Results 151 to 160 of about 14,150 (254)

Exploring neuronal mechanisms of osteosarcopenia in older adults

open access: yesThe Journal of Physiology, Volume 604, Issue 2, Page 672-688, 15 January 2026.
Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley   +1 more source

Acid‐sensing ion channel 1a deficiency drives endocrine hypertension in male mice

open access: yesThe Journal of Physiology, Volume 604, Issue 1, Page 172-192, 1 January 2026.
Abstract figure legend Acid‐sensing ion channel 1a deficiency drives endocrine hypertension in aged male mice. Global deletion of ASIC1a (Asic1a−/−) in adult male mice (6 months old) elevates corticosterone, leading to hypokalaemia, volume expansion, increased pulse pressure and cardiomyocyte hypertrophy.
Selina M. Garcia   +9 more
wiley   +1 more source

Targeting ecto‐5′‐nucleotidase (CD73) and cAMP alleviates carotid body hyperactivity and reduces blood pressure in chronically hypoxic rats

open access: yesThe Journal of Physiology, Volume 604, Issue 1, Page 626-652, 1 January 2026.
Abstract figure legend CD73 promotes carotid body hyperactivity in chronically hypoxic animals. Exposure to chronic hypoxia (CH) (FiO2 of 12% for 10 days) increases the proportion of CD73+TH+ cells in the carotid body and induces basal chemoafferent hyperactivity.
Demitris Nathanael   +4 more
wiley   +1 more source

Physiological responses to short‐term high‐altitude acclimatization: Insights from predictive modeling approaches

open access: yesPhysiological Reports, Volume 14, Issue 1, January 2026.
Abstract High‐altitude (HA) exposure induces cardiovascular, respiratory, and metabolic adjustments that often impair exercise performance. These physiological responses depend on hypoxic severity, exposure duration, and individual susceptibility. Although full acclimatization generally requires about 7 days, early adaptations can emerge within the ...
Valeria Páez   +4 more
wiley   +1 more source

Nitric oxide and carotid body chemoreception

open access: yesBiological Research, 2001
Nitric oxide (NO) has been proposed as an inhibitory modulator of carotid body chemosensory responses to hypoxia. It is believed that NO modulates carotid chemoreception by several mechanisms, which include the control of carotid body vascular tone and ...
RODRIGO ITURRIAGA
doaj  

The Chemoreceptor Sensory Adaptation System Produces Coordinated Reversals of the Flagellar Motors on an Escherichia coli Cell

open access: green, 2022
Yumiko Uchida   +6 more
openalex   +2 more sources

EPAC signalling pathways are involved in low PO2 chemoreception in carotid body chemoreceptor cells

open access: green, 2009
Asunción Rocher   +3 more
openalex   +1 more source

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