Results 41 to 50 of about 275,450 (304)
Dermatologica Sinica, 2012 Skin is an immunological organ with a delicate immunological network that governs the homeostasis and homing of the pro- and anti-inflammatory immune cells.
Chih-Hung Lee, Sam Tzen-Yue Hwang
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The role of CXCR3 and its ligands in cancer
Frontiers in Oncology, 2022 Chemokines are a class of small cytokines or signaling proteins that are secreted by cells. Owing to their ability to induce directional chemotaxis of nearby responding cells, they are called chemotactic cytokines. Chemokines and chemokine receptors have
Xiaoming Wang +7 more
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Mathematical Model of HIV superinfection dynamics and R5 to X4 switch [PDF]
, 2006 During the HIV infection several quasispecies of the virus arise, which are able to use different coreceptors, in particular the CCR5 and CXCR4 coreceptors (R5 and X4 phenotypes, respectively).
Bagnoli, Franco +2 more
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Evolution of chemokine receptors is driven by mutations in the sodium binding site.
PLoS Computational Biology, 2018 Chemokines and their receptors (members of the GPCR super-family) are involved in a wide variety of physiological processes and diseases; thus, understanding the specificity of the chemokine receptor family could help develop new receptor specific drugs.
Bruck Taddese +7 more
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Chemokines and chemokine receptors: an overview
Frontiers in Bioscience, 2009 Chemokines are chemotactic cytokines orchestrating leukocyte recruitment in physiological and pathological conditions. This complex system includes 42 molecules and 19 receptors and is subjected to different levels of regulation, including ligand production, post-translational modifications and degradation, as well as receptor expression and signaling ...
R. Bonecchi +5 more
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The bovine chemokine receptors and their mRNA abundance in mononuclear phagocytes
BMC Genomics, 2010 Background The chemokine and chemokine receptor families play critical roles in both the healthy and diseased organism mediating the migration of cells.
Ashley George +7 more
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Atypical chemokine receptor ACKR2 controls branching morphogenesis in the developing mammary gland [PDF]
, 2016 Macrophages are important regulators of branching morphogenesis during development and postnatally in the mammary gland. Regulation of macrophage dynamics during these processes can therefore have a profound impact on development.
Cairney, Claire J. +7 more
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Frontiers in Bioscience-Landmark, 2020 Chemokines are small regulatory proteins that play a crucial role in the coordinated migration of cell populations to the site of infection/inflammation by binding to their cognate receptors.
Deepak Kumar Tripathi +1 more
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Chemokines, molecular drivers of thromboinflammation and immunothrombosis
Frontiers in Immunology, 2023 Blood clotting is a finely regulated process that is essential for hemostasis. However, when dysregulated or spontaneous, it promotes thrombotic disorders.
Julian Leberzammer +4 more
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What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands [PDF]
, 2019 Dipeptidyl peptidase 4 (DPP4) is an exopeptidase found either on cell surfaces where it is highly regulated in terms of its expression and surface availability (CD26) or in a free/circulating soluble constitutively available and intrinsically active form.
Aguilar-Pérez, Alexandra +13 more
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