Results 211 to 220 of about 258,666 (269)

A human cerebral organoid model of West Nile virus encephalitis shows innate immunocompetency. [PDF]

Nat Commun
Steffen JF, Widerspick L, Jansen S, Tappe D.   +3 more
europepmc   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Thykamine™: A New Player in the Field of Anti-Inflammatory Drugs. [PDF]

Biomedicines
Lynde C, Flamand L, McCarty V, Sampalis J.   +3 more
europepmc   +1 more source

Sex differences in disease severity and immune responses in murine and human inflammatory arthritis. [PDF]

Biol Sex Differ
Hemshekhar M, O'Neil LJ, Kahia N, Marshall CL, Singh T, Navarrete M, El-Gabalawy H, Mookherjee N, Arsenio J.   +8 more
europepmc   +1 more source

The distinct contribution of sternotomy to the systemic inflammatory response during children's heart surgery. [PDF]

Front Immunol
Bierer JD, Paffile J, Stanzel R, Henderson M, Sapp J, Andreou P, Marshall JS, Horne D.   +7 more
europepmc   +1 more source

Oral and Intranasal Administration of Polydeoxyribonucleotide Isolated from <i>Porphyra</i> sp. Ameliorates Acute Lung Injury via Suppressing Proinflammatory Cytokine Production in Mice. [PDF]

Curr Issues Mol Biol
Lee GY, Lee WS, Han J, Yoo YC.
europepmc   +1 more source

TRPA1 as a Key Regulator of Keratinocyte Homeostasis and Inflammation in Human Skin. [PDF]

Cells
Cattani C, Scarponi C, Morelli M, Eyerich K, Eyerich S, Napoli C, Madonna S, Albanesi C, Cavani A, Scopelliti F.   +9 more
europepmc   +1 more source

CXCL9 and CXCL10 support the exacerbated humoral response in recovered COVID-19 patients who developed acute respiratory distress syndrome by promoting plasma cell differentiation, whereas CXCL9 also induces CD40L and CXCR3 upregulation on T helper cells. [PDF]

Front Immunol
Quiroga R, Sanhueza S, Sepúlveda C, Antilef B, Muñoz C, Cabrera C, Fraga M, Llerena F, Lamperti L, Barría MI, Colombo A, Labarca G, Henríquez-Beltrán M, Ferrada L, Nova-Lamperti E.   +14 more
europepmc   +1 more source