Results 11 to 20 of about 81,406 (283)

Retrospective Analysis of Transcriptomic Differences between Triple-Negative Breast Cancer (TNBC) and non-TNBC

European Journal of Biology
Objective: Triple-negative breast cancer (TNBC), which has no expression of estrogen receptor, progesterone receptor and HER2, is an aggressive subgroup.
Çağlar Berkel
doaj   +3 more sources

The Evaluation of Cytotoxic Properties from CCB-2 Sugar Complexes Against TNBC and Non-TNBC Cells [PDF]

Asian Pacific Journal of Cancer Prevention, 2021
The progress from Boron Neutron Capture Therapy (BNCT) development urged us to explore new targeted and selective boron carriers. Firstly, we reported the successful synthesis of CCB-2 which exerts a cytotoxic effect against triple negative breast cancer (TNBC) cells.
Jenie, Riris Istighfari, Utomo, Rohmad Yudi, Susidarti, Ratna Asmah, Novitasari, Dhania, Kirihata, Mitsunori, Meiyanto, Edy   +5 more
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Neural Functions Play Different Roles in Triple Negative Breast Cancer (TNBC) and non-TNBC [PDF]

Scientific Reports, 2020
AbstractTriple negative breast cancer (TNBC) represents the most malignant subtype of breast cancer, and yet our understanding about its unique biology remains elusive. We have conducted a comparative computational analysis of transcriptomic data of TNBC and non-TNBC (NTNBC) tissue samples from the TCGA database, focused on genes involved in neural ...
Renbo Tan, Haoyang Li, Zhenyu Huang, Yi Zhou, Mingxin Tao, Xin Gao, Ying Xu   +6 more
openaire   +3 more sources

Clinical Significance of the Transcription Factor SOX11, Cell-Cell Adhesion Protein E-cadherin and Zinc Finger Protein BCL11A in the Diagnosis of Breast Cancer

Archives of Pharmaceutical Sciences Ain Shams University, 2021
Transcription factors (TFs) as SRY-Box transcription factor 11 (SOX11) and B-cell lymphoma/leukemia 11A (BCL11A) role in breast cancer (BC) as well as their effect on epithelial cadherin (E-cadherin) membrane protein which is a metastasis suppressor is a
Salma Salama, Nadia Hamdy, Reham El-Shimy, Hala El-Mesallamy   +3 more
doaj   +1 more source

NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest. [PDF]

, 2018
Notch dysregulation has been implicated in numerous tumors, including triple-negative breast cancer (TNBC), which is the breast cancer subtype with the worst clinical outcome.
Bellavia, Diana, Besharat, ZEIN MERSINI, Capalbo, Carlo, Checquolo, Saula, D'Amati, Giulia, Del Gaudio, Francesca, Diluvio, Giulia, Franciosa, Giulia, Giuli, MARIA VALERIA, Giuliani, Eugenia, Maroder, Marella, Palermo, Rocco, Pignataro, MARIA GEMMA, Talora, Claudio, Vacca, Alessandra   +14 more
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Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. [PDF]

, 2016
Expression of the oncogenic transcription factor MYC is disproportionately elevated in triple-negative breast cancer (TNBC), as compared to estrogen receptor-, progesterone receptor- or human epidermal growth factor 2 receptor-positive (RP) breast cancer.
Anderton, Brittany, Balakrishnan, Sanjeev, Camarda, Roman, Eyob, Henok, Goga, Andrei, Kajimura, Shingo, Kohnz, Rebecca A, Krings, Gregor, Mahieu, Celine, Nomura, Daniel K, Tward, Aaron, Zhou, Alicia Y   +11 more
core   +1 more source

Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures [PDF]

, 2011
Background: Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers.
Karn, Thomas, Pusztai, Lajos, Holtrich, Uwe, Iwamoto, Takayuki, Shiang, Christine Y., Schmidt, Marcus, Müller, Volkmar, Solbach, Christine, Gätje, Regine, Hanker, Lars, Ahr, André, Liedtke, Cornelia, Ruckhäberle, Eugen, Kaufmann, Manfred, Rody, Achim   +14 more
core   +1 more source

Oncolytic poxvirus CF33-hNIS-ΔF14.5 favorably modulates tumor immune microenvironment and works synergistically with anti-PD-L1 antibody in a triple-negative breast cancer model

OncoImmunology, 2020
Triple-negative breast cancer is the most aggressive subtype of breast cancer and is difficult to treat. Breast cancer is considered to be poorly immunogenic and hence is less responsive to immunotherapies.
Shyambabu Chaurasiya, Annie Yang, Seonah Kang, Jianming Lu, Sang-In Kim, Anthony K. Park, Venkatesh Sivanandam, Zhifang Zhang, Yanghee Woo, Susanne G. Warner, Yuman Fong   +10 more
doaj   +1 more source

Regulation of p53 and survivin by Curcuma longa extract to caspase-3 dependent apoptosis in triple negative breast cancer cells [PDF]

Medicinski Glasnik, 2022
Aim Triple negative breast cancer cells (TNBC) are the population of breast cancer cells that are responsible for cancer recurrence and apoptosis resistance.
Deryne Anggia Paramita, Dedy Hermansyah, Desiree Anggia Paramita, Nur Dina Amalina   +3 more
doaj   +1 more source

Cripto-1 in TNBC

Aging, 2015
Among all breast cancer molecular subtypes, triple-negative breast cancer (TNBC) presents the poorest prognosis due to the lack of effective therapeutic options. TNBC, characterized by tumors that do not express estrogen receptor (ER), progesterone receptor (PR), or HER-2 genes, represents approximately 10%–20% of invasive breast cancers and has been ...
Nadia P, Castro, David S, Salomon
openaire   +2 more sources