Results 51 to 60 of about 56,569 (202)
Chemokines and glioma: Invasion and more
, 2010 Increasing pieces of evidence indicate that the chemokine system influences several aspects of brain physiology and pathology. A deregulated chemokine expression pattern is observed during neurological diseases, including multiple sclerosis and brain ...
BERNARDINI, Giovanni +5 more
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
BiomoleculesCell migration capacity represents an essential function of the immune system. Pregnancy involves numerous morphogenetic events, angiogenesis, the establishment of intercellular connections, and complex interactions between maternal and fetal immune ...
Julia A. Shevchenko +2 more
doaj +1 more source
Prostate Cancer: The role of inflammation and chemokines
, 2019 Prostate cancer (PC) is a leading cause of death in men. Inflammation is one of the initiating processeswhereby cells are trafficked into the tumor microenvironment by specific cytokines termed chemokines.
Prokar Dasgupta +8 more
core +1 more source
Abdominal and Pelvic Organ Failure Induced by Intraperitoneal Influenza A Virus Infection in Mice
Frontiers in Microbiology, 2020 In humans, respiratory infections with influenza A viruses can be lethal, but it is unclear whether non-respiratory influenza A infections can be equally lethal.
Avishekh Gautam +13 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Advances in chemokines of teleost fish species
Aquaculture and FisheriesIn mammals, chemokines are a superfamily of cytokines that regulate cell migration or exert direct antimicrobial activity. The presence and organization of four invariant cysteine residues within the mature protein sequence can classify chemokines into ...
Hongsen Xu, Fuguo Liu
doaj +1 more source
Complex role of chemokine mediators in animal models of Alzheimer's Disease
Biomedical Journal, 2018 Chemokines are a family of cytokines, first described to play a role in the immune system. However, neurons and glial cells also express chemokines and their receptors.
Elodie Martin, Cécile Delarasse
doaj +1 more source
Stem Cells Translational Medicine, 2021 Nakajo‐Nishimura syndrome (NNS) is an autoinflammatory disorder caused by a homozygous mutations in the PSMB8 gene. The administration of systemic corticosteroids is partially effective, but continuous treatment causes severe side effects.
Naoya Kase +8 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source