Results 21 to 30 of about 174,841 (260)
New insights in chemokine signaling [version 1; referees: 3 approved]
F1000Research, 2018 Chemokine signaling is essential for coordinated cell migration in health and disease to specifically govern cell positioning in space and time. Typically, chemokines signal through heptahelical, G protein-coupled receptors to orchestrate cell migration.
Daniel F. Legler, Marcus Thelen
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Seric chemokines and chemokine receptors in eosinophils during acute human schistosomiasis mansoni
Memorias do Instituto Oswaldo Cruz, 2010 The recruitment of circulating eosinophils by chemokines and chemokine receptors plays an important role in the inflammation process in acute human schistosomiasis.
Denise Silveira-Lemos +10 more
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Role of Atypical Chemokine Receptors in Microglial Activation and Polarization
Frontiers in Aging Neuroscience, 2017 Inflammatory reactions occurring in the central nervous system (CNS), known as neuroinflammation, are key components of the pathogenic mechanisms underlying several neurological diseases.
Valentina Salvi +6 more
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Multiple Roles for Chemokines in Neutrophil Biology
Frontiers in Immunology, 2020 Chemokines are recognized as the most critical mediators for selective neutrophil recruitment during inflammatory conditions. Furthermore, they are considered fundamental regulators of neutrophil mobilization from the bone marrow (BM) to the bloodstream ...
Arianna Capucetti +4 more
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Targeting Chemokines and Chemokine GPCRs to Enhance Strong Opioid Efficacy in Neuropathic Pain
Life, 2022 Neuropathic pain (NP) originates from an injury or disease of the somatosensory nervous system. This heterogeneous origin and the possible association with other pathologies make the management of NP a real challenge.
Martina Vincenzi +5 more
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Dermatologica Sinica, 2012 Skin is an immunological organ with a delicate immunological network that governs the homeostasis and homing of the pro- and anti-inflammatory immune cells.
Chih-Hung Lee, Sam Tzen-Yue Hwang
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Prospects for targeting ACKR1 in cancer and other diseases
Frontiers in Immunology, 2023 The chemokine network is comprised of a family of signal proteins that encode messages for cells displaying chemokine G-protein coupled receptors (GPCRs).
Kyler S. Crawford, Brian F. Volkman
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Evolution of chemokine receptors is driven by mutations in the sodium binding site.
PLoS Computational Biology, 2018 Chemokines and their receptors (members of the GPCR super-family) are involved in a wide variety of physiological processes and diseases; thus, understanding the specificity of the chemokine receptor family could help develop new receptor specific drugs.
Bruck Taddese +7 more
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The role of CXCR3 and its ligands in cancer
Frontiers in Oncology, 2022 Chemokines are a class of small cytokines or signaling proteins that are secreted by cells. Owing to their ability to induce directional chemotaxis of nearby responding cells, they are called chemotactic cytokines. Chemokines and chemokine receptors have
Xiaoming Wang +7 more
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The bovine chemokine receptors and their mRNA abundance in mononuclear phagocytes
BMC Genomics, 2010 Background The chemokine and chemokine receptor families play critical roles in both the healthy and diseased organism mediating the migration of cells.
Ashley George +7 more
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