Results 91 to 100 of about 37,862 (221)

Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles

Nature Communications, 2019
Oncogenic exosomes can circulate in the blood, but their selective removal has not been possible. Here the authors show that aptamer-functionalised mesoporous silica nanoparticles can find to a specific population of circulating exosomes and eliminate ...
Xiaodong Xie, Huifang Nie, Yu Zhou, Shu Lian, Hao Mei, Yusheng Lu, Haiyan Dong, Fengqiao Li, Tao Li, Bifei Li, Jie Wang, Min Lin, Chaihung Wang, Jingwei Shao, Yu Gao, Jianming Chen, Fangwei Xie, Lee Jia   +17 more
doaj   +1 more source

Cancer Chemoprevention Using Nanotechnology-Based Approaches

Frontiers in Pharmacology, 2020
Cancer research in pursuit of better diagnostic and treatment modalities has seen great advances in recent years. However, the incidence rate of cancer is still very high. Almost 40% of women and men are diagnosed with cancer during their lifetime.
Preshita Desai, Naga Jyothi Thumma, Pushkaraj Rajendra Wagh, Shuyu Zhan, Shuyu Zhan, David Ann, Jeffrey Wang, Sunil Prabhu   +7 more
doaj   +1 more source

Honokiol regulates Acute respiratory distress syndrome (ARDS)‐associated pulmonary fibrosis via the miR‐19a‐3p/POSTN axis

British Journal of Pharmacology, Volume 183, Issue 21, Page 6329-6351, November 2026.
Abstract Background and Purpose Acute respiratory distress syndrome (ARDS) and subsequent pulmonary fibrosis are associated with high mortality and limited treatment options. Periostin (POSTN) is a profibrotic mediator predicted to be regulated by microRNA‐19a‐3p (miR‐19a‐3p), but the relevance of this axis in ARDS‐associated pulmonary fibrosis remains
Weilun Liu, Hsiaohsuan Wang, Hsuanfu Kuo, Chiahung Yen, Modasang Hua, Chiayuan Chang, Zhiwei Xu, Ifan Liu, Chongchao Hsieh, Chihhsin Hsu, Chiayang Li, Shuchi Wang, Yunghsiang Chen, Menghsuan Cheng, Polen Liu   +14 more
wiley   +1 more source

AndriaMousa/chemoprevention-trial-code

Code used to simulate and analyse chemoprevention trial scenarios, related to study design, and participant and setting characteristics for "Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention ...
Mousa, Andria
core   +2 more sources

IMPROVMENT OF TUBERCULOSIS CHEMOPREVENTION IN HIV-INFECTED PATIENTS

Медицинский вестник Юга России, 2016
Objective: substantiation  for the use of various schemes for chemoprevention  of tuberculosis in HIV-infected patients.Materials and methods: for the study used data from the Cabinet of the early detection of tuberculosis outpatient card (form №025 ...
M. V. Sinitsyn, L. B. Ayusheva, L. V. Kolpakova   +2 more
doaj   +1 more source

Cell-Free DNA Plasma Levels Differ in Age-Specific Pattern in Healthy Rats and Castrates with Testosterone-Induced Benign Prostatic Hyperplasia

International Journal of Genomics, 2019
The purpose of this work was to study changes in the level of cell-free DNA (cfDNA) in the blood of young and old rats in the normal state and with induced benign prostatic hyperplasia (BPH).
I. N. Vasilyeva, V. G. Bespalov, J. D. Von, A. L. Semenov, G. V. Tochilnikov, V. A. Romanov, I. K. Alvovsky, D. A. Baranenko   +7 more
doaj   +1 more source

Pilot study of decision support tools on breast cancer chemoprevention for high-risk women and healthcare providers in the primary care setting

BMC Medical Informatics and Decision Making, 2018
Background Breast cancer chemoprevention can reduce breast cancer incidence in high-risk women; however, chemoprevention is underutilized in the primary care setting.
Rita Kukafka, Jiaqi Fang, Alejandro Vanegas, Thomas Silverman, Katherine D. Crew   +4 more
doaj   +1 more source

Co-delivery of sorafenib and metapristone encapsulated by CXCR4-targeted PLGA-PEG nanoparticles overcomes hepatocellular carcinoma resistance to sorafenib

Journal of Experimental & Clinical Cancer Research, 2019
Background Sorafenib is approved as a standard therapy for advanced hepatocellular carcinoma (HCC), but its clinical application is limited due to moderate therapeutic efficacy and high incidence of acquired resistance resulted from elevated levels of ...
Ning Zheng, Weiqun Liu, Bifei Li, Huifang Nie, Jian Liu, Yunlong Cheng, Jichuang Wang, Haiyan Dong, Lee Jia   +8 more
doaj   +1 more source

The Selectivity of Ethanolic Extract of Buah Makassar (Brucea javanica) on Metastatic Breast Cancer Cells

Journal of Agromedicine and Medical Sciences (AMS), 2016
Treatment of cancer such as surgery, radiotherapy and chemotherapy has many side effects. Chemopreventive agent is needed to reduce the side effect and increase the effectivity of therapy.
Ika Rahmawati Sutejo, Herwandhani Putri, Edy Meiyanto   +2 more
doaj  

Chemoprevention of Colorectal Cancer

, 2000
Goal After completing this CE program, the participant will understand the basic concepts of chemoprevention and will be able to discuss the currently existing clinical data for the chemoprevention of colorectal cancer.
Theresa Mays-Holland
core   +1 more source