Results 31 to 40 of about 763,282 (296)

The role of the chemokine receptor CXCR4 in infection with feline immunodeficiency virus [PDF]

, 1999
Infection with feline immunodeficiency virus (FIV) leads to the development of a disease state similar to AIDS in man. Recent studies have identified the chemokine receptor CXCR4 as the major receptor for cell culture-adapted strains of FIV, suggesting ...
Hosie, M.J., Willett, B.J., Margaret J. Hosie, Brian J. Willett,   +3 more
core   +1 more source

Seric chemokines and chemokine receptors in eosinophils during acute human schistosomiasis mansoni

Memorias do Instituto Oswaldo Cruz, 2010
The recruitment of circulating eosinophils by chemokines and chemokine receptors plays an important role in the inflammation process in acute human schistosomiasis.
Denise Silveira-Lemos, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Adriano Luiz Souza-Soares, Pollyanna Castro-Silva, Matheus Fernandes Costa-Silva, Pedro Henrique Gazzinelli Guimarães, Helena Barbosa Ferraz, Lúcia Alves Oliveira-Fraga, Mauro Martins Teixeira, Rodrigo Corrêa-Oliveira   +10 more
doaj   +1 more source

Multiple Roles for Chemokines in Neutrophil Biology

Frontiers in Immunology, 2020
Chemokines are recognized as the most critical mediators for selective neutrophil recruitment during inflammatory conditions. Furthermore, they are considered fundamental regulators of neutrophil mobilization from the bone marrow (BM) to the bloodstream ...
Arianna Capucetti, Francesca Albano, Francesca Albano, Raffaella Bonecchi, Raffaella Bonecchi   +4 more
doaj   +1 more source

Phenotyping renal leukocyte subsets by four-color flow cytometry: Characterization of chemokine receptor expression [PDF]

, 2003
To investigate mechanisms of cell-mediated injury in renal inflammatory disease it is critical to determine the surface phenotype of infiltrating renal leukocyte subsets.
Anders, Hans-Joachim, de Lema, Guillermo Pérez, Mack, Matthias, Vielhauer, Volker, Schlöndorff, Detlef, Luckow, Bruno   +5 more
core   +1 more source

Pathophysiology of chemokines and chemokine receptors in dermatological science: A focus on psoriasis and cutaneous T-cell lymphoma

Dermatologica Sinica, 2012
Skin is an immunological organ with a delicate immunological network that governs the homeostasis and homing of the pro- and anti-inflammatory immune cells.
Chih-Hung Lee, Sam Tzen-Yue Hwang
doaj   +1 more source

Prospects for targeting ACKR1 in cancer and other diseases

Frontiers in Immunology, 2023
The chemokine network is comprised of a family of signal proteins that encode messages for cells displaying chemokine G-protein coupled receptors (GPCRs).
Kyler S. Crawford, Brian F. Volkman
doaj   +1 more source

Evolution of chemokine receptors is driven by mutations in the sodium binding site.

PLoS Computational Biology, 2018
Chemokines and their receptors (members of the GPCR super-family) are involved in a wide variety of physiological processes and diseases; thus, understanding the specificity of the chemokine receptor family could help develop new receptor specific drugs.
Bruck Taddese, Madeline Deniaud, Antoine Garnier, Asma Tiss, Hajer Guissouma, Hervé Abdi, Daniel Henrion, Marie Chabbert   +7 more
doaj   +1 more source

Targeting Chemokines and Chemokine GPCRs to Enhance Strong Opioid Efficacy in Neuropathic Pain

Life, 2022
Neuropathic pain (NP) originates from an injury or disease of the somatosensory nervous system. This heterogeneous origin and the possible association with other pathologies make the management of NP a real challenge.
Martina Vincenzi, Michele Stanislaw Milella, Ginevra D’Ottavio, Daniele Caprioli, Ingrid Reverte, Daniela Maftei   +5 more
doaj   +1 more source

Prediction of Structure, Function, and Spectroscopic Properties of G-Protein-Coupled Receptors: Methods and Applications [PDF]

, 2004
G-protein-coupled receptors are of great pharmaceutical interest, comprising the majority of targets for currently marketed drugs. The theme of my thesis is the development of the structure prediction method, MembStruk, for the superfamily of G-protein ...
Trabanino, Rene Jouvanni
core   +1 more source

Chemokine receptors in GtoPdb v.2023.1 [PDF]

, 2023
Chemokine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Chemokine Receptors [438, 437, 32]) comprise a large subfamily of 7TM proteins that bind one or more chemokines, a large family of small cytokines typically possessing ...
Nomiyama, Hisayuki, Kouji Matsushima, Robert J. B. Nibbs, Proudfoot , Amanda E. I., Rot, Antal, Israel F. Charo, Christophe Combadiere, Mette M. Rosenkilde, Murphy, Philip M., Graham, Gerard J., Amanda M. Burkhardt, Francoise Bachelerie, Hills, Rebecca, Adit Ben-Baruch, Joshua M. Farber, Christine A. Power, Nibbs, Robert J. B., Uddin, Mohib, Rebecca Hills, Monaghan, Amy E., Farber, Joshua M., Mantovani, Alberto, Alberto Mantovani, Silvano Sozzani, Alexander H. Sparre-Ulrich, Charo, Israel F., Antal Rot, Andrew D. Luster, Thelen, Marcus, Georgios L. Moschovakis, Yoshie, Osamu, Luster, Andrew D., Power, Christine A., Joost J. Oppenheim, Osamu Yoshie, Oppenheim, Joost J., Amanda E. I. Proudfoot , Marcus Thelen, Ben-Baruch, Adit, Locati, Massimo, Matsushima, Kouji, Albert Zlotnik, Burkhardt, Amanda M., Rosenkilde, Mette M., Sparre-Ulrich, Alexander H., Combadiere, Christophe, Bachelerie, Francoise, Reinhold Förster, Sozzani, Silvano, Gerard J. Graham, Förster, Reinhold, Moschovakis, Georgios L., Amy E. Monaghan, Massimo Locati, Philip M. Murphy, Hisayuki Nomiyama, Zlotnik, Albert, Richard Horuk, Mohib Uddin, Horuk, Richard   +59 more
core   +1 more source