Results 51 to 60 of about 25,830 (181)

Natural Products as Cancer Chemo Preventive Agents: Where We Stand

Natural Product Communications, 2022
This work briefly reviews cancer chemoprevention. This is a very challenging field, as products with a high level of toxicity such as chemotherapeutic agents may be proposed and accepted only under life-threatening conditions.
Alberto Boretti
doaj   +1 more source

Molecular descriptor driven QSPR modeling of Papp, TEER and Efflux Ratio from Caco‐2 cells using machine learning for various phytochemicals

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6606-6616, 30 August 2026.
Abstract BACKGROUND The present study aimed to develop and validate quantitative structure–property relationship (QSPR) models for predicting permeability related bioavailability indicators including apparent permeability (Papp), trans‐epithelial electrical resistance (TEER) and efflux ratio (ER) based on molecular descriptors (n = 5003) of 83 ...
Jin‐Woo Kim, Rixing Cong, Jin‐Soo Park, Keunwan Park, Kyungsu Kang, Soon‐Mi Shim   +5 more
wiley   +1 more source

Phthalocyanine aggregates as semiconductor-like photocatalysts for hypoxic-tumor photodynamic immunotherapy

Nature Communications
Photodynamic immunotherapy (PIT) has emerged as a promising approach for efficient eradication of primary tumors and inhibition of tumor metastasis. However, most of photosensitizers (PSs) for PIT exhibit notable oxygen dependence.
Hao Liu, Ziqing Li, Xiaojun Zhang, Yihui Xu, Guoyan Tang, Zhaoxin Wang, Yuan-Yuan Zhao, Mei-Rong Ke, Bi-Yuan Zheng, Shuping Huang, Jian-Dong Huang, Xingshu Li   +11 more
doaj   +1 more source

Dietary Terpenoids in Advancing Biofilm‐Mediated Cancer Prevention: Antibiofilm Cascade, Molecular Crosstalk, and Nano‐Facilitated Functional Delivery

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT The role of microbes in cancer is gaining attention these days, especially in the context of tumor‐associated biofilms and dysbiotic microbiota. Biofilm‐producing microorganisms, such as Fusobacterium nucleatum and Helicobacter pylori, trigger oncogenic inflammation and immune evasion in tumor initiation and progression, and in the development
Saikat Mazumder, Aditi Dey, Debasmita Bhattacharya, Dibyajit Lahiri, Moupriya Nag, Sudhriti Maity, Navin Kumar, Soumya Pandit, Vaseem Raja, Shubham Sharma, Shashi Prakash Dwivedi, Mithul Rajeev, Juwita Ratna Dewi, Lola Sanayeva, Dilbar Azimova   +14 more
wiley   +1 more source

Study protocol: Randomized controlled trial of web-based decision support tools for high-risk women and healthcare providers to increase breast cancer chemoprevention

Contemporary Clinical Trials Communications, 2019
Background: Chemoprevention using selective estrogen receptor modulators and aromatase inhibitors has been shown to reduce invasive breast cancer incidence in high-risk women.
Katherine D. Crew, Thomas B. Silverman, Alejandro Vanegas, Meghna S. Trivedi, Jill Dimond, Jennie Mata, Margaret Sin, Tarsha Jones, Mary Beth Terry, Wei-Yann Tsai, Rita Kukafka   +10 more
doaj   +1 more source

Physapubescin B From Physalis: A Food‐Derived Withanolide for Cancer Chemoprevention and Nutraceutical Development

eFood, Volume 7, Issue 4, August 2026.
Physapubescin B may interfere with multiple cancer‐associated signaling pathways by inhibiting Ras/Raf/mitogen‐activated protein kinase kinase/extracellular signal‐regulated kinase (Ras/Raf/MEK/ERK) signaling and vascular endothelial growth factor (VEGF)‐dependent angiogenesis.
Wojciech Koch, Katarzyna Stępnik, Anna Wawruszak, Estera Okoń, Agata Jarząb, Katarzyna Gaweł‐Bęben, Magdalena Michalak‐Tomczyk, Jacek Jachuła, Magdalena Zdziebło, Paweł Helon, Javad Sharifi‐Rad, Daniela Calina   +11 more
wiley   +1 more source

Qualitative analysis of shared decision-making for chemoprevention in the primary care setting: provider-related barriers

BMC Medical Informatics and Decision Making, 2022
Background Chemoprevention with anti-estrogens, such as tamoxifen, raloxifene or aromatase inhibitors, have been shown to reduce breast cancer risk in randomized controlled trials; however, uptake among women at high-risk for developing breast cancer ...
Tarsha Jones, Thomas Silverman, Ashlee Guzman, Julia E. McGuinness, Meghna S. Trivedi, Rita Kukafka, Katherine D. Crew   +6 more
doaj   +1 more source

Geostatistical Modelling and Web‐Based Mapping of Malaria Risks Among Children Under Five Years in Nigeria: Evidence From the 2021 Nigeria Malaria Indicator Survey

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Malaria is a critical public health concern in Nigeria with the country bearing an uneven burden of the disease. In Nigeria, malaria is one of the main causes of child mortality and despite all efforts to reduce malaria mortality rates, the disease remains a major concern, notably among children under‐fives.
Justice Moses K. Aheto, Bakare Emmanuel Afolabi, Dolapo O. Oniyelu, Deborah O. Daniel, Steven I. Ikediashi, Oluwaseun A. Mogbojuri, Ronke D. Olorunfemi, Sodiq A. Orogun, Afeez Abidemi, Idowu I. Olasupo, Samuel A. Osikoya, Samuel A. Adeyemi, Hapiness O. Ismail, Isaac Bakare, Samson O. Olagbami, Dolapo A. Bakare, Baiyeri Samuel, Temitayo V. Irewole, Oluwafunmilayo O. Olapade, Oluwafolakemi Odunola, Oghenekevwe R. Ajewole, Joshua P. Ojo, Segun Oyedeji, Wisdom Takramah   +23 more
wiley   +1 more source

Breast Cancer Profile among Patients with a History of Chemoprevention

International Journal of Breast Cancer, 2016
Purpose. This study identifies women with breast cancer who utilized chemoprevention agents prior to diagnosis and describes their patterns of disease. Methods.
Freya R. Schnabel, Sarah Pivo, Jennifer Chun, Shira Schwartz, Ana Paula Refinetti, Deborah Axelrod, Amber Guth   +6 more
doaj   +1 more source

Development and Usability Testing of an Information Needs‐Based Chatbot for Individuals With Pathogenic Variants in BRCA Genes in Korea: A Methodological Study

Journal of Genetic Counseling, Volume 35, Issue 4, August 2026.
ABSTRACT Korean individuals with BRCA pathogenic/likely pathogenic (P/LP) variants have limited access to genetic counseling due to shortages of genetic professionals and lack of reimbursement. Despite the growing interest in digital health interventions, few digital counseling support tools have been designed to address the diverse information needs ...
Sun‐Young Park, Youlim Kim, Maria C. Katapodi, Sue Kim   +3 more
wiley   +1 more source