Results 51 to 60 of about 58,026 (240)

Re: Chemokines in Cancer [PDF]

open access: yes, 2016
Chemokines are chemotactic cytokines that regulate the trafficking and positioning of cells by activating the seven-transmembrane spanning G protein-coupled chemokine receptors (GPCR) or non G protein-coupled seven-transmembrane spanning receptors called
Fehmi Narter
core   +1 more source

Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection. [PDF]

open access: yesPLoS Pathogens, 2010
Chemokines have been found to exert direct, defensin-like antimicrobial activity in vitro, suggesting that, in addition to orchestrating cellular accumulation and activation, chemokines may contribute directly to the innate host response against ...
Matthew A Crawford   +7 more
doaj   +1 more source

Novel CXCR2â dependent liver regenerative qualities of ELRâ containing CXC chemokines [PDF]

open access: yes, 1999
Severe acute liver injury due to accidental or intentional acetaminophen overdose presents a major clinical dilemma often requiring liver transplantation.
Lukacs, Nicholas W.   +15 more
core   +1 more source

Additional file 2 of Screening of CXC chemokines in the microenvironment of ovarian cancer and the biological function of CXCL10 [PDF]

open access: yes, 2021
Additional file 2: Supplementary Figure 1. Oncomine database analysis of the expression of different chemokines. Supplementary Figure 2. The prognostic value of different expressed CXC chemokines in OC patients in the disease free survival curve ...
Weiyuan Li (9619499)   +3 more
core   +1 more source

Overexpression of the duffy antigen receptor for chemokines (DARC) by NSCLC tumor cells results in increased tumor necrosis

open access: yesBMC Cancer, 2004
Background The Duffy antigen receptor for chemokines (DARC) is known to be a promiscuous chemokine receptor that binds a variety of CXC and CC chemokines in the absence of any detectable signal transduction events.
Burdick Marie D   +3 more
doaj   +1 more source

Prognostic Significance and Therapeutic Target of CXC Chemokines in the Microenvironment of Lung Adenocarcinoma

open access: yesInternational Journal of General Medicine, 2022
Kun Wang, Rongyang Li, Yu Zhang, Weifeng Qi, Tao Fang, Weiming Yue, Hui Tian Department of Thoracic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, People’s Republic of ChinaCorrespondence: Hui Tian ...
Wang K   +6 more
doaj  

TRIM proteins and CXS chemokines : evolutionary dynamics and functional characterization of two large protein families in teleost fish [PDF]

open access: yes, 2012
Two large protein families with roles in the immune system were the subject of this thesis. In part one of the thesis, TRIM proteins were studied, which are part of an ancient intracellular immune system. In mammals, TRIM proteins were recently found to
van der Aa, L.M., Aa, L.M., van der
core  

A comprehensive bioinformatics analysis to identify potential prognostic biomarkers among CC and CXC chemokines in breast cancer

open access: yesScientific Reports, 2022
Breast cancer (BC) is a major human health problem due to its increasing incidence and mortality rate. CC and CXC chemokines are associated with tumorigenesis and the progression of many cancers.
Hossein Hozhabri   +3 more
doaj   +1 more source

Interleukin-6-Production Is Responsible for Induction of Hepatic Synthesis of Several Chemokines as Acute-Phase Mediators in Two Animal Models: Possible Significance for Interpretation of Laboratory Changes in Severely Ill Patients

open access: yesBiology, 2022
A mild to moderate increase in acute-phase proteins (APPs) and a decrease in serum albumin levels are detected in hospitalized COVID-19 patients. A similar trend is also observed for acute-phase cytokines (APC), mainly IL6, besides chemokines (e.g ...
Ihtzaz Ahmed Malik, Giuliano Ramadori
doaj   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

open access: yesAdvanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang   +10 more
wiley   +1 more source

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