Results 21 to 30 of about 25,830 (181)

Two Active Compounds from Caesalpinia sappan L. in Combination with Cisplatin Synergistically Induce Apoptosis and Cell Cycle Arrest on WiDr Cells [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2017
Purpose: The aim of this study is to observe the synergistic effect of two active compounds of secang, brazilin and brazilein, combined with cisplatin on WiDr colon cancer cells. Methods: Cytotoxic activities of brazilin (Bi) and brazilein (Be) in single
Sri Handayani   +3 more
doaj   +1 more source

Current chemoprevention approaches in Lynch syndrome and Familial adenomatous polyposis: a global clinical practice survey

open access: yesFrontiers in Oncology, 2023
BackgroundInternational chemoprevention preferences and approaches in Lynch syndrome (LS) and APC-associated polyposis, including Familial adenomatous polyposis (FAP) and attenuated FAP (AFAP) have not been previously explored.AimTo describe current ...
Kathryn A. Mraz   +17 more
doaj   +1 more source

Understanding low chemoprevention uptake by women at high risk of breast cancer: findings from a qualitative inductive study of women’s risk-reduction experiences

open access: yesBMC Women's Health, 2021
Background Chemoprevention is one of several methods that have been developed to help high-risk women reduce their risk of breast cancer. Reasons for the low uptake of chemoprevention are poorly understood. This paper seeks a deeper understanding of this
Tasleem J. Padamsee   +2 more
doaj   +1 more source

Malaria chemoprevention and drug resistance: a review of the literature and policy implications

open access: yesMalaria Journal, 2022
Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-malarial drugs used for chemoprevention is perennially threatened by drug resistance.
Christopher V. Plowe
doaj   +1 more source

Redox/NIR dual-responsive MoS2 for synergetic chemo-photothermal therapy of cancer

open access: yesJournal of Nanobiotechnology, 2019
Background The construction of a multifunctional drug delivery system with a variety of advantageous features, including targeted delivery, controlled release and combined therapy, is highly attractive but remains a challenge.
Jian Liu   +5 more
doaj   +1 more source

Chemoprevention of Melanoma [PDF]

open access: yes, 2012
Despite advances in drug discovery programs and molecular approaches for identifying drug targets, incidence and mortality rates due to melanoma continue to rise at an alarming rate. Existing preventive strategies generally involve mole screening followed by surgical removal of the benign nevi and abnormal moles.
Subbarao V, Madhunapantula   +1 more
openaire   +2 more sources

Recent advances of sorafenib nanoformulations for cancer therapy: Smart nanosystem and combination therapy

open access: yesAsian Journal of Pharmaceutical Sciences, 2021
Sorafenib, a molecular targeted multi-kinase inhibitor, has received considerable interests in recent years due to its significant profiles of efficacy in cancer therapy.
Fangmin Chen   +5 more
doaj   +1 more source

NSAIDs and Chemoprevention [PDF]

open access: yesCurrent Cancer Drug Targets, 2004
Several epidemiological, clinical and experimental studies established nonsteroidal anti-inflammatory drugs (NSAIDs) as promising cancer chemopreventive agents. Long-term use of aspirin and other NSAIDs has been shown to reduce the risk of cancer of the colon and other gastrointestinal organs as well as of cancer of the breast, prostate, lung, and skin.
Chinthalapally V, Rao, Bandaru S, Reddy
openaire   +2 more sources

Cancer chemoprevention

open access: yesBMJ, 2002
Chemoprevention means prevention of cancer by administering chemical compounds. Ideal chemopreventive agents are non-toxic, inexpensive and can be taken orally. A large number of natural and synthetic compounds have cancer preventive properties in cell culture or animal model studies.
openaire   +5 more sources

Cancer Chemoprevention With Nuts [PDF]

open access: yesJNCI Journal of the National Cancer Institute, 2014
It is well established that increased nut consumption is associated with a reduced risk of major chronic diseases, such as cardiovascular disease and type 2 diabetes mellitus. On the other hand, the association between nut consumption and cancer mortality is less clear.
Falasca M, Casari I, Maffucci T
openaire   +3 more sources

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