Results 201 to 210 of about 31,865 (216)
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European Urology, 1999
Over several decades, in vitro experimental studies have demonstrated that retinoids effect the process of carcinogenesis and tend towards the alteration of cells back to more normal differentiation. This hypothesis has formed the basis of several chemopreventive studies in breast cancer, cervical cancer, head and neck cancer and lung cancer ...
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Over several decades, in vitro experimental studies have demonstrated that retinoids effect the process of carcinogenesis and tend towards the alteration of cells back to more normal differentiation. This hypothesis has formed the basis of several chemopreventive studies in breast cancer, cervical cancer, head and neck cancer and lung cancer ...
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2008
Publisher Summary This chapter defines chemoprevention as an attempt that involves use of natural or synthetic chemical agents to avoid cancer. The most promising targets for cancer chemoprevention so far discovered are ligands for nuclear receptors, anti-anflammatory agents, chromatin modifiers, and processes leading to the generation of free ...
Carmen Avendaño, J. Carlos Menéndez
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Publisher Summary This chapter defines chemoprevention as an attempt that involves use of natural or synthetic chemical agents to avoid cancer. The most promising targets for cancer chemoprevention so far discovered are ligands for nuclear receptors, anti-anflammatory agents, chromatin modifiers, and processes leading to the generation of free ...
Carmen Avendaño, J. Carlos Menéndez
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Chemoprevention of Lung Cancer
Current Opinion in Pulmonary Medicine, 2004Lung cancer is one of the major causes of cancer-related deaths. Grim mortality figures argue powerfully for new approaches to control this disease. Chemoprevention is the use of specific natural or synthetic chemical agents to reverse, suppress, or prevent carcinogenic progression to invasive cancer.
Fadlo R. Khuri, Victor Cohen
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2010
Cancer chemoprevention is the use of natural or synthetic compounds to prevent, suppress, or reverse the development of invasive carcinoma. Thus, the goal of chemoprevention is to reduce the occurrence of cancer by inhibiting or inducing key critical pathways that play a role in the carcinogenesis process.
H. Mukhtar, N. Khan
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Cancer chemoprevention is the use of natural or synthetic compounds to prevent, suppress, or reverse the development of invasive carcinoma. Thus, the goal of chemoprevention is to reduce the occurrence of cancer by inhibiting or inducing key critical pathways that play a role in the carcinogenesis process.
H. Mukhtar, N. Khan
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Cytochrome P450s and chemoprevention
Biochemical Society Transactions, 2000The cytochrome P450 mono-oxygenase system represents a major defence against chemical challenge from the environment, constituting part of an adaptive response mounted by an organism following exposure to harmful agents. Cytochrome P450s are also able to catalyse the activation of compounds to toxic products, and participate in a variety of essential ...
Henderson, C J, Sahraouei, A, Wolf, C R
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Chemoprevention of breast cancer
Breast Cancer Research and Treatment, 1989The hypothesis that oestrogen is an important promoter of human breast cancer raises the possibility that endocrine intervention could prevent the disease. Various methods of reducing oestrogenic activity have been proposed including dietary control, progestin therapy, and ovarian ablation.
Powles, TJ +11 more
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Prostate cancer — chemoprevention
European Journal of Cancer, 2009Cancer prevention has been sub-classified as follows: • Primary prevention: intervention to prevent the occurrence of cancer in healthy people. • Secondary prevention: intervention in the subclinical phase, no cancer diagnosed, prevent disease in an ‘at risk’ population. • Tertiary prevention: alter the course of minimal clinical disease.
Wytske M. van Weerden +1 more
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Chemoprevention of Prostate Cancer
Annual Review of Medicine, 2005Prostate cancer is an attractive target for chemoprevention because of its ubiquity, treatment-related morbidity, long latency between premalignant lesions and clinically evident cancer, and defined molecular pathogenesis. The Prostate Cancer Prevention Trial has provided the first firm evidence that this cancer can be prevented by a relatively ...
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Preclinical Development of Chemopreventive Agents for Chemoprevention
2017Chemopreventive agents regulate cellular and molecular events by modulation of phase I and phase II metabolizing enzymes inducing DNA repair and inhibiting growth and cell cycle progression and differentiation and apoptosis, growth hormonal activity modulation, ligands for nuclear receptors, and alteration of chromatin structure.
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European Journal of Cancer Prevention, 1994
Cancer chemoprevention is in a phase of extensive development, and the results achieved so far are particularly promising in the field of lung and upper aerodigestive tract carcinogenesis.
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Cancer chemoprevention is in a phase of extensive development, and the results achieved so far are particularly promising in the field of lung and upper aerodigestive tract carcinogenesis.
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