Results 131 to 140 of about 13,296 (264)
The Journal of Physiology, EarlyView.Abstract figure legend High‐altitude acclimatisation increases muscle sympathetic nerve activity (MSNA) via activation of the arterial chemoreflex, pulmonary arterial baroreceptors and resetting of the sympathetic vascular baroreflex. However attempting to silence these mechanisms only partially normalises MSNA, implicating other contributory ...
Liam D. Corr +15 more
wiley +1 more source
Central-peripheral chemoreceptor interaction in awake cerebrospinal fluid-perfused goats
, 1984 We assessed the ventilatory interaction between central [central nervous system (CNS)] and peripheral chemoreceptor stimuli in five awake goats. CNS extracellular fluid (ECF) [H+] was altered with cisterna magna perfusion of mock CSF.
C. A. Smith +4 more
core +1 more source
SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia
The Journal of Physiology, EarlyView.Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu +5 more
wiley +1 more source
Excitatory amino acid receptors within NTS mediate arterial chemoreceptor reflexes in rats
, 1993 The nucleus tractus solitarius (NTS) is the primary site of termination of arterial baroreceptor and chemoreceptor afferent fibers. Excitatory amino acid (EAA) receptors within NTS have been shown to play an important role in the mediation of arterial ...
W. Zhang, S. W. Mifflin
core +1 more source
Mechanisms reducing parasympathetic activity in chronic hypoxia
The Journal of Physiology, EarlyView.Abstract figure legend Parasympathetic activity is reduced in chronic hypoxia, but the underlying mechanism(s) are unclear. Using β‐adrenergic blockade to isolate parasympathetic control of heart rate at sea level and after 9‐12 days at high altitude, we investigated whether (i) chemoreflex activation, (ii) increased pulmonary ventilation and/or (iii ...
Lauren E. Maier +10 more
wiley +1 more source
Maxik potassium channels in the function of chemoreceptor cells of the rat carotid body
, 2013 Hypoxia activates chemoreceptor cells of the carotid body (CB) promoting an increase in their normoxic release of neurotransmitters. Catecholamine (CA) release rate parallels the intensity of hypoxia.
Gómez-Niño, A. +5 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Activation of both the metaboreflex via post‐exercise circulatory occlusion and the chemoreflex via acute and chronic hypoxia increased pulmonary artery systolic pressure. Coactivation of these reflexes further increased pulmonary artery pressure in an additive manner.
Lauren E. Maier +13 more
wiley +1 more source
, 2014 Heart failure (HF) is associated with a large increase in cardiac sympathetic nerve activity (CSNA), which has detrimental effects on the heart and promotes arrhythmias and sudden death. There is increasing evidence that arterial chemoreceptor activation
Ramchandra, Rohit +3 more
core +1 more source
Central and peripheral chemoreceptor inputs to phrenic and hypoglossal motoneurons
, 1982 We tested the hypothesis that phrenic and hypoglossal responses to progressive hypercapnia differ qualitatively because the CO2-related drive inputs to their respective motoneuron pools are different.
N. S. Cherniack, J. Mitra, E. N. Bruce
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Tibetan women livingat high altitude exhibit distinct physiological traits that can enhance oxygen transport in chronic hypoxia. Menopausal status influences cardiopulmonary responses to hypoxia in women living at low altitudes.
E. A. Moya +10 more
wiley +1 more source