Results 11 to 20 of about 29,943 (226)

The intention to receive tuberculosis preventive therapy in adult household contacts of pulmonary TB patients in Delhi, India

Journal of Infection in Developing Countries, 2022
Introduction: The integration of newer tuberculosis preventive therapy regimens, which have shorter treatment duration, simpler dosing requirements, and improved safety profile, is being considered within India’s national tuberculosis elimination ...
Nandini Sharma, Saurav Basu, Ashwani Khanna, Pragya Sharma, Shivani Chandra   +4 more
doaj   +1 more source

Chemoprophylactic Assessment of Combined Intranasal SARS-CoV-2 Polymerase and Exonuclease Inhibition in Syrian Golden Hamsters

Viruses, 2023
Pibrentasvir (PIB) has been demonstrated to block exonuclease activity of the SARS-CoV-2 polymerase, protecting favipiravir (FVP) and remdesivir (RDV) from post-incorporation excision and eliciting antiviral synergy in vitro.
Eduardo Gallardo-Toledo, Megan Neary, Joanne Sharp, Joanne Herriott, Edyta Kijak, Chloe Bramwell, Paul Curley, Usman Arshad, Henry Pertinez, Rajith K. R. Rajoli, Anthony Valentijn, Helen Cox, Lee Tatham, Anja Kipar, James P. Stewart, Andrew Owen   +15 more
doaj   +1 more source

The Biological and Clinical Aspects of a Latent Tuberculosis Infection

Tropical Medicine and Infectious Disease, 2022
Tuberculosis (TB), caused by bacilli from the Mycobacterium tuberculosis complex, remains a serious global public health problem, representing one of the main causes of death from infectious diseases.
Nelli F. Khabibullina, Daria M. Kutuzova, Irina A. Burmistrova, Irina V. Lyadova   +3 more
doaj   +1 more source

Chemoprophylaxis and Malaria Death Rates

Emerging Infectious Diseases, 2006
To determine the effect of chemoprophylaxis on the case-fatality rate of malaria, we analyzed all cases of Plasmodium falciparum malaria in nonimmune persons reported from 1993 to 2004 in Germany.
Gérard Krause, Irene Schöneberg, Doris Altmann, Klaus Stark   +3 more
doaj   +1 more source

Arylimidamides Have Potential for Chemoprophylaxis against Blood-Transmitted Chagas Disease

Pathogens, 2023
Chagas disease (CD) affects over 6 million people worldwide and can be transmitted iatrogenically. Crystal violet (CV) was previously used for pathogen reduction but has harmful side-effects.
Bruno Lisboa Timm, Aline Nefertiti Silva da Gama, Marcos Meuser Batista, Denise da Gama Jaén Batista, David W. Boykin, Harry P. De Koning, Maria de Nazaré Correia Soeiro   +6 more
doaj   +1 more source

Malaria in Nonimmune Travelers [PDF]

, 1994
Background: With the current increase of international travel to tropical endemic areas, the incidence of malaria being imported into nonendemic countries has increased significantly.
Jelinek, Thomas, Löscher, Thomas, Nothdurft, H. D.   +2 more
core   +1 more source

Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters

Viruses, 2023
The successful development of a chemoprophylaxis against SARS-CoV-2 could provide a tool for infection prevention that is implementable alongside vaccination programmes.
Megan Neary, Joanne Sharp, Eduardo Gallardo-Toledo, Joanne Herriott, Edyta Kijak, Chloe Bramwell, Helen Cox, Lee Tatham, Helen Box, Paul Curley, Usman Arshad, Rajith K. R. Rajoli, Henry Pertinez, Anthony Valentijn, Kevin Dhaliwal, Frank Mc Caughan, James Hobson, Steve Rannard, Anja Kipar, James P. Stewart, Andrew Owen   +20 more
doaj   +1 more source

Chemoprophylaxis in surgery [PDF]

Postgraduate Medical Journal, 1976
Summary The literature on the prophylactic use in surgery of disinfectants, antibiotics and the chemotherapeutic agents is reviewed. It is concluded that there is little place for the routine use of antibiotics or chemotherapeutic agents except in a very few conditions.
openaire   +2 more sources

Invasive Group A Streptococcal Infections: Benefit of Clindamycin, Intravenous Immunoglobulins and Secondary Prophylaxis

Frontiers in Pediatrics, 2021
Introduction: Mortality associated with invasive group A streptococcal infections (iGAS) remains high among adults, with lower mortality in children. The added value of both clindamycin and immunoglobulins in such treatment is still controversial, as is ...
Delphine Laho, Delphine Laho, Sophie Blumental, Anne Botteaux, Pierre R. Smeesters, Pierre R. Smeesters, Pierre R. Smeesters, Pierre R. Smeesters   +7 more
doaj   +1 more source

What is the evidence for giving chemoprophylaxis to children or students attending the same preschool, school or college as a case of meningococcal disease? [PDF]

, 2011
We performed a systematic literature review to assess the effectiveness of chemoprophylaxis for contacts of sporadic cases of invasive meningococcal disease (IMD) in educational settings.
Ackerman, Barker, Bernabeu, Cartwright, Davison, Dawson, Favorova, Ferson, Fraser, G. HANQUET, Giovanetti, González de Aledo, Granerod, Hastings, Hoek, J. M. STUART, Jacobson, Juels, Norton, O'Donovan, P. STEFANOFF, Palau, Riordan, Robinson, S. HEUBERGER, S. NIELSEN, Scholten, Schubiger, Stefanoff, Sutton, W. HELLENBRAND   +30 more
core   +2 more sources