Results 21 to 30 of about 61,449 (214)

Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer. [PDF]

, 2014
Preventing breast cancer is an effective strategy for reducing breast cancer deaths. The purpose of chemoprevention (also termed preventive therapy) is to reduce cancer incidence by use of natural, synthetic, or biological agents.
Brown, Powel H, Litzenburger, Beate C
core   +1 more source

Preparation and Cytotoxic Evaluation of PGV-1 Derivative, CCA-1.1, as a New Curcumin Analog with Improved-Physicochemical and Pharmacological Properties [PDF]

Advanced Pharmaceutical Bulletin, 2022
Purpose: This study aimed to challenge the anticancer potency of pentagamavunone-1 (PGV-1) and obtain a new compound (Chemoprevention-Curcumin Analog 1.1, CCA-1.1) withimproved chemical and pharmacological properties.Methods: CCA-1.1 was prepared by ...
Rohmad Yudi Utomo, Febri Wulandari, Dhania Novitasari, Beni Lestari, Ratna Asmah Susidarti, Riris Istighfari Jenie, Jun-ya Kato, Sardjiman Sardjiman, Edy Meiyanto   +8 more
doaj   +1 more source

Antimutagenic and antioxidant activity of a protein fraction from aerial parts of Urtica dioica [PDF]

, 2014
Context: Urtica dioica L. (Urticaceae), stinging nettle, has been employed as a folklore remedy for a wide spectrum of ailments, including urinary disorders, prostatic hyperplasia, and liver diseases.
DI GIACOMO, Silvia, DI SOTTO, Antonella, Mazzanti, Gabriela, N., Savickiene, R., Staršelskytė, V., Baksenskaite, Vitalone, Annabella   +6 more
core   +1 more source

PGV-1 Causes Disarrangement of Spindle Microtubule Organization Resulting in Aberrant Mitosis in HLF and HuH6 Cells Associated with Altered MYCN Status [PDF]

Advanced Pharmaceutical Bulletin
Purpose: The HLF and HuH-6 cell lines represent hepatocellular carcinoma (HCC) with different characteristics in chromosome content that may give different drug responses. Here, PGV-1 was intended to challenge the growth-suppressing effect on HLF and HuH-
Nadzifa Nugraheni, Ummi Maryam Zulfin, Beni Lestari, Novia Permata Hapsari, Muthi Ikawati, Rohmad Yudi Utomo, Yusuke Suenaga, Yoshitaka Hippo, Edy Meiyanto   +8 more
doaj   +1 more source

Understanding low chemoprevention uptake by women at high risk of breast cancer: findings from a qualitative inductive study of women’s risk-reduction experiences

BMC Women's Health, 2021
Background Chemoprevention is one of several methods that have been developed to help high-risk women reduce their risk of breast cancer. Reasons for the low uptake of chemoprevention are poorly understood. This paper seeks a deeper understanding of this
Tasleem J. Padamsee, Megan Hils, Anna Muraveva   +2 more
doaj   +1 more source

Two Active Compounds from Caesalpinia sappan L. in Combination with Cisplatin Synergistically Induce Apoptosis and Cell Cycle Arrest on WiDr Cells [PDF]

Advanced Pharmaceutical Bulletin, 2017
Purpose: The aim of this study is to observe the synergistic effect of two active compounds of secang, brazilin and brazilein, combined with cisplatin on WiDr colon cancer cells. Methods: Cytotoxic activities of brazilin (Bi) and brazilein (Be) in single
Sri Handayani, Ratna Asmah Susidarti, Riris Istighfari Jenie, Edy Meiyanto   +3 more
doaj   +1 more source

Anticancer efficacy of phenolics based structurally related compounds and their radical scavenging action [PDF]

, 2011
Cancer, one of the leading causes of death worldwide, is an abnormal cell proliferation that fails to respond to the normal signals. In an effort to eradicate the growing menace of cancer, a clear understanding of fundamental biology and molecular ...
Arvind S. Negi, Nusrat Masood, Suaib Luqman, Vijaya Dubey   +3 more
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Current chemoprevention approaches in Lynch syndrome and Familial adenomatous polyposis: a global clinical practice survey

Frontiers in Oncology, 2023
BackgroundInternational chemoprevention preferences and approaches in Lynch syndrome (LS) and APC-associated polyposis, including Familial adenomatous polyposis (FAP) and attenuated FAP (AFAP) have not been previously explored.AimTo describe current ...
Kathryn A. Mraz, Kathryn A. Mraz, Rachel Hodan, Linda Rodgers-Fouche, Sanjeevani Arora, Francesc Balaguer, Jose G. Guillem, Joanne M. Jeter, Priyanka Kanth, Dan Li, David Liska, Joshua Melson, Kimberly Perez, Charite Ricker, Brian H. Shirts, Eduardo Vilar, Bryson W. Katona, Mev Dominguez-Valentin   +17 more
doaj   +1 more source

Phytoestrogens [PDF]

, 2004
Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals.
Adlercreutz H, Alekel DL, Bhathena SJ, Bielenberg J, Biendl M, Boller B, Dai Q, Day JK, de Kleijn MJJ, den Tonkelaar I, denTonkelaar I, Dewick PM, Ebisawa H, Fritz WA, Guo TL, Hodgson JM, Horn-Ross PL, ILDIS, Kim CS, Lamartiniere CA, Maggiolini M, Maskarinec G, McCann SE, Mentor MR, MerzDemlow BE, Newbold RR, Pan W, Peluso MR, Richard A. Dixon, Seested S, Setchell KDR, Setchell KDR, Setchell KDR, Slavin JL, Stevens JF, Whitten PL, Yanagihara K, Zhang Y   +37 more
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Malaria chemoprevention and drug resistance: a review of the literature and policy implications

Malaria Journal, 2022
Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-malarial drugs used for chemoprevention is perennially threatened by drug resistance.
Christopher V. Plowe
doaj   +1 more source