Results 1 to 10 of about 74,225 (263)
Synergistic anticancer mechanisms of curcumol and paclitaxel in triple-negative breast cancer treatment may involve down-regulating ZBTB7A expression via the NF-B signaling pathway [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): This study aimed to verify whether curcumol combined with paclitaxel exerted synergistic antiproliferative and proapoptotic effects in MDA-MB-231 mammary cancer cells.Materials and Methods: The effects of different concentrations of CC, PTX,
Anyun Mao +3 more
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Advances in Treatment of Triple Negative Breast Cancer
Zhongliu Fangzhi Yanjiu, 2022 TNBC is a special type of breast cancer with strong aggressiveness and poor prognosis. Chemotherapy is still the main treatment for TNBC, due to poor efficacy of endocrine therapy and targeted therapy. However, TNBC is a kind of heterogeneous disease, so
KANG Yikun, YUAN Peng
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Filamin-A expression in triple-negative breast cancer and its clinical significance
Biotechnology & Biotechnological Equipment, 2021 The quest for discovering novel biomarkers of triple-negative breast cancers (TNBCs) is ongoing. By lacking expression of hormonal receptors, this aggressive subtype of breast cancer presents a clinical dilemma with early recurrence, metastases and poor ...
Abderrahman Ouban
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Reprogramming of VEGF-mediated extracellular matrix changes through autocrine signaling
Cancer Biology & Therapy, 2023 Vascular endothelial growth factor (VEGF) plays key roles in angiogenesis, vasculogenesis, and wound healing. In cancers, including triple negative breast cancer (TNBC), VEGF has been associated with increased invasion and metastasis, processes that ...
Eibhlin Goggins +6 more
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Establishing the promising role of novel combination of triple therapeutics delivery using polymeric nanoparticles for Triple negative breast cancer therapy [PDF]
BioImpacts, 2021 Introduction: Triple-negative breast cancer (TNBC) is a lethal tumor with an advanced degree of metastasis and poor survivability as compared to other subtypes of breast cancer.
Ranjita Misra +3 more
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Disulfiram/Copper Induce Ferroptosis in Triple-Negative Breast Cancer Cell Line MDA-MB-231
Frontiers in Bioscience-Landmark, 2023 Background: The complex formed by disulfiram (DSF) and copper (Cu) is safe and effective for the prevention and treatment of triple-negative breast cancer (TNBC). Although previous studies have shown that DSF/Cu induces ferroptosis, the mechanism remains
Meiran Chu +8 more
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BBOX1 promotes triple-negative breast cancer progression by controlling IP3R3 stability
Molecular & Cellular Oncology, 2020 Limited therapeutic options impede the clinical outcome of triple-negative breast cancer (TNBC). Our recent study uncovered a novel signaling pathway implicating gamma-butyrobetaine hydroxylase 1 (BBOX1) in the control of cell growth in TNBC, via ...
Chengheng Liao, Qing Zhang
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Rarest of the rare-male triple negative breast cancer
Journal of Dr. NTR University of Health Sciences, 2022 Breast cancer in males is rare. Luminal A is the predominant subtype in male breast cancer. Clinical data on triple negative breast cancer in male patients is sparse. This case report will add to the literature on male breast cancers. This is a rare case
Haneesha Polavarapu +4 more
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Archives of Pharmaceutical Sciences Ain Shams University, 2021 Transcription factors (TFs) as SRY-Box transcription factor 11 (SOX11) and B-cell lymphoma/leukemia 11A (BCL11A) role in breast cancer (BC) as well as their effect on epithelial cadherin (E-cadherin) membrane protein which is a metastasis suppressor is a
Salma Salama +3 more
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OncoImmunology, 2020 Triple-negative breast cancer is the most aggressive subtype of breast cancer and is difficult to treat. Breast cancer is considered to be poorly immunogenic and hence is less responsive to immunotherapies.
Shyambabu Chaurasiya +10 more
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