Results 191 to 200 of about 133,417 (336)

“Close Then Clear” Margins in Transoral Resection of p16+ Oropharyngeal Squamous Cell Carcinoma

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Standard 5‐mm surgical margins in the oropharynx are challenging due to the intimate relationship with neurovascular structures and patient function. De‐escalation of therapy with the acceptance of close surgical margins may improve functional patient outcomes.
Chrisje Den Besten   +8 more
wiley   +1 more source

Lymph Nodal Yield and Prediction of Mortality in Oral Squamous Cell Carcinoma Patients

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Lymph nodal yield (LNY) is increasingly used in oral squamous cell carcinoma (OSCC) research as a prognostic factor and quality metric but remain to be validated across independent OSCC cohorts. Study design Retrospective cohort study.
Christian Mirian   +10 more
wiley   +1 more source

Bridging the Gap: How Organ‐on‐a‐Chip Technology Facilitates the Battle against Glioma

open access: yesSmall Science, EarlyView.
This review critically evaluates current state‐of‐the‐art in vitro glioma models especially glioma‐on‐a‐chip models based on readout capability, performance, and physiological relevance. It summarizes the key parameters and proposes a practical framework to guide researchers in selecting the most suitable preclinical models for glioma studies.
Su Liu   +5 more
wiley   +1 more source

Preoperative (neoadjuvant) chemoradiotherapy in oesophageal cancer

open access: bronze, 2001
J I Geh, A. Crellin, Rob Glynne‐Jones
openalex   +1 more source

Pan‐ERBB Inhibitors Synergize With KRAS Inhibitors in Rectal Cancer

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Emerging RAS inhibitors show promise in treating KRAS‐mutated malignancies, but resistance mechanisms limit their clinical efficacy. Given recent clinical findings associating KRAS mutations with reduced response to neoadjuvant therapy in rectal cancer (RC), we aimed to investigate their impact on treatment outcomes and explore ...
Jonas Buchloh   +15 more
wiley   +1 more source

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