Results 31 to 40 of about 81,406 (283)

Luminescent iridium(III)-pyridyl based complexes: tumor inhibitory studies in 4T1 mammary carcinoma mice model [PDF]

Exploration of Drug Science
Aim: The iridium(III) [Ir(III)] complexes exhibit anticancer properties, and along with their photoluminescence properties, they can be employed as diagnostic agents. Hence, we have tried to evaluate both properties.
Natesan Sundarmurthy Karthikeyan, Shishu Kant Suman, Prasad P. Phadnis, Lalrinawma Zote, Chandan Kumar, Vasanthakumaran Sudarsan   +5 more
doaj   +1 more source

Moderate Exercise Modulates Tumor Metabolism of Triple-Negative Breast Cancer

Cells, 2020
Triple-negative breast cancer (TNBC) stands out for its aggressiveness and accelerated rate of proliferation. Evidence shows that exercise may exert antitumorigenic effects, but the biochemical mechanisms underlying them remain unclear. Our objective was
Anderson Vulczak, Anderson de Oliveira Souza, Gustavo Duarte Ferrari, Ana Elisa Caleiro Seixas Azzolini, Gabriela Pereira-da-Silva, Luciane Carla Alberici   +5 more
doaj   +1 more source

Combined Analysis of Disseminated Tumor Cells (DTCs) and Circulating Tumor DNA (ctDNA) in a Patient Suffering from Triple Negative Breast Cancer Revealed Elevated Risk

Frontiers in Bioscience-Landmark, 2022
Background: Disseminated tumor cells (DTCs) in bone marrow aspirates of patients with primary breast cancer may serve as independent prognostic markers associated with impaired survival.
Ivonne Nel, Henrike Herzog, Bahriye Aktas   +2 more
doaj   +1 more source

The addition of bevacizumab to standard chemotherapy in breast cancer : which patient benefits the most? [PDF]

, 2013
Bevacizumab, a humanized monoclonal antibody directed against vascular endothelial growth factor, is an effective and well-tolerated treatment option for patients with breast cancer.
Cocquyt, Veronique, Denys, Hannelore, KRUSE, VIBEKE, Van Belle, Simon, Van den Broecke, Rudy   +4 more
core   +2 more sources

The Molecular Mechanisms behind Advanced Breast Cancer Metabolism: Warburg Effect, OXPHOS, and Calcium

Frontiers in Bioscience-Landmark
Altered metabolism represents a fundamental difference between cancer cells and normal cells. Cancer cells have a unique ability to reprogram their metabolism by deviating their reliance from primarily oxidative phosphorylation (OXPHOS) to glycolysis, in
Erna Mitaishvili, Hanna Feinsod, Zachary David, Jessica Shpigel, Chelsea Fernandez, Moira Sauane, Columba de la Parra   +6 more
doaj   +1 more source

Paracrine Signaling from Breast Cancer Cells Causes Activation of ID4 Expression in Tumor-Associated Macrophages

Cells, 2020
Background: Tumor-associated macrophages (TAMs) constitute a major portion of the leukocyte infiltrate found in breast cancer (BC). BC cells may reprogram TAMs in a pro-angiogenic and immunosuppressive sense.
Sara Donzelli, Andrea Sacconi, Chiara Turco, Enzo Gallo, Elisa Milano, Ilaria Iosue, Giovanni Blandino, Francesco Fazi, Giulia Fontemaggi   +8 more
doaj   +1 more source

Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion. [PDF]

, 2016
Estrogen receptor (ER)-negative cancers have a poor prognosis, and few targeted therapies are available for their treatment. Our previous analyses have identified potential kinase targets critical for the growth of ER-negative, progesterone receptor (PR)-
Brown, Powel H, Chang, Jenny, Den Hollander, Petra, Fuqua, Suzanne, Hartman, Zachary C, Hill, Jamal, Hilsenbeck, Susan G, Kent Osborne, C, Mazumdar, Abhijit, Mills, Gordon B, Poage, Graham M, Shepherd, Jonathan, Tsimelzon, Anna, Zhang, Yun   +13 more
core   +2 more sources

Regulatory Effect of miR497-5p–CCNE1 Axis in Triple-Negative Breast Cancer Cells and Its Predictive Value for Early Diagnosis [Retraction]

Cancer Management and Research, 2023
Liu WW, Li WD, Zhang YJ, Zhang ML. Cancer Manag Res. 2021;13:439–447. Following publication of the article, the authors raised concerns over the duplication of the two bar charts in Figure 5D.
Liu WW, Li WD, Zhang YJ, Zhang ML
doaj  

Association of Vitamin D3 Level with Breast Cancer Risk and Prognosis in African-American and Hispanic Women. [PDF]

, 2017
Background: This study investigated the association of vitamin D3 levels with breast cancer risk and progression in African-Americans and Hispanics. Methods: A total of 237 African-American (Cases = 119, Control = 118) and 423 Hispanic women (Cases = 124,
Chlebowski, Rowan, Clayton, Sheilah, Sarkissyan, Marianna, Vadgama, Jaydutt V, Wu, Yanyuan   +4 more
core   +2 more sources

HDAC inhibition potentiates immunotherapy in triple negative breast cancer. [PDF]

, 2017
Triple-negative breast cancer (TNBC) represents a more aggressive and difficult subtype of breast cancer where responses to chemotherapy occur, but toxicity is significant and resistance often follows. Immunotherapy has shown promising results in various
Ali, Niwa, Budillon, Alfredo, Krings, Gregor, Munster, Pamela N, Park, Jeenah, Pawlowska, Nela, Rosenblum, Michael D, Terranova-Barberio, Manuela, Thomas, Scott   +8 more
core   +1 more source