Results 31 to 40 of about 168,140 (338)

Adjuvant Capecitabine Following Concurrent Chemoradiotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma

JAMA Oncology, 2022
This multicenter, open-label randomized clinical trial conducted in China compares the efficacy and safety of adjuvant capecitabine with concurrent chemoradiotherapy vs concurrent chemoradiotherapy alone for treatment of patients with locoregionally ...
J. Miao, Lin Wang, S. Tan, Jin-Gao Li, J. Yi, E. Ong, L. Y. Tan, Ye Zhang, X. Gong, Qiu-Yan Chen, Yan-Qun Xiang, Ming-Yuan Chen, Ying Guo, X. Lv, W. Xia, Linquan Tang, Xiaowu Deng, Xiang Guo, F. Han, H. Mai, M. Chua, Chong Zhao   +21 more
semanticscholar   +1 more source

Suppression of the postoperative neutrophil leucocytosis following neoadjuvant chemoradiotherapy for rectal cancer and implications for surgical morbidity [PDF]

, 2010
Objective: The extent to which neoadjuvant chemoradio- therapy for rectal cancer influences postoperative morbid- ity is controversial. This study investigated whether this treatment suppresses the normal perioperative inflamma- tory response and ...
Anonymous, Artioukh, Bosset, Buie, Bujko, Bullard, Cohen, Gerard, Goldberg, Hartley, Kerr, Marijnen, Pahlman, Royal College of Pathologists Working Group on Cancer Services, Sauer, Wichmann, Wong   +16 more
core   +1 more source

Durvalumab after chemoradiotherapy in stage III non-small cell lung cancer.

Journal of Thoracic Disease, 2018
Immune Check Point inhibitors (ICIs) have demonstrated efficacy in advanced stage solid tumors including non-small cell lung cancer (NSCLC), CTLA4, programmed cell death-1 (PD-1) and PD-1 ligand 1 (PD-L1) inhibitors being the most studied drugs.
P. Tomasini, L. Greillier, Arnaud Boyer, Arnaud Jeanson, F. Barlesi   +4 more
semanticscholar   +1 more source

BRD4‐IRF1 axis regulates chemoradiotherapy‐induced PD‐L1 expression and immune evasion in non‐small cell lung cancer

Clinical and Translational Medicine, 2022
Background Chemoradiotherapy‐induced PD‐L1 upregulation leads to therapeutic resistance and treatment failure. The PD‐1/PD‐L1 blocking antibodies sensitize cancers to chemoradiotherapy by blocking extracellular PD‐1 and PD‐L1 binding without affecting ...
Jian Wang, Yingzhuo Xu, Xinrui Rao, Rui-guang Zhang, Jing Tang, Dan Zhang, Xiaohua Jie, K. Zhu, Xu Wang, Yunhong Xu, Sheng-tao Zhang, Xiaorong Dong, Zhang Tao, Kunyu Yang, Shuangbing Xu, R. Meng, Gang Wu   +16 more
semanticscholar   +1 more source

Morbidity and Mortality of Patients Who Underwent Minimally Invasive Esophagectomy After Neoadjuvant Chemoradiotherapy vs Neoadjuvant Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

JAMA Surgery, 2021
Key Points Question Is there any difference in the safety of neoadjuvant chemoradiotherapy (nCRT) followed by minimally invasive esophagectomy (MIE) for locally advanced esophageal squamous cell carcinoma (ESCC) compared with that of neoadjuvant ...
Hao Wang, Han Tang, Yong Fang, L. Tan, J. Yin, Yaxing Shen, Z. Zeng, Jiangyi Zhu, Yingyong Hou, M. Du, Jia Jiao, Hongjing Jiang, L. Gong, Zhigang Li, Jun Liu, D. Xie, Wenfeng Li, C. Lian, Qiang Zhao, Chun Chen, B. Zheng, Y. Liao, Kuo Li, Hecheng Li, Han-Yun Wu, L. Dai, Ke-Neng Chen   +26 more
semanticscholar   +1 more source

The relationship between systemic inflammation and stoma formation following anterior resection for rectal cancer: a cross-sectional study [PDF]

, 2017
Introduction: There is evidence that temporary defunctioning stoma formation in patients undergoing anterior resection reduces the risk of anastomotic leakage.
Horgan, Paul G., Khor, Bo Y., McMillan, Donald C., McSorley, Stephen T.   +3 more
core   +1 more source

Outcome of neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in non-metastatic locally advanced non-small cell lung cancer – A prospective and randomized study

Asian Journal of Medical Sciences, 2023
Background: Sequential chemoradiotherapy and concurrent chemoradiotherapy are two treatment options for locally advanced non-small cell lung cancer (NSCLC). Still there is limited data regarding which is the better treatment option.
Subir Pal , Anjan Bera , Soumen Mukherjee , Asmita Dasgupta , Srikrishna Mandal , Saptarshi Banerjee   +5 more
doaj   +1 more source

Induction chemotherapy in the treatment of nasopharyngeal carcinoma: Clinical outcomes and patterns of care [PDF]

, 2018
The role of induction chemotherapy in nasopharyngeal carcinoma (NPC) remains controversial. The primary aim of this study was to use the National Cancer Database to evaluate the patterns of care of induction chemotherapy in NPC and its impact on overall ...
Adkins, Douglas, Barnes, Justin, Daly, Mackenzie D, Gabani, Prashant, Gay, Hiram A, Lin, Alexander J, Oppelt, Peter, Rich, Jason T, Rudra, Soumon, Thorstad, Wade L, Zevallos, Jose P   +10 more
core   +2 more sources

KEYNOTE-975 study design: a Phase III study of definitive chemoradiotherapy plus pembrolizumab in patients with esophageal carcinoma

Future Oncology, 2021
Despite curative-intent treatment, most patients with locally advanced esophageal cancer will experience disease recurrence or locoregional progression, highlighting the need for new therapies. Current guidelines recommend definitive chemoradiotherapy in
M. Shah, J. Bennouna, T. Doi, L. Shen, Ken Kato, A. Adenis, H. Mamon, M. Moehler, Xiao-long Fu, B. Cho, Sonal Bordia, P. Bhagia, C. Shih, Anjali Desai, P. Enzinger   +14 more
semanticscholar   +1 more source

Current Oncological Treatment of Patients with Pancreatic Cancer in Germany: Results from a National Survey on behalf of the Arbeitsgemeinschaft Internistische Onkologie and the Chirurgische Arbeitsgemeinschaft Onkologie of the Germany Cancer Society [PDF]

, 2009
Background: No data have previously been available regarding the current treatment of patients with pancreatic cancer (PC) in German hospitals and medical practices.
Boeck, Stefan, Bruns, Christiane J., Heinemann, Volker, Jauch, Karl-Walter, Sargent, Mirja, Schäfer, Claus, Seufferlein, Thomas   +6 more
core   +1 more source