Results 231 to 240 of about 369,183 (362)

Cluster of differentiation 133 (CD133) and C-X-C chemokine receptor 4 (CXCR4) associated with the incidence of metastasis in osteosarcoma patients. [PDF]

Eur J Orthop Surg Traumatol
Bimantara NG, Kamal AF, Wu PK, Wiratnaya IGE, Herqutanto H, Kurniawan A, Prabowo Y, Irsan II, Irawan NSB, Siregar NC.   +9 more
europepmc   +1 more source

Chemokine Receptors CXCR-1/2 Activate Mitogen-activated Protein Kinase via the Epidermal Growth Factor Receptor in Ovarian Cancer Cells [PDF]

, 2000
Gita Venkatakrishnan, Ravi Salgia, Jerome E. Groopman   +2 more
openalex   +1 more source

Enhancing the Effectiveness of Chemotherapy in Osteosarcoma by Targeting Tumour‐Associated Macrophages (TAMs) through STING Activation

Advanced Therapeutics, EarlyView.
Osteosarcoma isa highly aggressive bone cancer with an immunosuppressive tumor microenvironment that limits immunotherapy. This study explores STING pathway activation to reprogram tumor‐associated macrophages into a tumoricidal M1‐like phenotype and enhance doxorubicin efficacy. Results show that doxorubicin alone failed to activate the STING pathway,
Jordan C. O'Donoghue, Amanda Guitián‐Caamaño, Maeve Boyce, Fiona E. Freeman   +3 more
wiley   +1 more source

Prognostic impact and landscape of cellular CXCR5 chemokine receptor expression in clear-cell renal cell carcinoma. [PDF]

Cancer Immunol Immunother
Arai M, Tanaka N, Takamatsu K, Murakami T, Mikami S, Imamura T, Nakamura K, Nishihara H, Oya M.   +8 more
europepmc   +1 more source

CHOOSING RATIONAL COMBINATIONS OF THERAPEUTIC AGENTS: CONTRASTING EFFECTS OF COSTIMULATION BLOCKADE PLUS RAPAMYCIN OR CYCLOSPORIN ON INTRAGRAFT EXPRESSION OF CHEMOKINES, CHEMOKINE RECEPTORS AND APOPTOTIC GENES.

, 1999
Peter Topham, Y Li, T B Strom, Wayne W. Hancock   +3 more
openalex   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

Molecular basis of promiscuous chemokine binding and structural mimicry at the C-X-C chemokine receptor, CXCR2. [PDF]

Mol Cell
Saha S, Sano FK, Sharma S, Ganguly M, Mishra S, Dalal A, Akasaka H, Kobayashi TA, Zaidi N, Tiwari D, Roy N, Yadav MK, Banerjee N, Saha S, Mohapatra S, Itoh Y, Chevigné A, Banerjee R, Shihoya W, Nureki O, Shukla AK.   +20 more
europepmc   +1 more source

Cutting Edge: Identification of a Novel Chemokine Receptor That Binds Dendritic Cell- and T Cell-Active Chemokines Including ELC, SLC, and TECK [PDF]

, 2000
Jennifa Gosling, Daniel J. Dairaghi, Yu Wang, Michael R. Hanley, Dale Talbot, Zhenhua Miao, Thomas J. Schall   +6 more
openalex   +1 more source

ST6GAL1‐Mediated Sialylation Stabilizes PD‐L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer

Advanced Science, EarlyView.
ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu, Jingyi Liu, Wei Qin, Chengsheng Ding, Zhenghao Cai, Duohuo Shu, Hao Zhong, Yanyan Hu, Mengqin Yu, Leqi Zhou, Jianwen Li, Minhua Zheng, Bin Li, Sen Zhang, Xiao Yang, Bo Feng   +15 more
wiley   +1 more source

Design, Synthesis and Pharmacological Characterization of the First Photoswitchable Small-Molecule Agonist for the Atypical Chemokine Receptor 3. [PDF]

ACS Omega
Bérenger S, Adamska JM, Deflorian F, de Graaf C, Palmer CB, Szpakowska M, Chevigné A, de Esch IJP, Zarzycka B, Vischer HF, Wijtmans M, Leurs R.   +11 more
europepmc   +1 more source