Results 91 to 100 of about 61,449 (214)

The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice [PDF]

open access: yes, 2007
Dissemination of metastatic cells probably occurs long before diagnosis of the primary tumor. Metastasis during early phases of carcinogenesis in high risk patients is therefore a potential prevention target.
Adriana Albini   +70 more
core   +1 more source

Cancer history and cancer risk communication among Arab–American families: Perspectives of young Arab–Americans in Michigan

open access: yesJournal of Genetic Counseling, Volume 35, Issue 2, April 2026.
Abstract The Arab population in the United States is among the most understudied ethnic populations in access to cancer genetics services. Similar to other underserved populations, Arab–Americans face several institutional, social, and cultural barriers that inhibit access to and uptake of cancer genetic counseling and germline genetic testing.
Hiam M. Abdel‐Salam   +5 more
wiley   +1 more source

Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles

open access: yesNature Communications, 2019
Oncogenic exosomes can circulate in the blood, but their selective removal has not been possible. Here the authors show that aptamer-functionalised mesoporous silica nanoparticles can find to a specific population of circulating exosomes and eliminate ...
Xiaodong Xie   +17 more
doaj   +1 more source

Expression of μ-protocadherin is negatively regulated by the activation of the β-catenin signaling pathway in normal and cancer colorectal enterocytes. [PDF]

open access: yes, 2016
Mu-protocadherin (MUCDHL) is an adhesion molecule predominantly expressed by colorectal epithelial cells which is markedly downregulated upon malignant transformation.
Calabretta, Bruno   +11 more
core   +2 more sources

Pilot study of decision support tools on breast cancer chemoprevention for high-risk women and healthcare providers in the primary care setting

open access: yesBMC Medical Informatics and Decision Making, 2018
Background Breast cancer chemoprevention can reduce breast cancer incidence in high-risk women; however, chemoprevention is underutilized in the primary care setting.
Rita Kukafka   +4 more
doaj   +1 more source

Violacein, an indole-derived purple-colored natural pigment produced by Janthinobacterium lividum, inhibits the growth of head and neck carcinoma cell lines both in vitro and in vivo [PDF]

open access: yes, 2015
Violacein (VIO; 3-[1,2-dihydro-5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-ylidene]-1,3-dihydro-2H-indol-2-one), an indole-derived purple-colored pigment, produced by a limited number of Gram-negative bacteria species, including Chromobacterium ...
Bei, Roberto   +12 more
core   +1 more source

Cell-Free DNA Plasma Levels Differ in Age-Specific Pattern in Healthy Rats and Castrates with Testosterone-Induced Benign Prostatic Hyperplasia

open access: yesInternational Journal of Genomics, 2019
The purpose of this work was to study changes in the level of cell-free DNA (cfDNA) in the blood of young and old rats in the normal state and with induced benign prostatic hyperplasia (BPH).
I. N. Vasilyeva   +7 more
doaj   +1 more source

Effect of DNA repair deficiencies on the cytotoxicity of resveratrol [PDF]

open access: yes, 2015
Numerous preclinical studies have shown that the naturally-occurring polyphenol resveratrol may produce health-beneficial effects in a variety of disorders, including cancer, diabetes, Alzheimer, and cardiovascular diseases.
Burgos Morón, Estefanía   +5 more
core  

Making the most of malaria chemoprevention

open access: yesMalaria Journal
Against a backdrop of stalled progress in malaria control, it is surprising that the various forms of malaria chemoprevention are not more widely used. The World Health Organization (WHO) has recommended several malaria chemoprevention strategies, some ...
Jasper Littmann   +4 more
doaj   +1 more source

Co-delivery of sorafenib and metapristone encapsulated by CXCR4-targeted PLGA-PEG nanoparticles overcomes hepatocellular carcinoma resistance to sorafenib

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background Sorafenib is approved as a standard therapy for advanced hepatocellular carcinoma (HCC), but its clinical application is limited due to moderate therapeutic efficacy and high incidence of acquired resistance resulted from elevated levels of ...
Ning Zheng   +8 more
doaj   +1 more source

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