shrouded in confusion.
Shen Xue +3 more
doaj +1 more source
The chemokine fragment CXCL9(74–103) diminishes neutrophil recruitment and joint inflammation in antigen-induced arthritis [PDF]
, 2018 This study investigates if treatment with a peptide corresponding to the 30 C-terminal amino acids of CXCL9, CXCL9(74–103), ameliorates joint inflammation in a murine model of antigen-induced arthritis (AIA).
Daiane Boff +8 more
core +3 more sources
Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a TNFR1 dependent manner [PDF]
Scientific Reports, 2016 AbstractProgranulin (PGRN), a pleiotrophic growth factor, is known to play an important role in the maintenance and regulation of the homeostatic dynamics of normal tissue development, proliferation, regeneration and host-defense. PGRN also has potent anti-inflammatory functionality and deregulated PGRN is associated with rheumatoid arthritis and ...
Jyoti Joshi Mundra +3 more
openaire +2 more sources
Immune Checkpoint Blockade Enhances Immune Activity of Therapeutic Lung Cancer Vaccine
Vaccines, 2020 Background: Immune checkpoint blockade that downregulates T cell evasion for effective immunity has provided a renewed interest in therapeutic cancer vaccines.
Pournima Kadam +5 more
doaj +1 more source
Chemokine and chemokine receptor expression in myocardium from patients bearing the CXCL9 and CXCL10 SNPs. [PDF]
, 2012 Expression of chemokines and chemokine receptors in myocardium samples from patients bearing the CXCL9 rs10336 SNP (A). Expression of chemokines and chemokine receptors in myocardium samples from patients bearing CXCL10 rs3921 SNP (B).
Eduardo Donadi (124970) +19 more
core +1 more source