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Viral Chemokine Receptors [PDF]

open access: yesFrontiers in Immunology, 2015
When my lab sequenced the first chemokine receptors CXCR2 and CCR1 in 1991, the top BLAST hit for CCR1 was open reading frame (ORF) US28 of human cytomegalovirus (HCMV), indicating an obvious common ancestor and a possible example of gene piracy. Pox virologists had already identified virally encoded TNF and IFN-γ binding proteins, copied from the host
Philip eMurphy
doaj   +3 more sources

Structural biology of chemokine receptors

open access: yesBiological Research, 1999
Chemokine receptors are G protein-coupled receptors that mediate migration and activation of leukocytes as an important part of a protective immune response to injury and infection.
DANIEL ROJO   +2 more
doaj  

Targeting Chemokines and Chemokine Receptors in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

open access: yesJournal of Inflammation Research, 2020
Sarah Dhaiban, Mena Al-Ani, Noha Mousaad Elemam, Azzam A Maghazachi College of Medicine and Immuno-Oncology Group, Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab EmiratesCorrespondence: Azzam A MaghazachiDepartment of
Dhaiban S   +3 more
doaj  

Glycosaminoglycan Interactions with Chemokines Add Complexity to a Complex System

open access: yesPharmaceuticals, 2017
Chemokines have two types of interactions that function cooperatively to control cell migration. Chemokine receptors on migrating cells integrate signals initiated upon chemokine binding to promote cell movement.
Amanda E. I. Proudfoot   +3 more
doaj   +1 more source

The role of chemokines in acute liver injury

open access: yesFrontiers in Physiology, 2012
Chemokines are small molecular weight proteins primarily known to drive migration of immune cells populations. In both acute and chronic liver injury, hepatic chemokine expression is induced resulting in inflammatory cell infiltration, angiogenesis, and ...
Yedidya eSaiman, Scott L. Friedman
doaj   +1 more source

Hyaluronic acid alters vessel behavior in CXCL12-treated HUVECs [PDF]

open access: yes, 2018
Hyaluronic acid (HA) is a key component of the extracellular matrix known for absorbing water, swelling, and altering solid stress of tumors. HA’s anionic behavior may provide important biochemical effects toward tumor progression as well.
Seibel, Alex J.
core  

Innate immune response in avian macrophages elicited by Chlamydia psittaci [PDF]

open access: yes, 2015
Chlamydia psittaci is a gram-negative, obligate, intracellular bacterium, which mainly infects birds and mammals. Not much is known about innate immunity initiated by C. psittaci.
Lagae, Stefanie, Vanrompay, Daisy
core  

Role of Chemokines and Chemokine Receptors in Rheumatoid Arthritis

open access: yesImmunoTargets and Therapy, 2020
Noha Mousaad Elemam,1 Suad Hannawi,2 Azzam A Maghazachi1 1College of Medicine and Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates; 2Ministry of Health and Prevention, Department of Rheumatology, Dubai, United ...
Elemam NM, Hannawi S, Maghazachi AA
doaj  

Host factors and early treatments to restrict paediatric HIV infection and early disease progression [PDF]

open access: yes, 2015
open6noA body of evidence indicates that a threshold level of the virus is required to establish systemic and persistent HIV infection in the host and that this level depends on virus-host interactions.
De Rossi, Anita   +5 more
core   +1 more source

Chemokines and chemokine receptors in Behçet's disease. [PDF]

open access: yesFront Immunol, 2023
Li Z, Cheng L, Zhan H, Li Y.
europepmc   +1 more source

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