Results 41 to 50 of about 763,282 (296)

The bovine chemokine receptors and their mRNA abundance in mononuclear phagocytes

BMC Genomics, 2010
Background The chemokine and chemokine receptor families play critical roles in both the healthy and diseased organism mediating the migration of cells.
Ashley George, Lawrence Freya, Easton Victoria, Siddiqui Nazneen, Widdison Stephanie, Werling Dirk, Watson Michael, Coffey Tracey J   +7 more
doaj   +1 more source

The role of CXCR3 and its ligands in cancer

Frontiers in Oncology, 2022
Chemokines are a class of small cytokines or signaling proteins that are secreted by cells. Owing to their ability to induce directional chemotaxis of nearby responding cells, they are called chemotactic cytokines. Chemokines and chemokine receptors have
Xiaoming Wang, Yangyang Zhang, Sen Wang, Hongyan Ni, Peng Zhao, Guangyu Chen, Benling Xu, Long Yuan   +7 more
doaj   +1 more source

Molecular insights into kinase mediated signaling pathways of chemokines and their cognate G protein coupled receptors

Frontiers in Bioscience-Landmark, 2020
Chemokines are small regulatory proteins that play a crucial role in the coordinated migration of cell populations to the site of infection/inflammation by binding to their cognate receptors.
Deepak Kumar Tripathi, Krishna Mohan Poluri   +1 more
doaj   +1 more source

Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]

, 2004
Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Anders, Hans-Joachim, Vielhauer, Volker, Eis, Vaclav, Schlöndorff, Detlef   +3 more
core   +1 more source

Spatio-temporal regulation of concurrent developmental processes by generic signaling downstream of chemokine receptors

eLife, 2018
Chemokines are secreted proteins that regulate a range of processes in eukaryotic organisms. Interestingly, different chemokine receptors control distinct biological processes, and the same receptor can direct different cellular responses, but the basis ...
Divyanshu Malhotra, Jimann Shin, Lilianna Solnica-Krezel, Erez Raz   +3 more
doaj   +1 more source

Chemokines, molecular drivers of thromboinflammation and immunothrombosis

Frontiers in Immunology, 2023
Blood clotting is a finely regulated process that is essential for hemostasis. However, when dysregulated or spontaneous, it promotes thrombotic disorders.
Julian Leberzammer, Julian Leberzammer, Julian Leberzammer, Philipp von Hundelshausen, Philipp von Hundelshausen   +4 more
doaj   +1 more source

Chemokines, chemokine receptors, and cancer metastasis [PDF]

Journal of Leukocyte Biology, 2006
Abstract It is clear from large clinical studies that selected chemokine receptors are often up-regulated in a large number of common human cancers, including those of the breast, lung, prostate, colon, and melanoma. Chemokine receptors and their corresponding chemokine ligands have been demonstrated to play a number of nonredundant ...
Takashi, Kakinuma, Sam T, Hwang
openaire   +2 more sources

CC Chemokine Receptors in Lung Adenocarcinoma: The Inflammation-Related Prognostic Biomarkers and Immunotherapeutic Targets

Journal of Inflammation Research, 2021
Fangteng Liu,1,2 Hengyu Wu1 1Department of Breast Surgery, The Third Hospital of Nanchang, Nanchang, Jiangxi, 330009, People’s Republic of China; 2Faculty of Medicine, University of Munich, Munich, 80336, GermanyCorrespondence: Hengyu Wu Tel +86 ...
Liu F, Wu H
doaj  

Chemokines, Chemokine Receptors and Atherosclerosis

, 2005
Publisher Summary This chapter focuses on chemokines, chemokine receptors, and atherosclerosis. Chemokines play essential roles in inflammation and disease. This family of inflammatory mediators has diverse roles in both immune and inflammatory responses, including the regulation of cellular recruitment, activation, and differentiation.
John, A, Channon, K, Greaves, D
openaire   +2 more sources

CXCR7 functions as a scavenger for CXCL12 and CXCL11. [PDF]

, 2010
CXCR7 (RDC1), the recently discovered second receptor for CXCL12, is phylogenetically closely related to chemokine receptors, but fails to couple to G-proteins and to induce typical chemokine receptor mediated cellular responses. The function of CXCR7 is
Pruenster, M, Mahabaleshwar, Harsha, Ulrike Naumann, Raz Erez, Rot, Antal, Rot Antal, Marcus Thelen, Naumann, U, Zerwes Hans-Günter, Harsha Mahabaleshwar, Naumann Ulrike, Cameroni, E, Mahabaleshwar, H, Elisabetta Cameroni, Zerwes, Hans-Günter, Raz, E, Pruenster Monika, Mahabaleshwar Harsha, Monika Pruenster, Hans-Günter Zerwes, Pruenster, Monika, Thelen, M, Thelen Marcus, Naumann, Ulrike, Cameroni, Elisabetta, Cameroni Elisabetta, Raz, Erez, Zerwes, HG, Antal Rot, Erez Raz, Thelen, Marcus   +30 more
core   +1 more source