Results 131 to 140 of about 11,967,962 (263)

Acid–Base Dysregulation Links Aging Metabolism to Frailty

open access: yesAging Cell, Volume 25, Issue 4, April 2026.
Our Metabolic Buffer Model posits that chronic acid load from aging and accumulated stressors depletes total acid buffer reserve, disrupting intersystem crosstalk. This hidden homeostatic erosion drives clinical frailty and underlies homeostatic failure during stress, unifying Rockwood's deficit accumulation and Fried's phenotype models.
Wan‐Hui Liao   +2 more
wiley   +1 more source

Antagonistic response regulators spatially regulate receptor methylation in the Pseudomonas aeruginosa Pil-Chp surface sensing system

open access: yesCell Reports
Summary: Most bacterial chemosensory systems encode enzymes that are predicted to methylate and demethylate their chemoreceptors to control signaling activity.
Ramiro Patino   +6 more
doaj   +1 more source

Effects of precocene I and II on the sensory system of antennae and mouthparts of Colorado potato beetle larvae, Leptinotarsa decemlineata (Col.: Chrysomelidae) [PDF]

open access: yesنامه انجمن حشره‌شناسی ایران, 2011
The chrysomelid species Leptinotarsa decemlineata (Say), commonly known as Colorado potato beetle (CPB), is an important pest of potato and other solanaceous crops.
S. Yu. Chaika, H. Farazmand
doaj  

Sex Differences in the Effects of Etonogestrel on Respiratory Recovery in an In Vivo Rat Model of Central Chemoreflex Impairment

open access: yesActa Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Rhythmic breathing movements driven by the brainstem rely on chemosensory inputs to homeostatically adjust motor output to the prevailing metabolic demand. The central CO2 chemoreflex is a critical component of this neural circuitry, as defects in these sensors cause hypoventilation syndromes, which are typically difficult to manage ...
Silvia Cardani   +3 more
wiley   +1 more source

Heatwaves and Anthropogenic Light May Disrupt Phototaxis‐Based Behaviours That Regulate Early‐Life Migrations of Fish

open access: yesFreshwater Biology, Volume 71, Issue 4, April 2026.
ABSTRACT Though many fish larvae exhibit phototaxis, its adaptive value is underexplored. Larval fish rely on cues to guide them to suitable nursery habitats and phototaxis enables larvae to react to environmental cues. In the Anthropocene, innate phototactic behaviour might also be disrupted via climate change and habitat alteration.
Barnaby John Roberts   +3 more
wiley   +1 more source

Simultaneous assessment of CO2 sensitivity in the respiratory network and its neurons [PDF]

open access: yes, 2012
This work was funded by the National Science Foundation IOS-1 ...
Reed, Mitchell D.
core  

The genome and stage‐specific transcriptomes of the carrot weevil, Listronotus oregonensis, reveal adaptive mechanisms for host specialisation and symbiotic interactions

open access: yesInsect Molecular Biology, Volume 35, Issue 2, Page 126-138, April 2026.
Comprehensive genome and stage‐specific transcriptomes reveal 14,637 genes in Listronotus oregonensis, advancing genetic insights into a key agricultural pest. Compared with related species, L. oregonensis exhibits reduced chemoreceptor gene families but expanded detoxification gene clusters, reflecting its narrow host range and adaptability.
Dave T. Ste‐Croix   +2 more
wiley   +1 more source

Single-array measurements reveal non-uniform, mosaic-like chemosensory arrays in bacteria

open access: yesNature Communications
Motile bacteria use supramolecular arrays to detect effector gradients in their environment. In Escherichia coli, thousands of chemoreceptor molecules with diverse sensory properties cooperatively modulate the kinase activity of these arrays and, via ...
Vered Frank   +3 more
doaj   +1 more source

The Role of Loss‐of‐Function KCNH2 Variants in Cardiac Arrhythmias, Seizures and the Risk of Sudden Unexpected Death in Epilepsy

open access: yesJournal of Neurochemistry, Volume 170, Issue 4, April 2026.
Seizures can trigger a surge in brain‐driven autonomic signals, causing dangerous changes in heart rhythm and breathing. This ‘storm’ increases stress on the heart, leading to prolonged QT intervals and arrhythmias, while also slowing breathing and causing low oxygen levels. When these effects occur together, they create a vicious cycle that can result
Hian M. Lee   +5 more
wiley   +1 more source

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