Results 41 to 50 of about 37,862 (221)

Cancer chemoprevention

BMJ, 2002
Chemoprevention means prevention of cancer by administering chemical compounds. Ideal chemopreventive agents are non-toxic, inexpensive and can be taken orally. A large number of natural and synthetic compounds have cancer preventive properties in cell culture or animal model studies.
openaire   +5 more sources

Cancer Chemoprevention With Nuts [PDF]

JNCI Journal of the National Cancer Institute, 2014
It is well established that increased nut consumption is associated with a reduced risk of major chronic diseases, such as cardiovascular disease and type 2 diabetes mellitus. On the other hand, the association between nut consumption and cancer mortality is less clear.
Falasca M, Casari I, Maffucci T
openaire   +3 more sources

Nephroprotective effects of cardamom essential oil (Amomum compactum Soland. Ex Maton) on kidney cells

Indonesian Journal of Biotechnology, 2023
Many chemotherapeutic agents cause various side effects, including nephrotoxicity. Cardamom essential oil (Amomum compactum Soland. ex Maton) contains compounds that exhibit antioxidant activity, such as 1,8‐cineole, α‐pinene, α‐terpineol, and linalool ...
Nisa Ul Hasanah, Ahmad Syauqy Tafrihani, Ummi Maryam Zulfin, Dhiya Ulhaq Salsabila, Ratih Kurnia Wardani, Muthi' Ikawati, Edy Meiyanto, Riris Istighfari Jenie   +7 more
doaj   +1 more source

Natural flavonoid Orientin restricts 5-Fluorouracil induced cancer stem cells mediated angiogenesis by regulating HIF1α and VEGFA in colorectal cancer

Molecular Medicine
Background Cancer stem cells are a small subpopulation of cells which are responsible for tumor metastasis, angiogenesis, drug resistance etc. 5-Fluorouracil (5FU), a common therapeutic drug used in colorectal cancer treatment is reported to enrich CSCs,
Rituparna Ghosh, Arijit Bhowmik, Souradeep Biswas, Priya Samanta, Rupali Sarkar, Shampa Pakhira, Mrinmoyee Mondal, Subhadip Hajra, Prosenjit Saha   +8 more
doaj   +1 more source

Design and synthesis of coumarin-based organoselenium as a new hit for myeloprotection and synergistic therapeutic efficacy in adjuvant therapy

Scientific Reports, 2018
A newly designed organoselenium compound, methyl substituted umbelliferone selenocyanate (MUS), was synthesized as a primary hit against the myelotoxic activity of carboplatin. MUS was administered at 6 mg/kg b.wt, p.o.
Arup Ranjan Patra, Somnath Singha Roy, Abhishek Basu, Avishek Bhuniya, Arin Bhattacharjee, Subhadip Hajra, Ugir Hossain Sk, Rathindranath Baral, Sudin Bhattacharya   +8 more
doaj   +1 more source

Survival Outcomes in Older Adults With Axial Spondyloarthritis and Concomitant Cancer

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman, Mei Li, Xiudong Lei, Hui Zhao, Juan I. Ruiz, Sharon H. Giordano, Alexis R. Ogdie, Maria E. Suarez‐Almazor   +7 more
wiley   +1 more source

CANCER CHEMOPREVENTION

, 1998
Cancer chemoprevention uses noncytotoxic drugs or nutrients to prevent, retard, or delay carcinogenesis. The future of cancer chemoprevention depends on understanding key cellular growth and proliferation-controlling events, developing markers of ...
Dean E. Brenner, Koyamangalath Krishnan, Ruffin, M T., Brenner, D E., Mack T. Ruffin IV, Krishnan, K   +5 more
core   +1 more source

Harnessing Methylselenol (CH3SeH): A Highly Effective Platform for Stimuli‐Responsive Delivery With Therapeutic Potential

Advanced Science, EarlyView.
Tools for controlled selenol delivery are crucial for exploring Se‐related biology and medicine, but compound platforms for triggerable release of CH3SeH remain lacking. Herein, we report the first general triggered platform (TD‐MSe) for efficient cyclization release of CH3SeH in live cells.
Wenfang Liang, Liyue Wang, Xuan Wang, Xinran Li, Hao Xing, Lu Sun, Zhen Xi, Long Yi   +7 more
wiley   +1 more source

Exosome-sheathed porous silica nanoparticle-mediated co-delivery of 3,3′-diindolylmethane and doxorubicin attenuates cancer stem cell-driven EMT in triple negative breast cancer

Journal of Nanobiotechnology
Background Therapeutic management of locally advanced and metastatic triple negative breast cancer (TNBC) is often limited due to resistance to conventional chemotherapy.
Rupali Sarkar, Souradeep Biswas, Rituparna Ghosh, Priya Samanta, Shampa Pakhira, Mrinmoyee Mondal, Yashaswi Dutta Gupta, Suman Bhandary, Prosenjit Saha, Arijit Bhowmik, Subhadip Hajra   +10 more
doaj   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source