Results 131 to 140 of about 48,525 (279)
Structure Modeling of the Chemokine Receptor CCR5: Implications for Ligand Binding and Selectivity [PDF]
, 2002 Marta Paterlini
openalex +1 more source
Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies
MedComm, Volume 7, Issue 2, February 2026.The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu +6 more
wiley +1 more source
Chemokine receptor CCR5: insights into structure, function, and regulation
Cellular Signalling, 2004 CC chemokine receptor 5 (CCR5) is a seven-transmembrane, G protein-coupled receptor (GPCR) which regulates trafficking and effector functions of memory/effector T-lymphocytes, macrophages, and immature dendritic cells. It also serves as the main coreceptor for the entry of R5 strains of human immunodeficiency virus (HIV-1, HIV-2).
openaire +3 more sources
Virology Journal, 2006 Background HIV-1 entry into cells is a multifaceted process involving target cell CD4 and the chemokine receptors, CXCR4 or CCR5. The lipid composition of the host cell plays a significant role in the HIV fusion process as it orchestrates the appropriate
Puri Anu +5 more
doaj +1 more source
Chemokine receptor CCR5 genotype influences the kinetics of human immunodeficiency virus type 1 infection in human PBL-SCID mice [PDF]
, 1997 Gastón Picchio +2 more
openalex +1 more source
Deciphering the Transcriptomic Signatures of Aging Across Organs in Mice
Aging Cell, Volume 25, Issue 2, February 2026.Comprehensive transcriptomic profiling of eight mouse organs across six ages reveals how aging reshapes biological processes. Trajectory and network analyses distinguish shared and organ‐specific signatures, charting the molecular landscape of systemic aging.
Sarah Morsy +9 more
wiley +1 more source
Frequency of CCR5?32 Variant in North-West of Iran [PDF]
Journal of Sciences, Islamic Republic of Iran, 2009 Chemokine and chemokine receptors show several variations which may affect resistance to infectious disease. A 32 base pair deletion in the open reading frame of the human CCR5 gene (CCR5?32) results in producing a truncated antigen which fails to be ...
D. Omrani
doaj
Enrichment of CXCR3+ CCR5+ T Cells in Human Tuberculosis: Hierarchy of Chemokine Receptors and Their Ligands [PDF]
, 2010 Pradip Saha +3 more
openalex +1 more source
Hevin Promotes Aging‐Related Cardiac Dysfunction via Facilitating Cardiac Inflammation in Male Mice
Aging Cell, Volume 25, Issue 2, February 2026.Hevin released by iWAT into circulation stimulates cardiac macrophages through TLR4, inducing their polarization and CCL5 secretion, leading to worsened cardiac dysfunction and subsequent recruitment of additional inflammatory cells for pro‐inflammatory factor release.
Shi‐Yu Huang +4 more
wiley +1 more source