Results 21 to 30 of about 258,666 (269)

The role of chemokines in Schistosoma mansoni infection: insights from human disease and murine models

Memorias do Instituto Oswaldo Cruz, 2006
Chemokines are a superfamily of low-molecular-weight cytokines that were initially described for their chemoattractant activity. It is now clear chemokines have several other activities that modulate immune processes.
Adriano LS Souza, Silvio R Sousa-Pereira, Mauro M Teixeira, José R Lambertucci, Antonio L Teixeira   +4 more
doaj   +1 more source

Higher expression of monocyte chemotactic protein 1 in mild COVID-19 patients might be correlated with inhibition of Type I IFN signaling

Virology Journal, 2021
Background Chemokine levels in severe coronavirus disease 2019 (COVID-19) patients have been shown to be markedly elevated. But the role of chemokines in mild COVID-19 has not yet been established. According to the epidemiological statistics, most of the
Xueyan Xi, Yang Guo, Min Zhu, Yuhui Wei, Gang Li, Boyu Du, Yunfu Wang   +6 more
doaj   +1 more source

Dendritic cell-targeting chemokines inhibit colorectal cancer progression

Exploration of Targeted Anti-tumor Therapy, 2022
Aim: Recent progress in cancer immunotherapy has shown its promise and prompted researchers to develop novel therapeutic strategies. Dendritic cells (DCs) are professional antigen-presenting cells crucial for initiating adaptive anti-tumor immunity ...
Pengkun Yuan, Yunyi Zhou, Zhixue Wang, Liming Gui, Bin Ma   +4 more
doaj   +1 more source

Monocyte Chemotactic Protein-1 (MCP1) Accumulation in Human Osteoclast Precursor Cultures

Life, 2022
In vitro osteoclast methods require constant treatment with macrophage colony stimulating factor (M-CSF) to support precursor survival and addition of the differentiation agent receptor activator of NF-κB ligand (RANKL).
Nigel A. Morrison, Mark R. Forwood
doaj   +1 more source

Functional expression of CCL8 and its interaction with chemokine receptor CCR3

BMC Immunology, 2017
Background Chemokines and their cognate receptors play important role in the control of leukocyte chemotaxis, HIV entry and other inflammatory diseases.
Baosheng Ge, Jiqiang Li, Zhijin Wei, Tingting Sun, Yanzhuo Song, Naseer Ullah Khan   +5 more
doaj   +1 more source

Understanding the mechanistic and therapeutic perspectives on cytokines and chemokines in acute high-altitude illness syndromes

Journal of Pharmaceutical Analysis
Acute high-altitude (HA) illnesses (AHAIs), including acute mountain sickness (AMS), HA cerebral edema (HACE), and HA pulmonary edema (HAPE), represent significant health challenges for individuals rapidly ascending to high altitudes.
Amin Ullah, Rajeev K. Singla, Yingbo Zhang, ShanShan Hu, Bairong Shen   +4 more
doaj   +1 more source

Expression of C–C motif chemokines and their receptors in bovine placentomes at spontaneous and induced parturition

The Journal of Reproduction and Development, 2019
In bovine placentomes, the inflammatory response is considered important for the detachment of the fetal membrane from the caruncle after parturition. Glucocorticoids, a trigger of the onset of parturition, facilitate functional maturation of placentomes
Hiroki HIRAYAMA, Ryosuke SAKUMOTO, Keisuke KOYAMA, Taichi YASUHARA, Taito HASEGAWA, Ryo INABA, Takashi FUJII, Akira NAITO, Satoru MORIYASU, Soichi KAGEYAMA   +9 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

THE ROLE OF CHEMOKINES IN FIBROMYALGIA

Rheumatology Quarterly
Aim: Chemokines are cytokines that cause chemotaxis to leukocytes and stem cells in inflammation and homeostasis. Fibromyalgia (FM) is characterized by widespread chronic pain and somatic symptoms. The role of immun mediators in the pathogenesis of FM is
Tuba Tülay Koca, Muhammed Seyithanoğlu, Fırat Sakınmaz   +2 more
doaj   +1 more source

Differential regulation of C-C chemokines during fibroblast-monocyte interactions: adhesion vs. inflammatory cytokine pathways

Mediators of Inflammation, 1998
The cell-to-ce ll interactions during chronic inflammatory diseases likely contribute to leukocyte accumulation leading to increased pathology and organ dys -function.
C. Zickus, S. L. Kunkel, K. Simpson, H. Evanoff, M. Glass, R. M. Strieter, N. W. Lukacs   +6 more
doaj   +1 more source