Results 51 to 60 of about 4,582 (179)

Effect of endothelin‐1 on the blood pressure response to acute hypoxia and hyperoxia in healthy young men

Physiological Reports
Endothelin‐1 (ET‐1) and its receptors are linked to increases in sensitivity of the chemoreceptors to hypoxic stress and the development of hypertension in preclinical models. We hypothesized ET receptor antagonism would lower resting blood pressure (BP)
Anna M. Gonsalves, Sarah E. Baker, Dain W. Jacob, Jennifer L. Harper, Camila M. Manrique‐Acevedo, Jacqueline K. Limberg   +5 more
doaj   +1 more source

Feedback from group III/IV afferents in skeletal muscle slows heart rate acceleration when transitioning from rest to low‐intensity exercise in males

Experimental Physiology, EarlyView.
Abstract Group III/IV skeletal muscle afferents respond to intramuscular mechanical and metabolic stimuli and are more active in fatigued muscle. These afferents project onto the brainstem and motor cortex and modulate cardiovascular and motor responses during exercise.
Shane Burgess, Simranjit K Sidhu, Samuel Chalmers, Markus Amann, Jonathan D Buckley   +4 more
wiley   +1 more source

The Nucleus of the Solitary Tract and the coordination of respiratory and sympathetic activities

Frontiers in Physiology, 2014
It is well known that breathing introduces rhythmical oscillations in the heart rate and arterial pressure levels. Sympathetic oscillations coupled to the respiratory activity have been suggested as an important homeostatic mechanism optimizing tissue ...
Daniel B. Zoccal, Werner I. Furuya, Mirian eBassi, Débora S. A. Colombari, Eduardo eColombari   +4 more
doaj   +1 more source

Physiological and autonomic responses to intermittent low‐lung‐volume apnoea and pain sensitivity: A randomized controlled pilot trial

Experimental Physiology, EarlyView.
Abstract Intermittent apnoeas may induce hypoalgesia; however, the effects of low‐lung‐volume static apnoea have not been investigated. Eighty healthy participants were randomized to an apnoea group (AG) or a control group (CG). The AG performed a 6‐min protocol of intermittent static apnoea at low lung volume (passive exhalation), whereas the CG ...
Cristian Mendoza‐Arranz, Francisco De Asís‐Fernández, Guillermo Miravet‐Mingo, José Vicente León‐Hernández, José Fierro‐Marrero, Álvaro Reina‐Varona   +5 more
wiley   +1 more source

Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats

Experimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is a prevalent and complex respiratory disorder associated with recurrent interruptions of air flow during sleep. SA causes sleep fragmentation and intermittent hypoxia which leads to numerous negative health consequences.
Marianne Gagnon, Stéphanie Fournier, François Marcouiller, Natalie J. Michael, Vincent Joseph, Richard Kinkead   +5 more
wiley   +1 more source

Thalia Babbage: Exercise training and chemoreflex sensitivity: endurance trained athletes versus untrained individuals

, 2021
Heightened chemoreflex sensitivity is present in several disease states. At present, therapeutic approaches are limited. Exercise training has many well-known health benefits and may affect chemoreflex sensitivity.
Thalia Babbage (1218054)
core   +1 more source

Ventilatory response to peripheral chemoreflex and muscle metaboreflex during static handgrip in healthy humans: evidence of hyperadditive integration

Experimental Physiology, 2023
Exercise augments the hypoxia‐induced ventilatory response in an exercise intensity‐dependent manner. A mutual influence of hypoxia‐induced peripheral chemoreflex activation and exercise‐induced muscle metaboreflex activation might mediate the ...
Diogo Machado deOliveira, Thiago Ribeiro Lopes, Felipe Silva Gomes, Anas Rashid, Bruno Moreira Silva   +4 more
doaj   +1 more source

Stimulus‐dependent sex differences in dyspnoea: Mechanical loading vs. hypercapnia

Experimental Physiology, EarlyView.
Abstract Dyspnoea is a multidimensional sensation of breathing discomfort that varies in sensory and affective experience. During exercise, healthy adults commonly report dyspnoea sensations of ‘air hunger’ and ‘work/effort’, with females more frequently reporting air hunger at maximal exertion.
Jack R. Dunsford, Olga Radivojevic, Olivia N. Ferguson, Alanna S. Hind, Michele R. Schaeffer, Owen D. Harris, Satvir S. Dhillon, Kathryn M. Milne, Dennis Jensen, Paolo B. Dominelli, Yannick Molgat‐Seon, Jordan A. Guenette   +11 more
wiley   +1 more source

Muscle chemoreflex increases renal sympathetic nerve activity during exercise

, 1997
O’Hagan, Kathleen P., Susan M. Casey, and Philip S. Clifford. Muscle chemoreflex increases renal sympathetic nerve activity during exercise. J. Appl. Physiol.
Susan M. Casey, Philip S. Clifford, Kathleen P. O’Hagan   +2 more
core   +1 more source

Pulmonary arterial mechanoreceptors modulate exercise‐induced sympathetic activation in healthy humans during moderate‐intensity hypoxic exercise

The Journal of Physiology, EarlyView.
Abstract figure legend This randomized cross‐over trial (N = 12) addressed the hypothesis that selective reduction of pulmonary arterial pressure (i.e. manipulation of pulmonary arterial mechanoreceptor activation) during hypoxic exercise would reduce sympathetic outflow (muscle sympathetic nerve activity (MSNA)) in healthy humans.
Michiel T. Ewalts, Thomas D. Griffiths, Andrew J. M. Douglas, Elliott J. Jenkins, Guto Wyn Hughes, Craig D. Steinback, Lydia L. Simpson, Samuel J. Oliver, Mike Stembridge, Jonathan P. Moore   +9 more
wiley   +1 more source