Results 71 to 80 of about 70,358 (244)

The PPARγ Agonist Rosiglitazone Suppresses Syngeneic Mouse SCC (Squamous Cell Carcinoma) Tumor Growth through an Immune-Mediated Mechanism [PDF]

, 2019
Recent evidence suggests that PPARγ agonists may promote anti-tumor immunity. We show that immunogenic PDV cutaneous squamous cell carcinoma (CSCC) tumors are rejected when injected intradermally at a low cell number (1 × 106) into immune competent ...
Derr-Yellin, Ethel, Ermatov, Nurmukambed, Konger, Raymond L., Ren, Lu, Sahu, Ravi P.   +4 more
core   +1 more source

Comparative Profiling of Capsicum frutescens and C. annuum Reveals Superior Bioactivities and Nutritional Advantages for Functional Food Applications

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Systematic bioactivity profiling revealed C. frutescens demonstrated significantly superior radical scavenging capacity (DPPH IC50: 111.96 ± 3.24 μg/mL; 2.5‐fold enhancement, p < 0.001), enhanced broad‐spectrum antibacterial efficacy (zone diameters: 8–22 mm), and notable cytotoxic activity meeting NCI preliminary criteria (LC50: 29.24 ± 1.15 μg/mL ...
Shahin Akter, Muhammad Mamunur Rashid Mahib, Mohammad Razuanul Hoque, Md. Rafiqul Islam, Md. Golam Kabir   +4 more
wiley   +1 more source

Qualitative analysis of shared decision-making for chemoprevention in the primary care setting: provider-related barriers

BMC Medical Informatics and Decision Making, 2022
Background Chemoprevention with anti-estrogens, such as tamoxifen, raloxifene or aromatase inhibitors, have been shown to reduce breast cancer risk in randomized controlled trials; however, uptake among women at high-risk for developing breast cancer ...
Tarsha Jones, Thomas Silverman, Ashlee Guzman, Julia E. McGuinness, Meghna S. Trivedi, Rita Kukafka, Katherine D. Crew   +6 more
doaj   +1 more source

Possible Roles for Essential Oils in Chemoprevention and Suppression of Cancer [PDF]

, 2020
Cancer represents one of the costliest and most prevalent diseases to afflict the modern world, even though treatments have evolved steadily over the years and produce an increasingly positive outlook with each development and innovation.
Lillestolen, Chad Kirk
core   +1 more source

Violacein, an indole-derived purple-colored natural pigment produced by Janthinobacterium lividum, inhibits the growth of head and neck carcinoma cell lines both in vitro and in vivo [PDF]

, 2015
Violacein (VIO; 3-[1,2-dihydro-5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-ylidene]-1,3-dihydro-2H-indol-2-one), an indole-derived purple-colored pigment, produced by a limited number of Gram-negative bacteria species, including Chromobacterium ...
Bei, Roberto, Benvenuto, Monica, DI STEFANO, Enrica, Fantini, Massimo, LA REGINA, Giuseppe, Manzari, Vittorio, Masuelli, Laura, Mattei, Maurizio, Mattera, Rosanna, Modesti, Andrea, Pantanella, Fabrizio, Schippa, Serena, Silvestri, Romano   +12 more
core   +1 more source

Preparation and Performance of Phthalocyanine @ Copper Iodide Cluster Nanoparticles for X-Ray-Induced Photodynamic Therapy

Molecules
The efficacy of X-ray-induced photodynamic therapy (X-PDT) for deep tumors is often hindered by conventional scintillators, typically rare-earth nanoparticles plagued by long-term toxicity and suboptimal scintillation yields.
Wei Xie, Yunan Li, Guoyan Tang, Zhihua Li, Mengyu Yao, Biyuan Zheng, Xingshu Li, Jian-Dong Huang   +7 more
doaj   +1 more source

Oral cancer in the UK: to screen or not to screen. [PDF]

, 1998
Although oral squamous cell carcinoma accounts for only a small proportion of malignant neoplasms in the UK, oral cancer incidence and mortality rates have been rising in recent years.
Rodrigues, Veena
core  

Clinical Features Associated With Malignant Transformation of Low‐Grade Dysplasia

Journal of Oral Pathology &Medicine, Volume 55, Issue 1, Page 99-106, January 2026.
ABSTRACT Background Inferring risk for malignant transformation (MT) in patients with lesions diagnosed as mild or moderate oral epithelial dysplasia (low‐grade OED) remains challenging. We developed two models assessing the risk of progression to high‐grade OED (severe dysplasia or carcinoma in situ) or OSCC in patients with low‐grade OED lesions ...
Denise M. Laronde, Matt Berkowitz, A. Ross Kerr, Erinn M. Hade, Mutita Siriruchatanon, Miriam P. Rosin, Stella K. Kang   +6 more
wiley   +1 more source

Discovery of pyroptosis-inducing natural products in neuroblastomas: computational studies with experimental validation

BMC Complementary Medicine and Therapies
Background Neuroblastomas evade apoptosis due to oncogene mutations and antiapoptotic proteins, necessitating novel therapeutics that work in concert with other forms of cell death.
Beni Lestari, Rohmad Yudi Utomo, Faaza Aulia Rahman, Dyaningtyas Dewi Pamungkas Putri, Ummi Maryam Zulfin, Yusuke Suenaga, Edy Meiyanto, Yoshitaka Hippo   +7 more
doaj   +1 more source

Breast Cancer Profile among Patients with a History of Chemoprevention

International Journal of Breast Cancer, 2016
Purpose. This study identifies women with breast cancer who utilized chemoprevention agents prior to diagnosis and describes their patterns of disease. Methods.
Freya R. Schnabel, Sarah Pivo, Jennifer Chun, Shira Schwartz, Ana Paula Refinetti, Deborah Axelrod, Amber Guth   +6 more
doaj   +1 more source