Results 121 to 130 of about 7,523 (233)
The Journal of Physiology, EarlyView.Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu +2 more
wiley +1 more source
Cell ReportsSummary: Most bacterial chemosensory systems encode enzymes that are predicted to methylate and demethylate their chemoreceptors to control signaling activity.
Ramiro Patino +6 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins +23 more
wiley +1 more source
Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 7, July 2026.Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen +6 more
wiley +1 more source
Journal of Oral Rehabilitation, Volume 53, Issue 7, Page 1286-1295, July 2026.Oral and functional status differentially modify gustatory assessment in older adults. Salivary and swallowing functions selectively affect strip and solution tests, respectively, highlighting the complementary roles of these methods for comprehensive evaluation and personalised management of taste dysfunction.
Hyo‐Jung Jung +3 more
wiley +1 more source
Single-array measurements reveal non-uniform, mosaic-like chemosensory arrays in bacteria
Nature CommunicationsMotile bacteria use supramolecular arrays to detect effector gradients in their environment. In Escherichia coli, thousands of chemoreceptor molecules with diverse sensory properties cooperatively modulate the kinase activity of these arrays and, via ...
Vered Frank +3 more
doaj +1 more source
Respiratory control at high altitude: The chemoreceptor as a paragon of plasticity
The Journal of Physiology, EarlyView.
Jerome A. Dempsey
wiley +1 more source
Advanced Science, Volume 13, Issue 36, 29 June 2026.This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim +10 more
wiley +1 more source
The formation of polar chemoreceptor clusters is altered in the absence of RecA protein.
, 2014 A) A representative fluorescence microscopy image of the ΔcheR ΔrecA strain harboring plasmid pUA1127, containing the inducible eYFP::cheR fusion. Images of the ΔcheR and ΔcheRΔcheW strains containing the gene fusion were also included as positive and ...
José A. Reyes-Darias (620154) +9 more
core +1 more source
Reproxalap ‐ A Novel Treatment Option for Allergic Conjunctivitis – A Comprehensive Narrative Review
Health Science Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background and Aims Allergic conjunctivitis is a prevalent, immune‐mediated hypersensitivity disorder of the ocular surface affecting 10%–20% of the global population. Current therapeutic options, while effective to some extent, are often limited by side effects and inconsistent efficacy.
Sanila Mughal +7 more
wiley +1 more source