Results 31 to 40 of about 133,417 (336)
Adverse effects of chemoradiotherapy on invasion and metastasis of tumor cells
Genes and Diseases, 2020 The phenomenon of enhanced invasion and metastasis of residual tumor cells has been observed in an increasing number of patients receiving chemoradiotherapy recently, and tumor metastasis will undoubtedly limit patient prognosis.
Wei Xiong +4 more
doaj +1 more source
Prospective, open, multi-centre phase I/II trial to assess safety and efficacy of neoadjuvant radiochemotherapy with docetaxel and oxaliplatin in patients with adenocarcinoma of the oesophagogastric junction [PDF]
, 2013 Background: This phase I/II-trial assessed the dose-limiting toxicities (DLT) and maximum tolerated dose (MTD) of neoadjuvant radiochemotherapy (RCT) with docetaxel and oxaliplatin in patients with locally advanced adenocarcinoma of the oesophagogastric ...
Arnold, Dirk +12 more
core +1 more source
HeliyonSphingolipid metabolism affects prognosis and resistance to immunotherapy in patients with cancer and is an emerging target in cancer therapy with promising diagnostic and prognostic value.
Xiaolan He +6 more
doaj +1 more source
Emergency treatment of complicated colorectal cancer [PDF]
, 2018 Aim: To find evidence to suggest the best approach in patients admitted as an emergency for complicated colorectal cancer. Methods: The medical records of 131 patients admitted as an emergency with an obstructing, perforated, or bleeding colorectal ...
Brachini, Gioia +6 more
core +1 more source
Frontiers in Bioscience-LandmarkBackground: Breast cancer stem cells (BCSCs) are instrumental in treatment resistance, recurrence, and metastasis. The development of breast cancer and radiation sensitivity is intimately pertinent to long non-coding RNA (lncRNA). This
Yunbao Xu +3 more
doaj +1 more source
Exploring the Role of Ubiquitin-Proteasome System in the Pathogenesis of Parkinson’s Disease
PharmaceuticalsParkinson’s disease (PD) is a prevalent neurodegenerative disorder among the elderly population. The pathogenesis of PD encompasses genetic alterations, environmental factors, and age-related neurodegenerative processes.
Yiting Zhao +4 more
doaj +1 more source
Laryngeal Preservation Strategies in Locally Advanced Laryngeal and Hypopharyngeal Cancers. [PDF]
, 2019 For long, the treatment of locoregionally advanced laryngeal and hypopharyngeal squamous cell cancers (SCC) consisted of either total laryngectomy (TL) or definitive radiotherapy (RT).
Argiris, Athanassios +1 more
core +2 more sources
Discover OncologyBackground CD8T cells, also known as cytotoxic T lymphocytes, play a key role in the tumor immune microenvironment (TME) and immune response. The aim of this study was to explore the potential role of CD8T cell-associated biomarkers in predicting ...
Yu Zhang +3 more
doaj +1 more source
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
FEBS Open Bio, EarlyView.Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson +5 more
wiley +1 more source
Mandatory multidisciplinary approach for the evaluation of the lymph node status in rectal cancer [PDF]
, 2018 Colorectal cancer is the third most frequently reported malignancy and also the third leading cancer-related cause of death worldwide. Lymph node evaluation, both preoperatively and postoperatively, represents an important aspect of the diagnosis and ...
Ciorbagiu, Mihai C. +5 more
core +4 more sources