Results 21 to 30 of about 82,941 (302)
SHOC2 mediates the drug-resistance of triple-negative breast cancer cells to everolimus
Cancer Biology & Therapy, 2023 Aberrant activation of the mTOR pathway is a characteristic alteration in triple-negative breast cancer, but the mTOR pathway inhibitor everolimus is not effective for the triple-negative breast cancer (TNBC) patients.
Wenwen Geng +4 more
doaj +1 more source
Regulation of p53 and survivin by Curcuma longa extract to caspase-3 dependent apoptosis in triple negative breast cancer cells [PDF]
Medicinski Glasnik, 2022 Aim Triple negative breast cancer cells (TNBC) are the population of breast cancer cells that are responsible for cancer recurrence and apoptosis resistance.
Deryne Anggia Paramita +3 more
doaj +1 more source
High MYC mRNA expression is more clinically relevant than MYC DNA amplification in triple-negative breast cancer [PDF]
, 2019 DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC).
Dasgupta, Subhamoy +6 more
core +2 more sources
Drug Delivery, 2018 Gambogic acid (GA) is a naturally derived potent anticancer agent with extremely poor biocompatibility. In the present study, a novel of redox/pH dual-responsive multifunctional magnetic complex micelle (sPEG/HA/CSO-SS-Hex/Fe3O4/GA), which consisted of a
Mang Mang Sang +10 more
doaj +1 more source
The Potential of PSMA as a Vascular Target in TNBC
Cells, 2023 Recent studies proving prostate-specific membrane antigen (PSMA) expression on triple-negative breast cancer (TNBC) cells and adjacent endothelial cells suggest PSMA as a promising target for therapy of until now not-targetable cancer entities. In this study, PSMA and its isoform expression were analyzed in different TNBC cells, breast cancer stem ...
Amelie Heesch +6 more
openaire +5 more sources
Neural Functions Play Different Roles in Triple Negative Breast Cancer (TNBC) and non-TNBC [PDF]
Scientific Reports, 2020 AbstractTriple negative breast cancer (TNBC) represents the most malignant subtype of breast cancer, and yet our understanding about its unique biology remains elusive. We have conducted a comparative computational analysis of transcriptomic data of TNBC and non-TNBC (NTNBC) tissue samples from the TCGA database, focused on genes involved in neural ...
Renbo Tan +6 more
openaire +3 more sources
Clinical and Experimental Obstetrics & Gynecology, 2023 Background: The population of older women (≥70 years old) with triple-negative breast cancer (TNBC) is increasing, but there are few prognostic studies for these patients.
Chongwu He +7 more
doaj +1 more source
The addition of bevacizumab to standard chemotherapy in breast cancer : which patient benefits the most? [PDF]
, 2013 Bevacizumab, a humanized monoclonal antibody directed against vascular endothelial growth factor, is an effective and well-tolerated treatment option for patients with breast cancer.
Cocquyt, Veronique +4 more
core +2 more sources
Luminescent iridium(III)-pyridyl based complexes: tumor inhibitory studies in 4T1 mammary carcinoma mice model [PDF]
Exploration of Drug ScienceAim: The iridium(III) [Ir(III)] complexes exhibit anticancer properties, and along with their photoluminescence properties, they can be employed as diagnostic agents. Hence, we have tried to evaluate both properties.
Natesan Sundarmurthy Karthikeyan +5 more
doaj +1 more source
Molecular & Cellular Oncology, 2020 Lipid and cholesterol reprogramming are often observed in specific cancer subtypes. We find that triple-negative breast cancers (TNBCs), but not estrogen receptor-positive (ER+) ones, adopt nuclear receptor RAR-related orphan receptor γ (RORγ) as their ...
Demin Cai, Xiong Zhang, Hong-Wu Chen
doaj +1 more source