Results 141 to 150 of about 13,296 (264)

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

The Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu, Eduardo Bravo, George Bradley Richerson   +2 more
wiley   +1 more source

Origins of chemoreceptor curvature sorting in Escherichia coli

, 2017
Bacterial chemoreceptors organize into large clusters at the cell poles. Despite a wealth of structural and biochemical information on the system’s components, it is not clear how chemoreceptor clusters are reliably targeted to the cell pole.
Will Draper, Jan Liphardt
core   +1 more source

The role of group III/IV afferent feedback in the ventilatory, pressor and metabolic responses to exercise in normoxia and hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins, Phuong L. Ha, Connor A. Howe, Jay M. J. R. Carr, Justin A. Monteleone, Andrew J. M. Douglas, Abigail Nicholson, Andrew Steele, Brydie Lemkes, Jodie L. Koep, L. Madden Brewster, Jennifer Duffy, Mathew I. B. Debenham, Tena Monaghan, Declan Isaak, Jacob McCormick, Brian H. Dalton, Chris J. McNeil, Jared Baylis, David MacLeod, Mike Stembridge, Markus Amann, Philip N. Ainslie, Travis D. Gibbons   +23 more
wiley   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Respiratory control at high altitude: The chemoreceptor as a paragon of plasticity

The Journal of Physiology, EarlyView.
Jerome A. Dempsey
wiley   +1 more source

Effects of Oral Health and Functional Characteristics on Taste Sensitivity in Older Adults: Comparative Analysis Using Solution and Taste Strip Tests

Journal of Oral Rehabilitation, Volume 53, Issue 7, Page 1286-1295, July 2026.
Oral and functional status differentially modify gustatory assessment in older adults. Salivary and swallowing functions selectively affect strip and solution tests, respectively, highlighting the complementary roles of these methods for comprehensive evaluation and personalised management of taste dysfunction.
Hyo‐Jung Jung, Hye Jin Lee, Yehin Cho, Hyung‐Joon Ahn   +3 more
wiley   +1 more source

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1466-1475, June 2026.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher, John Mann, Anik Chaturbedi, Shilpa Chakravartula, Hamed Meshkin, Affan Affan, Alexander Galluppi, Ji Young Kim, Nigar Karimli, Yue Han, Zachary Dezman, Jeffry Florian, Zhihua Li   +12 more
wiley   +1 more source

Effect of Underwater Swimming on Physiological and Perceptual Parameters in Competitive Swimmers: A Comparison With Surface Swimming

European Journal of Sport Science, Volume 26, Issue 6, June 2026.
ABSTRACT In competition, swimmers alternate between swimming on the surface and underwater; they therefore train in apnea to improve their tolerance to lack of oxygen during exercise, even though research in this area remains limited. The aim of the study was to investigate the impact of underwater swimming on physiological and perceptual responses of ...
Carlos Segovia‐SanBenito, Alexandre Guimard, Blanca de la Fuente, Pablo González‐Frutos, Santiago Veiga   +4 more
wiley   +1 more source

Reproxalap ‐ A Novel Treatment Option for Allergic Conjunctivitis – A Comprehensive Narrative Review

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Allergic conjunctivitis is a prevalent, immune‐mediated hypersensitivity disorder of the ocular surface affecting 10%–20% of the global population. Current therapeutic options, while effective to some extent, are often limited by side effects and inconsistent efficacy.
Sanila Mughal, Roshanay Ejaz Awan, Hur Abbas, Zahra Sania, Ashna Habib, Syeda Kaneez Sakina, Amina Mahmud, Mohammed Mahmmoud Fadelallah Eljack   +7 more
wiley   +1 more source

Gas Chromatography‐Based Methods for Profiling Volatile Off‐Aroma Compounds in Grain Legumes: A Review

Legume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Instrumental characterisation of the volatile organic compounds (VOCs), responsible for off‐aroma, is mainly centred on gas chromatography‐based techniques. Despite previous reviews that have addressed the chemical compounds and biosynthetic pathways of off‐aroma generation, to date, there is a lack of a comprehensive review that critically ...
Piyumi Chathurangi Wanniarachchi, K. G. Upul Kumarasinghe, Mauro Mocerino, Ranil Coorey   +3 more
wiley   +1 more source