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PET Imaging Radiotracers of Chemokine Receptors [PDF]

open access: yesMolecules, 2021
Chemokines and chemokine receptors have been recognized as critical signal components that maintain the physiological functions of various cells, particularly the immune cells.
Santosh R. Alluri   +2 more
doaj   +3 more sources

Chemokines and chemokine receptors: A new strategy for breast cancer therapy

open access: yesCancer Medicine, 2020
Chemokines and chemokine receptors not only participate in the development of tissue differentiation, hematopoiesis, inflammation, and immune regulation but also play an important role in the process of tumor development.
Hui Liu   +8 more
doaj   +2 more sources

Chemokines and chemokine receptors in Behçet's disease. [PDF]

open access: yesFront Immunol, 2023
Behçet’s disease (BD), a chronic vascular inflammatory disease, is characterized by the symptoms of ocular lesions, recurrent genital and oral ulcers, skin symptoms and arthritis in addition to neurological, intestinal and vascular involvement. The pathogenesis of BD is poorly understood, and there are no effective laboratory markers for the diagnosis ...
Li Z, Cheng L, Zhan H, Li Y.
europepmc   +4 more sources

Viral Chemokine Receptors [PDF]

open access: yesFrontiers in Immunology, 2015
When my lab sequenced the first chemokine receptors CXCR2 and CCR1 in 1991, the top BLAST hit for CCR1 was open reading frame (ORF) US28 of human cytomegalovirus (HCMV), indicating an obvious common ancestor and a possible example of gene piracy. Pox virologists had already identified virally encoded TNF and IFN-γ binding proteins, copied from the host
Philip eMurphy
doaj   +3 more sources

Role of Atypical Chemokine Receptors in Microglial Activation and Polarization

open access: yesFrontiers in Aging Neuroscience, 2017
Inflammatory reactions occurring in the central nervous system (CNS), known as neuroinflammation, are key components of the pathogenic mechanisms underlying several neurological diseases.
Valentina Salvi   +6 more
doaj   +3 more sources

Chemokines and chemokine receptors in CNS pathology [PDF]

open access: yesJournal of NeuroVirology, 1999
Chemokines are small proinflammatory cytokineswhich stimulate migration of inflammatory cells invitro and in vivo. They can be divided according tostructure, function and gene localization into fourdifferent subfamilies. Chemokines have been as-cribed diverse additional functions, including reg-ulation of angiogenesis, control of cell proliferationand ...
Richard Ransohoff, A R Glabinski
exaly   +3 more sources

CC chemokine receptors are prognostic indicators of gastric cancer and are associated with immune infiltration [PDF]

open access: yesBMC Medical Genomics
Background CC chemokine receptors are responsible for regulating the tumor microenvironment (TME) and participating in carcinogenesis and tumor advancement.
Xinghe Liao   +4 more
doaj   +2 more sources

Differential expression of chemokine receptors on monocytes in TB and HIV S [PDF]

open access: yesHeliyon, 2023
In the present study, we defined multiple chemokine receptors expressed by classical, intermediate and non-classical monocyte subsets in TB, HIV and TB/HIV co-infection and associate it with the perturbation of monocyte subsets due to the diseases ...
Wegene Tamene   +7 more
doaj   +2 more sources

Chemokines and Chemokine Receptors in Multiple Sclerosis [PDF]

open access: yesMediators of Inflammation, 2014
Multiple sclerosis is an autoimmune disease with classical traits of demyelination, axonal damage, and neurodegeneration. The migration of autoimmune T cells and macrophages from blood to central nervous system as well as the destruction of blood brain ...
Wenjing Cheng, Guangjie Chen
doaj   +3 more sources

The Role of Atypical Chemokine Receptors in Neuroinflammation and Neurodegenerative Disorders [PDF]

open access: yesInternational Journal of Molecular Sciences, 2023
Josué Gonzalez Murcia   +2 more
exaly   +2 more sources

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